Penicillin Resistance of Nonvaccine Type Pneumococcus before and after PCV13 Introduction, United States

Cheryl P. Andam,C. Worby,R. Gierke,L. McGee,T. Pilishvili,W. Hanage

Published 2017 in Emerging Infectious Diseases

ABSTRACT

Introduction of 13-valent pneumococcal conjugate vaccine in the United States was not associated with a significant change in prevalence of penicillin resistance in nonvaccine type serotypes because of the variable success of highly resistant serotypes. Differences in regional serotype distribution and serotype-specific resistance contributed to geographic heterogeneity of penicillin resistance.

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