Pancreatic and Islet Remodeling in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Knockout Ferrets.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  American Journal of Pathology

• Publication date

  2018-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.ajpath.2017.12.015PMID 29366680PMCID PMC5963477
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regeneration of fat cells from myofibroblasts during wound healing

  2017cited by this paper
• β Cell Aging Markers Have Heterogeneous Distribution and Are Induced by Insulin Resistance.

  2017cited by this paper
• Cystic-fibrosis related-diabetes (CFRD) is preceded by and associated with growth failure and deteriorating lung function

  2017cited by this paper
• Stereological analyses of the whole human pancreas

  2016cited by this paper
• Pancreatic pathophysiology in cystic fibrosis

  2016cited by this paper
• A Transient Metabolic Recovery from Early Life Glucose Intolerance in Cystic Fibrosis Ferrets Occurs During Pancreatic Remodeling.

  2016cited by this paper
• Abnormal Glucose Tolerance in Infants and Young Children with Cystic Fibrosis.

  2016cited by this paper
• Insulin resistance, β-cell dysfunction and differences in curves of plasma glucose and insulin in the intermediate points of the standard glucose tolerance test in adults with cystic fibrosis.

  2015cited by this paper
• Dynamic pathology of islet endocrine cells in type 2 diabetes: β‐Cell growth, death, regeneration and their clinical implications

  2015cited by this paper
• Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass.

  2015cited by this paper
• Lung phenotype of juvenile and adult cystic fibrosis transmembrane conductance regulator-knockout ferrets.

  2014cited by this paper
• Gastrointestinal pathology in juvenile and adult CFTR-knockout ferrets.

  2014cited by this paper
• Increased rate of lung function decline in Australian adolescents with cystic fibrosis

  2014cited by this paper
• Diagnosis and treatment of pancreatic exocrine insufficiency.

  2013cited by this paper
• The cystic fibrosis of exocrine pancreas.

  2013cited by this paper
• Protein Kinase C Iota Regulates Pancreatic Acinar-to-Ductal Metaplasia

  2012cited by this paper
• Abnormal endocrine pancreas function at birth in cystic fibrosis ferrets.

  2012cited by this paper
• Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways.

  2012cited by this paper
• Islet neogenesis: a possible pathway for beta-cell replenishment.

  2012cited by this paper
• New animal models of cystic fibrosis: what are they teaching us?

  2011cited by this paper
• Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition

  2010cited by this paper
• Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats

  2010cited by this paper
• Gene Expression Profiles of Beta-Cell Enriched Tissue Obtained by Laser Capture Microdissection from Subjects with Type 2 Diabetes

  2010cited by this paper
• Identification of Markers for Newly Formed β-Cells in the Perinatal Period: A Time of Recognized β-Cell Immaturity

  2010cited by this paper
• Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis.

  2010cited by this paper
• CFTR Functions as a Bicarbonate Channel in Pancreatic Duct Cells

  2009cited by this paper
• Cystic Fibrosis–Related Diabetes: Current Trends in Prevalence, Incidence, and Mortality

  2009cited by this paper
• Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

  2008cited by this paper
• Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets.

  2008cited by this paper
• Pancreatic stem cells

  2008cited by this paper
• The pancreatic stellate cell: a star on the rise in pancreatic diseases.

  2007cited by this paper
• Matrix metalloproteinase 7 controls pancreatic acinar cell transdifferentiation by activating the Notch signaling pathway

  2007cited by this paper
• Matrix metalloproteinases and the regulation of tissue remodelling

  2007cited by this paper
• Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

  2002cited by this paper
• Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas.

  2002cited by this paper
• Somatostatin Inhibits Insulin and Glucagon Secretion via Two Receptor Subtypes: An in Vitro Study of Pancreatic Islets from Somatostatin Receptor 2 Knockout Mice.

  2000cited by this paper
• Somatostatin inhibits insulin and glucagon secretion via two receptors subtypes: an in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice.

  2000cited by this paper
• Quantitative Immunohistochemical Changes in the Endocrine Pancreas of Nonobese Diabetic (NOD) Mice

  1995cited by this paper
• Relationship of a non-cystic fibrosis transmembrane conductance regulator-mediated chloride conductance to organ-level disease in Cftr(-/-) mice.

  1994cited by this paper
• Insulin Sensitivity in Cystic Fibrosis

  1994cited by this paper

• Unraveling the Connection Between Ion Channels and Pancreatic Stellate Cell Activation.

  2025cites this paper
• Generation of a pseudo-timeline describing progressive human exocrine and endocrine pancreatic pathology in cystic fibrosis through novel semi-quantitative scoring and AI-driven quantitative image analysis

  2025cites this paper
• Stellate cells are in utero markers of pancreatic disease in cystic fibrosis

  2024cites this paper
• Endocrine pathology in young rabbits with cystic fibrosis

  2024cites this paper
• CFTR represses a PDX1 axis to govern pancreatic ductal cell fate

  2024cites this paper
• Changes in immunofluorescence staining during islet regeneration in a cystic fibrosis-related diabetes (CFRD) ferret model

  2024influential citation
• Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes

  2023cites this paper
• Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes

  2023cites this paper
• Animal models of cystic fibrosis in the era of highly effective modulator therapies.

  2022cites this paper
• Screening and Identification of Key Genes for Activation of Islet Stellate Cell

  2021cites this paper
• Cystic Fibrosis

  2021cites this paper
• Animal Models and Their Role in Understanding the Pathophysiology of Cystic Fibrosis-Associated Gastrointestinal Lesions.

  2021cites this paper
• Small extracellular vesicles from human adipose-derived mesenchymal stromal cells: a potential promoter of fat graft survival

  2021cites this paper
• Lack of CFTR alters the ferret pancreatic ductal epithelial secretome and cellular proteome: Implications for exocrine/endocrine signaling.

  2021cites this paper
• The Potential Causes of Cystic Fibrosis-Related Diabetes

  2021cites this paper
• Mechanisms of Post-Pancreatitis Diabetes Mellitus and Cystic Fibrosis-Related Diabetes: A Review of Preclinical Studies

  2021cites this paper
• Understanding the Pancreatic Islet Microenvironment in Cystic Fibrosis and the Extrinsic Pathways Leading to Cystic Fibrosis Related Diabetes

  2021cites this paper
• A peculiar pancreatic lesion: nodular foci of trilineage differentiation and diffuse islet cell hyperplasia

  2021cites this paper
• Small Extracellular Vesicles From Human Adipose-derived Stem Cells: A Potential Promoter of Keeping Fat Graft Survival

  2020cites this paper
• In situ analysis reveals that CFTR is expressed in only a small minority of β-cells in normal adult human pancreas.

  2019cites this paper
• Short-term CFTR inhibition reduces islet area in C57BL/6 mice

  2019cites this paper
• Animal Models: Challenges and Opportunities to Determine Optimal Experimental Models of Pancreatitis and Pancreatic Cancer.

  2019cites this paper
• Cystic Fibrosis–Related Diabetes: Pathophysiology and Therapeutic Challenges

  2019cites this paper
• Incidence and risk factors of paediatric cystic fibrosis-related diabetes.

  2019cites this paper
• Survival in a bad neighborhood: pancreatic islets in cystic fibrosis.

  2019cites this paper
• High glucose alters fetal rat islet transcriptome and induces progeny islet dysfunction.

  2019cites this paper
• Role of the SLC26A9 Chloride Channel as Disease Modifier and Potential Therapeutic Target in Cystic Fibrosis

  2018cites this paper