Nuclear Localization of the Saccharomyces cerevisiae HMG Protein NHP6A Occurs by a Ran‐Independent Nonclassical Pathway

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Traffic : the International Journal of Intracellular Transport

• Publication date

  2001-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1034/j.1600-0854.2001.20703.xPMID 11422939
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mutations in the yeast Nhp6 protein can differentially affect its in vivo functions.

  2001cited by this paper
• Nhp6, an HMG1 protein, functions in SNR6 transcription by RNA polymerase III in S. cerevisiae.

  2001cited by this paper
• Chromatin‐mediated transcriptional regulation by the yeast architectural factors NHP6A and NHP6B

  2000cited by this paper
• Evidence for Separable Functions of Srp1p, the Yeast Homolog of Importin α (Karyopherin α): Role for Srp1p and Sts1p in Protein Degradation

  2000cited by this paper
• Architectural Transcription Factors and the SAGA Complex Function in Parallel Pathways To Activate Transcription

  2000cited by this paper
• Nuclear Export of Map Kinase (ERK) Involves a Map Kinase Kinase (Mek-Dependent) Active Transport Mechanism

  2000cited by this paper
• The Yeast Nuclear Pore Complex: Composition, Architecture, and Transport Mechanism

  2000cited by this paper
• Yeast Nucleoporins Involved in Passive Nuclear Envelope Permeability

  2000cited by this paper
• A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

  2000cited by this paper
• The Yeast Nuclear Pore Complex

  2000cited by this paper
• A new screen for protein interactions reveals that the Saccharomyces cerevisiae high mobility group proteins Nhp6A/B are involved in the regulation of the GAL1 promoter.

  2000cited by this paper
• Solution structure of the HMG protein NHP6A and its interaction with DNA reveals the structural determinants for non‐sequence‐specific binding

  1999cited by this paper
• Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear Targeting

  1999cited by this paper
• The Yck2 yeast casein kinase 1 isoform shows cell cycle-specific localization to sites of polarized growth and is required for proper septin organization.

  1999cited by this paper
• Transport of Proteins and RNAs Review in and out of the Nucleus

  1999cited by this paper
• The MSN1 and NHP6A genes suppress SWI6 defects in Saccharomyces cerevisiae.

  1999cited by this paper
• The Karyopherin Kap122p/Pdr6p Imports Both Subunits of the Transcription Factor Iia into the Nucleus

  1999cited by this paper
• Permeability of single nuclear pores.

  1999cited by this paper
• beta-catenin can be transported into the nucleus in a Ran-unassisted manner.

  1999cited by this paper
• Nucleocytoplasmic transport: the soluble phase.

  1998cited by this paper
• Determinants of DNA binding and bending by the Saccharomyces cerevisiae high mobility group protein NHP6A that are important for its biological activities. Role of the unique N terminus and putative intercalating methionine.

  1998cited by this paper
• In vivo nuclear transport kinetics in Saccharomyces cerevisiae.

  1998cited by this paper
• Karyopherins and kissing cousins.

  1998cited by this paper
• The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus

  1998cited by this paper
• Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of β-catenin

  1998cited by this paper
• Fusion PCR, a one-step variant of the "megaprimer" method of mutagenesis.

  1998cited by this paper
• The green fluorescent protein.

  1998cited by this paper
• Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin.

  1998cited by this paper
• Ran and Nuclear Transport*

  1998influential reference
• Nuclear transport factors: function, behavior and interaction.

  1998cited by this paper
• Nuclear import of protein kinase C occurs by a mechanism distinct from the mechanism used by proteins with a classical nuclear localization signal.

  1998cited by this paper
• Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin β homologs NMD5 and XPO1

  1998cited by this paper
• Nucleocytoplasmic transport: the last 200 nanometers.

  1998cited by this paper
• Nuclear accumulation of HMG2 protein is mediated by basic regions interspaced with a long DNA-binding sequence, and retention within the nucleus requires the acidic carboxyl terminus.

  1997cited by this paper
• Two Independent Nuclear Localization Signals Are Present in the DNA-binding High-mobility Group Domains of SRY and SOX9*

  1997cited by this paper
• Importin/karyopherin protein family members required for mRNA export from the nucleus.

  1997cited by this paper
• Nuclear protein import.

  1997cited by this paper
• The K nuclear shuttling domain: a novel signal for nuclear import and nuclear export in the hnRNP K protein

  1997cited by this paper
• Nuclear accumulation of the U1 snRNP-specific protein C is due to diffusion and retention in the nucleus.

  1997cited by this paper
• A Nuclear Export Signal in Kap95p Is Required for Both Recycling the Import Factor and Interaction with the Nucleoporin GLFG Repeat Regions of Nup116p and Nup100p

  1997cited by this paper
• A Distinct and Parallel Pathway for the Nuclear Import of an mRNA-binding Protein

  1997cited by this paper
• Nucleocytoplasmic transport: signals, mechanisms and regulation

  1997cited by this paper
• Stimulation of V(D)J cleavage by high mobility group proteins

  1997cited by this paper
• Exportin 1 (Crm1p) is an essential nuclear export factor.

  1997cited by this paper
• High-mobility-group chromosomal proteins: architectural components that facilitate chromatin function.

  1996cited by this paper
• Yeast HMG proteins NHP6A/B potentiate promoter-specific transcriptional activation in vivo and assembly of preinitiation complexes in vitro.

  1996cited by this paper
• Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acids.

  1996cited by this paper
• In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation

  1996cited by this paper
• The Nuclear Localization Signal of Lymphoid Enhancer Factor-1 Is Recognized by Two Differentially Expressed Srp1-Nuclear Localization Sequence Receptor Proteins (*)

  1996cited by this paper
• Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins

  1996cited by this paper
• Nucleocytoplasmic Transport

  1996cited by this paper
• Green fluorescent protein as a marker for gene expression and subcellular localization in budding yeast

  1996cited by this paper
• Using CLUSTAL for multiple sequence alignments.

  1996cited by this paper
• Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins.

  1995cited by this paper
• Nuclear localization of the testis determining gene product SRY

  1995cited by this paper
• The yeast nuclear import receptor is required for mitosis.

  1995cited by this paper
• Structural basis for DNA bending by the architectural transcription factor LEF-1

  1995cited by this paper
• Identification of a Yeast Karyopherin Heterodimer That Targets Import Substrate to Mammalian Nuclear Pore Complexes (*)

  1995cited by this paper
• Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins.

  1995cited by this paper
• Structural basis for DNA bending by the architectural transcription factor LEF-1.

  1995cited by this paper
• The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.

  1995influential reference
• Mutants in a yeast Ran binding protein are defective in nuclear transport.

  1995influential reference
• DNA Looping by Saccharomyces cerevisiae High Mobility Group Proteins NHP6A/B

  1995cited by this paper
• GREEN FLUORESCENT PROTEIN

  1995cited by this paper
• A nuclear localization domain in the hnRNP A1 protein

  1995cited by this paper
• NHP6A and NHP6B, which encode HMG1-like proteins, are candidates for downstream components of the yeast SLT2 mitogen-activated protein kinase pathway

  1994cited by this paper
• HMG domain proteins: architectural elements in the assembly of nucleoprotein structures.

  1994cited by this paper
• Architecture of the Xenopus nuclear pore complex revealed by three- dimensional cryo-electron microscopy

  1993cited by this paper
• GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization

  1993cited by this paper
• Isolation of the yeast nuclear pore complex

  1993influential reference
• Movement of the free catalytic subunit of cAMP-dependent protein kinase into and out of the nucleus can be explained by diffusion.

  1993cited by this paper
• CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae

  1993cited by this paper
• Mouse rRNA gene transcription factor mUBF requires both HMG‐box1 and an acidic tail for nucleolar accumulation: molecular analysis of the nucleolar targeting mechanism.

  1992cited by this paper
• Duplicated NHP6 genes of Saccharomyces cerevisiae encode proteins homologous to bovine high mobility group protein 1.

  1990cited by this paper
• EM visualization of nucleocytoplasmic transport processes.

  1990cited by this paper
• The permeability of the nuclear envelope in dividing and nondividing cell cultures

  1990cited by this paper
• Using the polymerase chain reaction

  1990cited by this paper
• Facilitated nuclear transport of histone H1 and other small nucleophilic proteins.

  1990cited by this paper
• A general method for rapid site-directed mutagenesis using the polymerase chain reaction.

  1990cited by this paper
• Yeast proteins that recognize nuclear localization sequences

  1989cited by this paper
• Cloning and characterization of LOS1, a Saccharomyces cerevisiae gene that affects tRNA splicing

  1987cited by this paper
• Amino acid sequences that determine the nuclear localization of yeast histone 2B

  1987cited by this paper
• Methods in Yeast Genetics: A Laboratory Course Manual

  1987cited by this paper
• Nucleocytoplasmic Transport

  1986cited by this paper
• Fluorescence microphotolysis to measure nucleocytoplasmic transport and intracellular mobility.

  1986influential reference
• Sequence requirements for nuclear location of simian virus 40 large-T antigen

  1984cited by this paper
• In vitro mutagenesis of a putative DNA binding domain of SV40 large-T.

  1984cited by this paper
• Nuclear envelope permeability

  1975influential reference
• Copyright © 1997, American Society for Microbiology Nucleocytoplasmic Transport of Macromolecules

  year unknowncited by this paper

• Let go or retain: role of calmodulin in orchestrating nuclear protein transport in eukaryotes

  2026cites this paper
• Arginyltransferase1 drives a mitochondria-dependent program to induce cell death

  2025cites this paper
• Testing mechanisms of DNA sliding by architectural DNA-binding proteins: dynamics of single wild-type and mutant protein molecules in vitro and in vivo

  2021cites this paper
• A synthetic non-histone substrate to study substrate targeting by the Gcn5 HAT and sirtuin HDACs

  2019cites this paper
• High Free-Energy Barrier of 1D Diffusion Along DNA by Architectural DNA-Binding Proteins.

  2018cites this paper
• HMGB Proteins as DNA Chaperones That Modulate Chromatin Activity

  2018cites this paper
• A synthetic non-histone substrate provides insight into substrate targeting by the Gcn5 HAT and sirtuin HDACs

  2018cites this paper
• Facilitated dissociation of transcription factors from single DNA binding sites

  2017cites this paper
• Proteasome-mediated processing of Def1: a critical step in the cellular response to DNA damage

  2013influential citation
• GTP-dependent Binding and Nuclear Transport of RNA Polymerase II by Npa3 Protein*

  2011cites this paper
• Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA

  2010cites this paper
• Nhp6: a small but powerful effector of chromatin structure in Saccharomyces cerevisiae.

  2010cites this paper
• Avian Reovirus SigmaA Localizes to the Nucleolus and Enters the Nucleus by a Nonclassical Energy- and Carrier-Independent Pathway

  2009cites this paper
• Regulation of ribonucleotide reductases in growth and development in the social amoebae Dictyostelium discoideum

  2009cites this paper
• Nucleocytoplasmic transport of proteins

  2007cites this paper
• The High Mobility Group Box Transcription Factor Nhp6Ap Enters the Nucleus by a Calmodulin-dependent, Ran-independent Pathway*

  2007cites this paper
• Determinants of HMGB Proteins Required To Promote RAG1/2-Recombination Signal Sequence Complex Assembly and Catalysis during V(D)J Recombination

  2005cites this paper
• Yeast Nhp6A/B and mammalian Hmgb1 facilitate the maintenance of genome stability.

  2005cites this paper
• The S. cerevisiae architectural HMGB protein NHP6A complexed with DNA: DNA and protein conformational changes upon binding.

  2002cites this paper
• Binding to cisplatin-modified DNA by the Saccharomyces cerevisiae HMGB protein Nhp6A.

  2002cites this paper
• Current awareness on yeast.

  2001cites this paper