Inter-relationship between insulin secretion and plasma free fatty acid and triglyceride transport kinetics in maturity onset diabetes and the effect of phenethylbiguanide (Phenformin)

No abstract is available for this paper.

• Publication year

  1974

• Venue

  Diabetologia

• Publication date

  1974-04-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/BF01219667PMID 4844187
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Serum lipids in men with myocardial infarction.

  2009cited by this paper
• Polymorphism of plasma triglyceride kinetics in normal human adult subjects.

  2009cited by this paper
• Plasma free fatty acid and triglyceride transport kinetics in man.

  1974cited by this paper
• Mechanism of Hypertriglyceridaemia Associated with Contraceptive Steroids

  1973cited by this paper
• Plasma triglyceride transport kinetics in diabetes mellitus.

  1973cited by this paper
• Ischaemic heart-disease in relation to fasting values of plasma triglycerides and cholesterol. Stockholm prospective study.

  1972cited by this paper
• [Blood lipid changes in diabetes mellitus].

  1972cited by this paper
• Tracer Probes in Steady State Systems

  1972cited by this paper
• The In Vitro 14C-Cyclic AMP Production by Normal Human Adipose Tissue in Response to Some Hormones and in Uncontrolled and Controlled Diabetic Adipose Tissue

  1972cited by this paper
• The in vitro 14 C-cyclic AMP production by normal human adipose tissue in response to some hormones and in uncontrolled and controlled diabetic adipose tissue.

  1972cited by this paper
• Lipid disorders in diabetes mellitus.

  1972cited by this paper
• A sensitive, precise radioimmunoassay of serum insulin relying on charcoal separation of bound and free hormone moieties.

  1972cited by this paper
• Alterazioni lipidemiche nel diabete mellito

  1972cited by this paper
• Carbohydrate and lipid oxidation in normal human subjects: its influence on glucose tolerance and insulin response to glucose.

  1972cited by this paper
• The Direct Effect of Oral Hypoglycaemic Agents on Glucose Metabolism by Adipose Tissue

  1972cited by this paper
• Plasma lipoproteins in adult diabetes.

  1972cited by this paper
• Plasma lipids in diabetes mellitus.

  1971cited by this paper
• Plasma lipids in diabetes mellitus.

  1971cited by this paper
• Serum insulin, glucose, and lipid levels among mild diabetics in relation to incidence of vascular complications.

  1971cited by this paper
• [Lipid metabolism disorders and diabetes mellitus].

  1970cited by this paper
• Effect of Experimental Hypertriglyceridaemia on Tissue and Serum Lipoprotein Lipase Activity

  1970cited by this paper
• Hepatic metabolism of free fatty acids in normal and diabetic dogs.

  1970cited by this paper
• Splanchnic metabolism of free fatty acids and production of triglycerides of very low density lipoproteins in normotriglyceridemic and hypertriglyceridemic humans.

  1970cited by this paper
• Fettstoffwechselstörungen und Diabetes mellitus*

  1970cited by this paper
• Application of a new intravenous fat tolerance test in the study of hypertriglyceridaemia in man.

  1969cited by this paper
• Hepatic lipid metabolism in aloxan diabetic rats.

  1969cited by this paper
• Hepatic lipid metabolism in aloxan diabetic rats.

  1969cited by this paper
• Insulin and atheroma.

  1969cited by this paper
• Mechanism of action of antilipolytic agents: comparison of the effects of insulin, tolbutamide, and phenformin on lipolysis induced by dibutyryl cyclic AMP plus theophylline.

  1969cited by this paper
• [Triglyceride level and insulin concentration in plasma following oral glucose administration in patients with primary carbohydrate-induced hypertriglyceridemia].

  1968cited by this paper
• Plasma free fatty acid and triglyceride turnover in obesity.

  1968cited by this paper
• Induction of adipose tissue lipoprotein lipase by nicotinic acid.

  1968cited by this paper
• Clearing-factor lipase in adipose tissue. A possible role of adenosine 3',5'-(cyclic)-monophosphate in the regulation of its activity.

  1968cited by this paper
• Acute Insulin Withdrawal and the Regulation of Plasma Triglyceride Removal in Diabetic Subjects

  1968cited by this paper
• The fluorometric assay of triglyceride by a semiautomated method.

  1968cited by this paper
• Stimulation of insulin secretion by noncarbohydrate metabolites.

  1968cited by this paper
• Interactions of obesity, and glucose and insulin levels in hypertriglyceridemia.

  1968cited by this paper
• Beziehungen zwischen Blutzuckerspiegel, Umsatzrate der freien Fettsäuren und Fettsäureeinbau in Plasmatriglyceride bei Diabetikern

  1967cited by this paper
• Physiologic Effects of Metabolic Fuels on Carbohydrate Metabolism: I. Acute Effect of Elevation of Plasma Free Fatty Acids on Hepatic Glucose Output, Peripheral Glucose Utilization, Serum Insulin, and Plasma Glucagon Levels

  1967cited by this paper
• New automated method for measuring glucose by glucose oxidase

  1967cited by this paper
• Hypoglycaemia and hyperinsulinaemia in response to raised free-fatty-acid levels.

  1967cited by this paper
• [Relations between blood sugar level, free fatty acid turnover rate and fatty acid incorporation into plasma triglycerides in diabetics].

  1967cited by this paper
• Glucose, insulin, and triglyceride responses to high and low carbohydrate diets in man.

  1966influential reference
• Clearing-factor lipase in adipose tissue. A medium in which the enzyme activity of tissue from starved rats increases in vitro.

  1966cited by this paper
• Effects of insulin and diabetes on flux rates of plasma glucose and free fatty acids.

  1966cited by this paper
• Abnormalities in carbohydrate tolerance associated with elevated plasma nonesterified fatty acids.

  1965cited by this paper
• STUDIES IN VITRO ON FATTY ACID METABOLISM OF HUMAN SUBCUTANEOUS ADIPOSE TISSUE IN DIABETES MELLITUS.

  1965cited by this paper
• Kinetics of triglyceride turnover of very low density lipoproteins of human plasma.

  1965cited by this paper
• DETERMINATION OF HEPARIN-INDUCED LIPOPROTEIN LIPASE ACTIVITY IN HUMAN PLASMA.

  1964cited by this paper
• Vascular disease and serum lipids in diabetes mellitus. Observations over thirty years (1931-1961).

  1963cited by this paper
• The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus.

  1963cited by this paper
• Serum lipoproteins, cholesterol and triglycerides in coronary heart disease.

  1962cited by this paper
• Serum lipoproteins, cholesterol and triglycerides in coronary heart disease.

  1962cited by this paper
• The incorporation of plasma free fatty acids into plasma triglycerides in man.

  1961cited by this paper
• A relation between non-esterified fatty acids in plasma and the metabolism of glucose.

  1956cited by this paper

• FoxO1: A Conductor of Insulin Signaling to Glucose and Lipid Metabolism

  2016cites this paper
• HDL levels. A population-based study Hyperinsulinemia is characterized by jointly disturbed plasma VLDL, LDL, and

  2011cites this paper
• FoxO1 integrates insulin signaling to VLDL production

  2008cites this paper
• Central Obesity and the Metabolic Syndrome: Implications for Primary Care Providers

  2004cites this paper
• Association between abdominal wall fat index and carotid atherosclerosis in women.

  2002cites this paper
• High heart rate relates to clustering of cardiovascular risk factors in a screened cohort.

  2001cites this paper
• Treating dyslipidaemia in non-insulin-dependent diabetes mellitus -- a special reference to statins.

  2001cites this paper
• Effects of the FABP2 A54T mutation on triglyceride metabolism of viscerally obese men.

  2001cites this paper
• The effects of gemfibrozil upon the metabolism of chylomicron-like emulsions in patients with endogenous hypertriglyceridemia.

  2001cites this paper
• Insulin resistance, lipid and fatty acid concentrations in 867 healthy Europeans

  2000cites this paper
• Effect of masoprocol on carbohydrate and lipid metabolism in a rat model of Type II diabetes

  1999cites this paper
• The association between dyslipidaemia and obesity in Chinese men after adjustment for insulin resistance.

  1998cites this paper
• Heart rate and the cardiovascular risk

  1997cites this paper
• Are increased plasma non-esterified fatty acid concentrations a risk marker for coronary heart disease and other chronic diseases?

  1996cites this paper
• Adolescent overweight is associated with adult overweight and related multiple cardiovascular risk factors: the Bogalusa Heart Study.

  1996cites this paper
• The ApoB-100 Gene EcoRI Polymorphism Influences the Relationship Between Features of the Insulin Resistance Syndrome and the Hyper-ApoB and Dense LDL Phenotype in Men

  1996cites this paper
• The associations of high-density lipoprotein subclasses with insulin and glucose levels, physical activity, resting heart rate, and regional adiposity in men with coronary artery disease: the Stanford Coronary Risk Intervention Project baseline survey.

  1995cites this paper
• Fetal Growth and Insulin Resistance in Adult Life: Role of Plasma Triglyceride and Non‐esterified Fatty Acids

  1995cites this paper
• Relationship between insulin resistance and abnormal lipid profile in obese adolescents.

  1995cites this paper
• Dexfenfluramine inhibits catecholamine stimulated in vitro lipolysis in human fat cells.

  1995cites this paper
• Dyslipidaemia and obesity.

  1994cites this paper
• In vivo regulation of lipolysis in humans.

  1994cites this paper
• The effect of an antilipolytic agent (acipimox) on the insulin resistance of lipid and glucose metabolism in hypertriglyceridaemic patients

  1994cites this paper
• The relationships of abdominal obesity, hyperinsulinemia and saturated fat intake to serum lipid levels: the Normative Aging Study.

  1994cites this paper
• Hypertriglyceridaemia in subjects with normal and abnormal glucose tolerance: relative contributions of insulin secretion, insulin resistance and suppression of plasma non-esterified fatty acids

  1994cites this paper
• Glycometabolic control, lipids, and coagulation parameters in patients with non-insulin-dependent diabetes mellitus

  1993cites this paper
• Coexistence of increased levels of adiposity, insulin, and blood pressure in a young adult cohort with elevated very-low-density lipoprotein cholesterol: the Bogalusa Heart Study.

  1993cites this paper
• Insulin resistance, adipose tissue and coronary heart disease.

  1992cites this paper
• Adipose tissue metabolism in obesity: lipase action in vivo before and after a mixed meal.

  1992cites this paper
• The good, the bad, and the ugly in diabetic diets.

  1992cites this paper
• Lipogenic potential of liver from morbidly obese patients with and without non-insulin-dependent diabetes.

  1991cites this paper
• Effects of Dietary Carbohydrate and Fat Intake on Glucose and Lipoprotein Metabolism in Individuals With Diabetes Mellitus

  1991cites this paper
• Lipogenesis in diabetes and obesity.

  1991cites this paper
• Hyperinsulinemia or Increased Sympathetic Drive as Links for Obesity and Hypertension

  1991cites this paper
• Insulin, Indian origin and ischaemic heart disease.

  1990cites this paper
• Persistence of Hypertriglyceridemic Effect of Low-Fat High-Carbohydrate Diets in NIDDM Patients

  1989cites this paper
• Biology of regional body fat distribution: relationship to non-insulin-dependent diabetes mellitus.

  1989cites this paper
• Apolipoprotein, Low Density Lipoprotein Subtraction, and Insulin Associations with Familial Combined Hyperlipidemia: Study of Utah Patients with Familial Dyslipidemic Hypertension

  1989cites this paper
• Human genetics and coronary heart disease: a public health perspective.

  1989cites this paper
• Role of insulin in regulation of lipoprotein metabolism in diabetes.

  1988cites this paper
• Polyunsaturated and Saturated Fat, Cholesterol, and Fatty Add Supplementation

  1988cites this paper
• Hyperinsulinemia, upper body adiposity, and cardiovascular risk factors in non-diabetics.

  1988cites this paper
• Hyperinsulinemia Is Characterized by Jointly Disturbed Plasma VLDL, LDL, and HDL Levels: A Population‐Based Study

  1988cites this paper
• Effect of insulin treatment on fatty acids of plasma and erythrocyte membrane lipids in type 2 diabetes.

  1988cites this paper
• Very low density lipoprotein metabolism in diabetes mellitus.

  1987cites this paper
• HDL metabolism in diabetes.

  1987cites this paper
• Hormones and lipoprotein metabolism.

  1987cites this paper
• Effect of variation in diet on lipoprotein metabolism in patients with diabetes mellitus.

  1987cites this paper
• Lipoprotein metabolism in diabetes mellitus.

  1987cites this paper
• Low density lipoprotein metabolism in non-insulin-dependent diabetes mellitus.

  1987cites this paper
• A longitudinal study of adipose tissue glucose utilization during pregnancy and the puerperium in normal subjects.

  1986cites this paper
• Abnormal composition of apoproteins C-I, C-II, and C-III in plasma and very-low-density lipoproteins of non-insulin-dependent diabetic Chinese.

  1986cites this paper
• Effects of NIDDM on Very-Low-Density Lipoprotein Triglyceride and Apolipoprotein B Metabolism: Studies Before and After Sulfonylurea Therapy

  1986cites this paper
• Influence of metformin on metabolic effect of insulin in human adipose tissue in vitro.

  1984cites this paper
• The relationship between the level of lipidemia and the macrovascular complications of diabetes.

  1984cites this paper
• Plasma low density lipoprotein transport kinetics in noninsulin-dependent diabetes mellitus.

  1983cites this paper
• Very low density lipoprotein metabolism in non-ketotic diabetes mellitus: Effect of dietary restriction

  1982cites this paper
• Effect of in vivo increase of free fatty acids on human plasma protein binding of furosemide.

  1982cites this paper
• Metabolism of Cholesterol and Plasma Triglycerides in Nonketotic Diabetes Mellitus

  1982cites this paper
• Integrated Regulation of Very Low Density Lipoprotein Triglyceride and Apolipoprotein-B Kinetics in Non-insulin-dependent Diabetes Mellitus

  1982cites this paper
• A simplified approach to lipoprotein kinetics and factors affecting serum cholesterol and triglyceride concentrations.

  1981cites this paper
• Diabetic Hypertriglyceridemia: Evidence for Three Clinical Syndromes

  1981cites this paper
• Hyperinsulinemia in patients with low fractional catabolic rate of triglycerides

  1981cites this paper
• Mechanism of hypertriglyceridaemia in diabetic patients with fasting hyperglycaemia

  1980cites this paper
• Fatty acids, fibrinogen and blood flow: a general mechanism for hyperfibrinogenemia and its pathologic consequences.

  1980cites this paper
• Evidence for multiple causality in the development of diabetic hypertriglyceridaemia

  1980cites this paper
• Hyperlipidaemia and treatment of diabetes.

  1979cites this paper
• Is the Hypertriglyceridemia Associated with Insulin Deficiency Caused by Decreased Lipoprotein Lipase Activity?

  1979cites this paper
• Nutritional management of diabetes.

  1979cites this paper
• Suppression of tumor-associated hyperfibrinogenemia and free fatty acidemia with p-phenoxybenzalbutyrate (clofibrate).

  1979cites this paper
• Increased concentrations of free fatty acids and glycerol and altered creatine kinase MM isoenzyme patterns in certain diabetic patients.

  1979cites this paper
• Effects of metformin on plasma glucose, insulin, FFA, glucagon, growth hormone and cortisol responses to oral glucose in subjects with chemical diabetes.

  1979cites this paper
• The effects of phenformin and metformin on fat and carbohydrate metabolism

  1977cites this paper
• [Treatment of primary hyperlipoproteinemia type IIb and IV. Comparison of the lipid lowering effect of phenformin, clofibrate, and a combination of both (author's transl)].

  1977cites this paper
• Postheparin Plasma Lipoprotein Lipase and Hepatic Lipase in Diabetes Mellitus: Relationship to Plasma Triglyceride Metabolism

  1977cites this paper
• Metabolic effects of buformin on the isolated perfused rat hindlimb during electrical stimulation.

  1977cites this paper
• Hypolipidemic effects of metformin in hyperprebetalipoproteinemia.

  1976cites this paper
• Transport kinetics of plasma free fatty acid, very low density lipoprotein triglycerides and apoprotein in patients with endogenous hypertriglyceridaemia: effects of 2,2-dimethyl, 5(2, 5-xylyoxy) valeric acid therapy.

  1976cites this paper
• [Investigations of the mode action of buformin using a 3H-labelled glucose in people with a healthy metabolism (author's transl)].

  1976cites this paper
• Effects of Insulin and Procaine Hydrochloride on Glycogen Synthetase Activation and Adipocyte Calcium Flux: Evidence for a Role of Calcium in Insulin Activation of Glycogen Synthetase

  1976cites this paper
• Editorial: Phenformin and hypertension.

  1975cites this paper
• Plasma-lipids and glucose/insulin relationship in non-insulin-requiring diabetics with and without retinopathy.

  1975cites this paper
• Determinants of human adipose tissue lipoprotein lipase. Effect of diabetes and obesity on basal- and diet-induced activity.

  1975cites this paper
• The effect of phenformin-HCl on patients with diabetes mellitus, studied under strict balance conditions

  1975cites this paper
• Effect of glucose infusion on venous blood levels of immunoreactive proinsulin activity, insulin activity and fat parameters in healthy and protodiabetic subjects.

  1975cites this paper
• Plasma free fatty acid and triglyceride transport kinetics in man.

  1974cites this paper
• The Kinetics of Plasma Free Fatty Acid and Triglyceride Transport in Patients with Idiopathic Hypertriglyceridaemia and Their Relation to Carbohydrate Metabolism

  1974cites this paper
• The Mechanism of Action of Clofibrate and Tetranicotinoylfructose (Bradilan) on the Kinetics of Plasma Free Fatty Acid and Triglyceride Transport in Type IV und Type V Hypertriglyceridaemia

  1974cites this paper