The Triplet Genetic Code had a Doublet Predecessor

Apoorva D. Patel

Published 2004 in Journal of Theoretical Biology

ABSTRACT

Information theoretic analysis of genetic languages indicates that the naturally occurring 20 amino acids and the triplet genetic code arose by duplication of 10 amino acids of class-II and a doublet genetic code having codons NNY and anticodons GNN. Evidence for this scenario is presented based on the properties of aminoacyl-tRNA synthetases, amino acids and nucleotide bases.

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