Estimation of Multilocus Haplotype Effects Using Weighted Penalised Log‐Likelihood: Analysis of Five Sequence Variations at the Cholesteryl Ester Transfer Protein Gene Locus

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Annals of Human Genetics

• Publication date

  2003-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1469-1809.2003.00021.xPMID 12675692
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Haplotype analysis of the CETP gene: not TaqIB, but the closely linked -629C-->A polymorphism and a novel promoter variant are independently associated with CETP concentration.

  2003cited by this paper
• Specific haplotypes of the P-selectin gene are associated with myocardial infarction.

  2002cited by this paper
• Haplotype frequency estimation in patient populations: The effect of departures from Hardy‐Weinberg proportions and collapsing over a locus in the HLA region

  2002cited by this paper
• Effectiveness of computational methods in haplotype prediction

  2002cited by this paper
• Effect of intensive lipid-lowering strategy on low-density lipoprotein particle size in patients with type 2 diabetes mellitus.

  2001cited by this paper
• A new statistical method for haplotype reconstruction from population data.

  2001influential reference
• Bayes Estimates of Haplotype Effects

  2001cited by this paper
• Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene‐environment interaction

  2000cited by this paper
• Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data.

  2000cited by this paper
• New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: role of Sp1/Sp3 in transcriptional regulation.

  2000cited by this paper
• Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci.

  1999cited by this paper
• Analysis of lipoprotein lipase haplotypes reveals associations not apparent from analysis of the constituent loci

  1999cited by this paper
• Cholesteryl ester transfer protein gene effect on CETP activity and plasma high‐density lipoprotein in European populations

  1999cited by this paper
• Association between plasma HDL-cholesterol concentration and Taq1B CETP gene polymorphism in non-insulin-dependent diabetes mellitus.

  1998cited by this paper
• Validation of haplotype frequency estimation methods.

  1998cited by this paper
• Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol levels.

  1997cited by this paper
• Testing for linkage disequilibrium in genotypic data using the Expectation-Maximization algorithm

  1996cited by this paper
• Flexible smoothing with B-splines and penalties

  1996cited by this paper
• Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

  1995cited by this paper
• Relationship of high-density lipoprotein subfractions and cholesteryl ester transfer protein in plasma to carotid artery wall thickness

  1995cited by this paper
• An E-M algorithm and testing strategy for multiple-locus haplotypes.

  1995cited by this paper
• Effects of lipid lowering by pravastatin on progression and regression of coronary artery disease in symptomatic men with normal to moderately elevated serum cholesterol levels. The Regression Growth Evaluation Statin Study (REGRESS).

  1995cited by this paper
• The effect of variation in the apolipoprotein B gene on plasma lipid and apolipoprotein B levels I. A likelihood‐based approach to cladistic analysis

  1994cited by this paper
• A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. IV. Nested analyses with cladogram uncertainty and recombination.

  1993cited by this paper
• Performing the exact test of Hardy-Weinberg proportion for multiple alleles.

  1992cited by this paper
• Inference of haplotypes from PCR-amplified samples of diploid populations.

  1990cited by this paper
• Polymorphisms in the gene coding for cholesteryl ester transfer protein are related to plasma high-density lipoprotein cholesterol and transfer protein activity.

  1990cited by this paper
• High-density lipoprotein--the clinical implications of recent studies.

  1989cited by this paper
• A cladistic analysis of phenotype associations with haplotypes inferred from restriction endonuclease mapping. II. The analysis of natural populations.

  1988cited by this paper
• A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila.

  1987cited by this paper
• Multiple RFLPs at the human cholesteryl ester transfer protein (CETP) locus.

  1987cited by this paper
• The general relationship between average effect and average excess.

  1987cited by this paper
• Model robust confidence intervals using maximum likelihood estimators

  1986cited by this paper
• Comparison of improved precipitation methods for quantification of high-density lipoprotein cholesterol.

  1985cited by this paper
• Finding the Observed Information Matrix When Using the EM Algorithm

  1982cited by this paper

• Penalized-regression-based multimarker genotype analysis of Genetic Analysis Workshop

  2011cites this paper
• Penalized-regression-based multimarker genotype analysis of Genetic Analysis Workshop 17 data

  2011cites this paper
• Evaluating haplotype effects in case‐control studies via penalized‐likelihood approaches: prospective or retrospective analysis?

  2010cites this paper
• Clinical and Population Studies Chemokine Ligand 2 Genetic Variants , Serum Monocyte Chemoattractant Protein-1 Levels , and the Risk of Coronary Artery Disease

  2010cites this paper
• Haplotype association analyses in resources of mixed structure using Monte Carlo testing

  2010cites this paper
• A comprehensive approach to haplotype-specific analysis by penalized likelihood

  2010cites this paper
• Chemokine Ligand 2 Genetic Variants, Serum Monocyte Chemoattractant Protein-1 Levels, and the Risk of Coronary Artery Disease

  2010cites this paper
• Inflammation and its echo in atherosclerosis

  2009cites this paper
• Study on Effects of Population Stratification on Haplotype Trend Test in Case-Control Studies

  2009cites this paper
• Association mapping by generalized linear regression with density‐based haplotype clustering

  2009cites this paper
• Analysis of Population-Based Genetic Association Studies Applied to Cancer Susceptibility and Prognosis

  2009cites this paper
• Improving Genetic Analysis of Case-Control Studies

  2008influential citation
• The power of independent types of genetic information to detect association in a case‐control study design

  2008cites this paper
• Estimating effects of rare haplotypes on failure time using a penalized Cox proportional hazards regression model

  2008cites this paper
• Striatal Dopamine Transporter Availability Associated with Polymorphisms in the Dopamine Transporter Gene SLC6A3

  2008cites this paper
• Haplotype-association analysis.

  2008cites this paper
• VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.

  2008cites this paper
• Platelet receptor P2RY12 haplotypes predict restenosis after percutaneous coronary interventions

  2008cites this paper
• TUMOR NECROSIS FACTOR-α PLAYS AN IMPORTANT ROLE IN RESTENOSIS DEVELOPMENT

  2007cites this paper
• Association mapping via regularized regression analysis of single-nucleotide-polymorphism haplotypes in variable-sized sliding windows.

  2007cites this paper
• Methods for analysing genetic association studies : application to cardiovascular disease

  2007influential citation
• Interleukin 10: a new risk marker for the development of restenosis after percutaneous coronary intervention

  2007cites this paper
• Genetic variation in estrogen receptor, C-reactive protein and fibrinogen does not predict the plasma levels of inflammation markers after longterm hormone replacement therapy

  2007cites this paper
• UvA-DARE ( Digital Academic Repository ) Spermatogenic failure . A genetic

  2007cites this paper
• Impact of complex genetic variation in COMT on human brain function

  2006cites this paper
• 7 lipoprotein lipase Gene polymorphisms and the risk of tarGet vessel revascularization after percutaneous coronary intervention

  2006cites this paper
• 10 interleukin 10 : a new risk marker for the development of restenosis after percutaneous coronary intervention

  2006cites this paper
• Estimating Haplotype Effects on Dichotomous Outcome for Unphased Genotype Data Using a Weighted Penalized Log-Likelihood Approach

  2006cites this paper
• Longitudinal analysis of haplotypes and polymorphisms of the APOA5 and APOC3 genes associated with variation in serum triglyceride levels: the Bogalusa Heart Study.

  2006cites this paper
• The effect of genetic variants in the thrombin activatable fibrinolysis inhibitor (TAFI) gene on TAFI‐antigen levels, clot lysis time and the risk of venous thrombosis

  2006cites this paper
• Estimation and testing of genotype and haplotype effects in case‐control studies: comparison of weighted regression and multiple imputation procedures

  2006cites this paper
• Lipoprotein lipase S447X : from benefical gene variant to gene therapy

  2006cites this paper
• Tumor necrosis factor-alpha plays an important role in restenosis development.

  2005cites this paper
• High functional levels of thrombin‐activatable fibrinolysis inhibitor are associated with an increased risk of first ischemic stroke

  2005cites this paper
• Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study.

  2005cites this paper
• Lipoprotein lipase gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention.

  2005cites this paper
• Genetic Inflammatory Factors Predict Restenosis After Percutaneous Coronary Interventions

  2005cites this paper
• Study of a new PPARgamma2 promoter polymorphism and haplotype analysis in a French population.

  2005cites this paper
• The cardiovascular metabolic syndrome

  2005cites this paper
• Tumor necrosis factor- (cid:1) plays an important role in restenosis development

  2005cites this paper
• Estimating Haplotype Relative Risks on Human Survival in Population-Based Association Studies

  2005cites this paper
• A Note on Inference of Trait Associations with SNP Haplotypes and Other Attributes in Generalized Linear Models

  2004cites this paper
• Genetics of familial combined hyperlipidemia and risk of coronary heart disease.

  2004cites this paper
• Assessment of Genetic Association using Haplotypes Inferred with Uncertainty

  2004cites this paper
• Haplotype Association Analysis of Discrete and Continuous Traits Using Mixture of Regression Models

  2004cites this paper
• Simultaneous Estimation of Haplotype Frequencies and Quantitative Trait Parameters

  2004cites this paper
• COX PROPORTIONNAL HAZARDS ANALYSIS FOR HAPLOTYPE- BASED ASSOCIATION ANALYSIS: THE STOCHASTIC-EM ALGORITHM

  2004cites this paper
• Role of P2RY12 Gene Variants and Biological Variation in Arterial Thrombosis

  2004cites this paper
• Cox proportional hazards survival regression in haplotype-based association analysis using the Stochastic-EM algorithm

  2004cites this paper
• The future of association studies: gene-based analysis and replication.

  2004cites this paper
• Evaluating associations of haplotypes with traits

  2004influential citation
• Common Variation in Genes Involved in HDL Metabolism Influences Coronary Heart Disease Risk at the Population Level

  2004cites this paper
• Thrombin Avtivable Fibrinolysis Inhibitor in Venous and Arterial Thrombosis

  2003cites this paper
• Modeling and E-M Estimation of Haplotype-Specific Relative Risks from Genotype Data for a Case-Control Study of Unrelated Individuals

  2003cites this paper
• Chromosomal region 11p15 is associated with male factor subfertility.

  2003cites this paper
• Association Mapping by Generalized Linear Regression with Density-based Haplotype Clustering

  year unknowncites this paper