Physical and functional crosstalk between Fanconi anemia core components and the GINS replication complex.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  DNA Repair

• Publication date

  2011-02-07

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.dnarep.2010.10.006PMID 21109493
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability.

  2010cited by this paper
• ATR activation and replication fork restart are defective in FANCM‐deficient cells

  2010cited by this paper
• A novel role for fanconi anemia (FA) pathway effector protein FANCD2 in cell cycle progression of untransformed primary human cells

  2010cited by this paper
• Expanded roles of the Fanconi anemia pathway in preserving genomic stability.

  2010cited by this paper
• MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM.

  2010cited by this paper
• FANCM regulates DNA chain elongation and is stabilized by S‐phase checkpoint signalling

  2010cited by this paper
• The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

  2009cited by this paper
• FANCM connects the genome instability disorders Bloom's Syndrome and Fanconi Anemia.

  2009cited by this paper
• Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication.

  2009cited by this paper
• The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

  2009cited by this paper
• The genetic and molecular basis of Fanconi anemia.

  2009cited by this paper
• The Fanconi anemia protein interaction network: casting a wide net.

  2009cited by this paper
• Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

  2009cited by this paper
• Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.

  2009cited by this paper
• FANCM-FAAP24 and FANCJ: FA proteins that metabolize DNA.

  2009cited by this paper
• Regulated degradation of FANCM in the Fanconi anemia pathway during mitosis.

  2009cited by this paper
• Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy

  2008cited by this paper
• FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair.

  2008cited by this paper
• Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

  2008cited by this paper
• Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24.

  2008cited by this paper
• FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.

  2008cited by this paper
• The Fanconi anemia protein FANCM can promote branch migration of Holliday junctions and replication forks.

  2008cited by this paper
• Remodeling of DNA replication structures by the branch point translocase FANCM

  2008cited by this paper
• Fanconi anemia proteins stabilize replication forks.

  2008cited by this paper
• Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.

  2007cited by this paper
• Cell cycle regulation of DNA replication.

  2007cited by this paper
• UBE2T, the Fanconi Anemia Core Complex, and FANCD2 Are Recruited Independently to Chromatin: a Basis for the Regulation of FANCD2 Monoubiquitination

  2007cited by this paper
• Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.

  2007cited by this paper
• Structural Determinants of Human FANCF Protein That Function in the Assembly of a DNA Damage Signaling Complex*

  2007cited by this paper
• A key role for the GINS complex at DNA replication forks.

  2007cited by this paper
• Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

  2007cited by this paper
• ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage

  2007cited by this paper
• Differential Requirements for MCM Proteins in DNA Replication in Drosophila S2 Cells

  2007cited by this paper
• Fanconi Anemia Proteins Are Required To Prevent Accumulation of Replication-Associated DNA Double-Strand Breaks

  2006cited by this paper
• ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks

  2006cited by this paper
• One-step high-throughput assay for quantitative detection of beta-galactosidase activity in intact gram-negative bacteria, yeast, and mammalian cells.

  2006cited by this paper
• Fanconi anemia (cross)linked to DNA repair.

  2005cited by this paper
• The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability.

  2005cited by this paper
• A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair.

  2005cited by this paper
• The Fanconi anemia core complex associates with chromatin during S phase.

  2005cited by this paper
• The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway

  2005cited by this paper
• The Fanconi Anemia Gene Product FANCF Is a Flexible Adaptor Protein*

  2004cited by this paper
• DNA polymerase α inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

  2004cited by this paper
• A novel ubiquitin ligase is deficient in Fanconi anemia

  2003cited by this paper
• A novel ring-like complex of Xenopus proteins essential for the initiation of DNA replication.

  2003cited by this paper
• GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

  2003cited by this paper
• Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.

  2003cited by this paper
• C dil, a Human Gl and S Phase Protein Phosphatase That Associates with Cdk2

  2003cited by this paper
• Functional proteomic identification of DNA replication proteins by induced proteolysis in vivo

  2003cited by this paper
• The 4N cell cycle delay in Fanconi anemia reflects growth arrest in late S phase.

  2001cited by this paper
• Fanconi Anemia Proteins Localize to Chromatin and the Nuclear Matrix in a DNA Damage- and Cell Cycle-regulated Manner*

  2001cited by this paper
• The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG.

  2000cited by this paper
• Cumulative Effect of Phosphorylation of pRB on Regulation of E2F Activity

  1999cited by this paper
• p16 proteins from melanoma-prone families are deficient in binding to Cdk4.

  1995cited by this paper

• Repair of DNA double-strand breaks in plant meiosis: role of eukaryotic RecA recombinases and their modulators

  2022cites this paper
• GINS2 facilitates epithelial‐to‐mesenchymal transition in non‐small‐cell lung cancer through modulating PI3K/Akt and MEK/ERK signaling

  2020cites this paper
• Zelluläre Untersuchungen zur Funktion des hSNM1B/Apollo-Proteins unter Berücksichtigung von DNA-Schadensantwort und Telomerlänge

  2019influential citation
• GINS 2 regulates cell proliferation and apoptosis in human epithelial ovarian cancer

  2018cites this paper
• GINS2 regulates cell proliferation and apoptosis in human epithelial ovarian cancer.

  2018cites this paper
• SNM1B/Apollo in the DNA damage response and telomere maintenance

  2017cites this paper
• – (-) Menthol Induces Reversal of Promoter Hypermethylation and Associated Up-Regulation of the FANCF Gene in the SiHa Cell Line

  2017cites this paper
• ATR-mediated phosphorylation of FANCI regulates dormant origin firing in response to replication stress.

  2015cites this paper
• High GINS2 transcript level predicts poor prognosis and correlates with high histological grade and endocrine therapy resistance through mammary cancer stem cells in breast cancer patients

  2014cites this paper
• Fanconi anemia pathway--the way of DNA interstrand cross-link repair.

  2013cites this paper
• Non-Canonical CRL4A/4BCDT2 Interacts with RAD18 to Modulate Post Replication Repair and Cell Survival

  2013cites this paper
• RNAi-mediated knockdown of FANCF suppresses cell proliferation, migration, invasion, and drug resistance potential of breast cancer cells

  2013cites this paper
• Demethylation of FANCF gene may be a potential treatment through inhibiting the proliferation of cervical cancer

  2013cites this paper
• The GINS complex: structure and function.

  2012cites this paper
• Gene Silencing of FANCF Potentiates the Sensitivity to Mitoxantrone through Activation of JNK and p38 Signal Pathways in Breast Cancer Cells

  2012cites this paper
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• Elucidation of Snm1B Function

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• Snm1B Interacts with PSF2

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• The Eukaryotic Replisome: a Guide to Protein Structure and Function

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