Effect on Polyomavirus T-Antigen Function of Mutations in a Conserved Leucine-Rich Segment of the DnaJ Domain

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Virology

• Publication date

  2001-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/JVI.75.5.2253-2261.2001PMID 11160729PMCID PMC114809
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Tiny T antigen: an autonomous polyomavirus T antigen amino-terminal domain

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  1990cited by this paper
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• Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

  1990cited by this paper
• Mechanisms of transformation by polyoma virus middle T antigen.

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