Synthesis of sulfonamides with effective inhibitory action against Porphyromonas gingivalis γ-carbonic anhydrase.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Bioorganic & Medicinal Chemistry Letters

• Publication date

  2014-08-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bmcl.2014.06.024PMID 25011913
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?

  2015cited by this paper
• Sulfonamide inhibition studies of the δ-carbonic anhydrase from the diatom Thalassiosira weissflogii.

  2014cited by this paper
• Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.

  2014cited by this paper
• The structural comparison between membrane‐associated human carbonic anhydrases provides insights into drug design of selective inhibitors

  2014cited by this paper
• A small-molecule drug conjugate for the treatment of carbonic anhydrase IX expressing tumors.

  2014cited by this paper
• Sulfonamide inhibition studies of two β-carbonic anhydrases from the bacterial pathogen Legionella pneumophila.

  2014cited by this paper
• Sulfonamide inhibition studies of the γ-carbonic anhydrase from the oral pathogen Porphyromonas gingivalis.

  2014cited by this paper
• Cloning, characterization and anion inhibition study of the δ-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii.

  2014cited by this paper
• Biochemical properties of a new α-carbonic anhydrase from the human pathogenic bacterium, Vibrio cholerae

  2014cited by this paper
• Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases.

  2013cited by this paper
• Cleavage of extracellular matrix in periodontitis: gingipains differentially affect cell adhesion activities of fibronectin and tenascin-C.

  2013cited by this paper
• Cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Leishmania donovani chagasi, the protozoan parasite responsible for leishmaniasis.

  2013cited by this paper
• Porphyromonas gingivalis Virulence Factor Gingipain RgpB Shows a Unique Zymogenic Mechanism for Cysteine Peptidases*

  2013cited by this paper
• Carbonic anhydrases of anaerobic microbes.

  2013cited by this paper
• Dihalogenated sulfanilamides and benzolamides are effective inhibitors of the three β-class carbonic anhydrases from Mycobacterium tuberculosis

  2013cited by this paper
• Anti-infective carbonic anhydrase inhibitors: a patent and literature review

  2013cited by this paper
• Carbonic anhydrase inhibitors: an editorial

  2013cited by this paper
• Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens.

  2013cited by this paper
• Carbonic anhydrases.

  2013cited by this paper
• Structural annotation of human carbonic anhydrases

  2013cited by this paper
• Anion inhibition studies of the α-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease.

  2013cited by this paper
• Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors.

  2013cited by this paper
• Inhibition of the β-carbonic anhydrases from Mycobacterium tuberculosis with C-cinnamoyl glycosides: identification of the first inhibitor with anti-mycobacterial activity.

  2013cited by this paper
• A highly catalytically active γ-carbonic anhydrase from the pathogenic anaerobe Porphyromonas gingivalis and its inhibition profile with anions and small molecules.

  2013cited by this paper
• Inhibition of the β-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids

  2013cited by this paper
• Sulfonamides: a patent review (2008 – 2012)

  2012cited by this paper
• Structure-based drug discovery of carbonic anhydrase inhibitors

  2012cited by this paper
• Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?

  2012cited by this paper
• Bacterial Carbonic Anhydrases as Drug Targets: Toward Novel Antibiotics?

  2011cited by this paper
• Interfering with pH regulation in tumours as a therapeutic strategy

  2011cited by this paper
• Carbonic anhydrase inhibitors and activators for novel therapeutic applications.

  2011cited by this paper
• Inhibition of the β-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?

  2011cited by this paper
• Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.

  2010cited by this paper
• Dichotomy of gingipains action as virulence factors: from cleaving substrates with the precision of a surgeon's knife to a meat chopper-like brutal degradation of proteins.

  2010cited by this paper
• Verification of a topology model of PorT as an integral outer-membrane protein in Porphyromonas gingivalis.

  2009cited by this paper
• Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.

  2009cited by this paper
• The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths*

  2009cited by this paper
• The alpha and beta classes carbonic anhydrases from Helicobacter pylori as novel drug targets.

  2008cited by this paper
• The α and β Classes Carbonic Anhydrases from Helicobacter pylori as Novel Drug Targets

  2008cited by this paper
• Carbonic anhydrases: novel therapeutic applications for inhibitors and activators

  2008cited by this paper
• Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.

  2007cited by this paper
• Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.

  2006cited by this paper
• A Role for Iron in an Ancient Carbonic Anhydrase*

  2004cited by this paper
• Designing of Novel Carbonic Anhydrase Inhibitors and Activators.

  2004cited by this paper
• Designing of novel carbonic anhydrase inhibitors and activators.

  2004cited by this paper
• Carbonic anhydrase inhibitors.

  2003cited by this paper
• Bacterial proteases: current therapeutic use and future prospects for the development of new antibiotics

  2001cited by this paper
• Prokaryotic carbonic anhydrases.

  2000cited by this paper
• Carbonic anhydrase inhibitors: synthesis of water-soluble, aminoacyl/dipeptidyl sulfonamides possessing long-lasting intraocular pressure-lowering properties via the topical route.

  1999cited by this paper
• Carbonic anhydrase inhibitors — Part 52. Metal complexes of heterocyclic sulfonamides: A new class of strong topical intraocular pressure-lowering agents in rabbits

  1998cited by this paper
• The carbon dioxide hydration activity of carbonic anhydrase. I. Stop-flow kinetic studies on the native human isoenzymes B and C.

  1971cited by this paper

• Sulfonamide inhibitors of bacterial carbonic anhydrases.

  2024cites this paper
• Antibacterial carbonic anhydrase inhibitors: an update on the recent literature

  2020cites this paper
• Carbonic anhydrases from pathogens

  2019cites this paper
• Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors

  2018cites this paper
• 1 Amino Acids as Building Blocks for Carbonic 2 Anhydrase Inhibitors 3

  2018cites this paper
• Synthesis and human/bacterial carbonic anhydrase inhibition with a series of sulfonamides incorporating phthalimido moieties.

  2017cites this paper
• Carbonic Anhydrase from Porphyromonas Gingivalis as a Drug Target

  2017cites this paper
• Synthesis and carbonic anhydrase inhibition of a series of SLC-0111 analogs.

  2017cites this paper
• Anion inhibition profiles of the γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei responsible of melioidosis and highly drug resistant to common antibiotics.

  2017cites this paper
• Inhibition of Bacterial Carbonic Anhydrases as a Novel Approach to Escape Drug Resistance.

  2017cites this paper
• Stable and Sensitive Detection of Sulfonamide Residues in Animal-Derived Foods Using a Reproducible Surface Plasmon Resonance Immunosensor

  2017cites this paper
• Anion inhibition profiles of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum.

  2016cites this paper
• Anion inhibition profiles of α-, β- and γ-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae.

  2016cites this paper
• An Overview of the Carbonic Anhydrases from Two Pathogens of the Oral Cavity: Streptococcus mutans and Porphyromonas gingivalis.

  2016cites this paper
• Cloning, expression and purification of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum

  2016cites this paper
• New light on bacterial carbonic anhydrases phylogeny based on the analysis of signal peptide sequences

  2016cites this paper
• A failed tentative to design a super carbonic anhydrase having the biochemical properties of the most thermostable CA (SspCA) and the fastest (SazCA) enzymes

  2015cites this paper
• Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.

  2015cites this paper
• Cloning, characterization and anion inhibition studies of a new γ-carbonic anhydrase from the Antarctic bacterium Pseudoalteromonas haloplanktis.

  2015cites this paper
• Protonography, a powerful tool for analyzing the activity and the oligomeric state of the γ-carbonic anhydrase identified in the genome of Porphyromonas gingivalis.

  2015cites this paper
• Protonography, a technique applicable for the analysis of η-carbonic anhydrase activity

  2015cites this paper
• Bacterial, fungal and protozoan carbonic anhydrases as drug targets

  2015cites this paper
• Sulfonamide inhibition studies of the γ-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune.

  2015cites this paper
• Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV.

  2014cites this paper