Regulation of gene expression by the RNA-binding protein Sam68 in cancer.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Biochemical Society Transactions

• Publication date

  2008-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BST0360505PMID 18481990
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sam68 haploinsufficiency delays onset of mammary tumorigenesis and metastasis

  2008cited by this paper
• The RNA‐binding and adaptor protein Sam68 modulates signal‐dependent splicing and transcriptional activity of the androgen receptor

  2008cited by this paper
• Targeting the RNA-binding protein Sam68 as a treatment for cancer?

  2007cited by this paper
• The RNA-binding protein Sam68 contributes to proliferation and survival of human prostate cancer cells

  2007cited by this paper
• SUMO modification of Sam68 enhances its ability to repress cyclin D1 expression and inhibits its ability to induce apoptosis

  2006cited by this paper
• The human SWI/SNF subunit Brm is a regulator of alternative splicing

  2006cited by this paper
• Tyrosine Phosphorylation of Sam68 by Breast Tumor Kinase Regulates Intranuclear Localization and Cell Cycle Progression*

  2005cited by this paper
• The RNA binding protein Sam68 is acetylated in tumor cell lines, and its acetylation correlates with enhanced RNA binding activity

  2004cited by this paper
• Sam68 exerts separable effects on cell cycle progression and apoptosis

  2004cited by this paper
• Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.

  2003cited by this paper
• Sam68, the KH domain-containing superSTAR.

  2003cited by this paper
• Physical and functional interaction between the transcriptional cofactor CBP and the KH domain protein Sam68.

  2002cited by this paper
• Signal-dependent regulation of splicing via phosphorylation of Sam68

  2002cited by this paper
• Functional interaction of Sam68 and heterogeneous nuclear ribonucleoprotein K

  2002cited by this paper
• Inhibition of HIV replication by dominant negative mutants of Sam68, a functional homolog of HIV-1 Rev

  1999cited by this paper
• Specificity and Determinants of Sam68 RNA Binding

  1997cited by this paper

• Role of Sam68 in Sunitinib induced renal cell carcinoma apoptosis

  2022cites this paper
• The function and regulatory mechanism of RNA-binding proteins in breast cancer and their future clinical treatment prospects

  2022cites this paper
• Antibody-based biosensor to detect oncogenic splicing factor Sam68 for the diagnosis of lung cancer

  2020cites this paper
• The Oncogene Metadherin Interacts with the Known Splicing Proteins YTHDC1, Sam68 and T-STAR and Plays a Novel Role in Alternative mRNA Splicing

  2019cites this paper
• UNR/CSDE1 Expression Is Critical to Maintain Invasive Phenotype of Colorectal Cancer through Regulation of c-MYC and Epithelial-to-Mesenchymal Transition

  2019cites this paper
• Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNΔ7 mouse model of SMA

  2018cites this paper
• High expression of Sam68 in sacral chordomas is associated with worse clinical outcomes

  2017cites this paper
• Sam68 Is Required for DNA Damage Responses via Regulating Poly(ADP-ribosyl)ation

  2016cites this paper
• Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation

  2016cites this paper
• Sam68 regulates cell proliferation and cell adhesion‐mediated drug resistance (CAM‐DR) via the AKT pathway in non‐Hodgkin's lymphoma

  2015cites this paper
• Sam68 is cleaved by caspases under apoptotic cell death induced by ionizing radiation

  2015cites this paper
• Sam68 promotes cellular proliferation and predicts poor prognosis in esophageal squamous cell carcinoma

  2015cites this paper
• High Sam68 expression predicts poor prognosis in non-small cell lung cancer

  2014cites this paper
• Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

  2013cites this paper
• Sam68 modulates the promoter specificity of NF-κB and mediates expression of CD25 in activated T cells

  2013cites this paper
• Expression and distribution of Src in the nucleus of myocytes in cardiac hypertrophy.

  2013cites this paper
• The role of QKI-5 in CG4 oligodendrocyte differentiation

  2013cites this paper
• High expression level and nuclear localization of Sam68 are associated with progression and poor prognosis in colorectal cancer

  2013cites this paper
• Overexpression and cytoplasmic localisation of Sam68 correlates with tumour progression and poor prognosis in patients with clinically N0 oral tongue cancer

  2012cites this paper
• Versatility of RNA-Binding Proteins in Cancer

  2012cites this paper
• Global Analyses of Alternative Splicing in Evolution and Nervous System Development

  2012cites this paper
• miR-574-5p negatively regulates Qki6/7 to impact β-catenin/Wnt signalling and the development of colorectal cancer

  2012cites this paper
• Networking in a global world: establishing functional connections between neural splicing regulators and their target transcripts.

  2011cites this paper
• Splicing Programs and Cancer

  2011cites this paper
• MicroRNA regulation by RNA-binding proteins and its implications for cancer

  2011cites this paper
• Chromatin dynamics associated with HIV-1 Tat-activated transcription.

  2010cites this paper
• Bortezomib Induces the Formation of Nuclear poly(A) RNA Granules Enriched in Sam68 and PABPN1 in Sensory Ganglia Neurons

  2010influential citation
• The role of the RNA‐binding protein Sam68 in mammary tumourigenesis

  2010cites this paper
• STAR trek: An introduction to STAR family proteins and review of quaking (QKI).

  2010cites this paper
• ERK‐regulated differential expression of the Mitf 6a/b splicing isoforms in melanoma

  2010cites this paper
• The serine/arginine-rich protein SF2/ASF regulates protein sumoylation

  2010cites this paper
• Biochemical and Functional Analysis of -Protocadherin Intracellular Signaling Pathways

  2009cites this paper