Chitosan gels for the vaginal delivery of lactic acid: Relevance of formulation parameters to mucoadhesion and release mechanisms

No abstract is available for this paper.

• Publication year

  2008

• Venue

  AAPS PharmSciTech

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1208/pt0704104PMID 17285750PMCID PMC2750341
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mucoadhesive vaginal tablets as veterinary delivery system for the controlled release of an antimicrobial drug, acriflavine

  2008cited by this paper
• Swellable drug-polyelectrolyte matrices (SDPM). Characterization and delivery properties.

  2005cited by this paper
• In vivo distribution of a vaginal gel: MRI evaluation of the effects of gel volume, time and simulated intercourse.

  2004cited by this paper
• Development of Oral Controlled Release Tablet Formulations Based on Diltiazem–Carrageenan Complex

  2004cited by this paper
• Vaginal dryness assessment in postmenopausal women using pH test strip.

  2003cited by this paper
• Mucoadhesive vaginal tablets as veterinary delivery system for the controlled release of an antimicrobial drug, acriflavine

  2002cited by this paper
• Rheological evaluation of thermosensitive and mucoadhesive vaginal gels in physiological conditions.

  2002cited by this paper
• Antimicrobial components of vaginal fluid.

  2002cited by this paper
• Properties of a new acid-buffering bioadhesive vaginal formulation (ACIDFORM).

  2001cited by this paper
• Chitosan: some pharmaceutical and biological aspects ‐ an update

  2001cited by this paper
• Studies on gynaecological hydrophilic lactic acid preparations. Part 3: Effects of chitosan on the properties of methylcellulose gels.

  2000cited by this paper
• Studies on gynecological hydrophilic lactic acid preparations. Part 2 : Effects of Eudragit® E-100 on properties of methylcellulose gels

  1999cited by this paper
• A vaginal fluid simulant.

  1999cited by this paper
• Vaginal pH and parabasal cells in postmenopausal women.

  1999cited by this paper
• In vitro degradation study of polyester microspheres by a new HPLC method for monomer release determination.

  1998cited by this paper
• Water-soluble polycations as oral drug carriers (tablets).

  1997cited by this paper
• Characterization of rheological and mucoadhesive properties of three grades of chitosan hydrochloride.

  1997cited by this paper
• Comparative Rheomechanical and Adhesive Properties of Two Hydrocolloid Dressings: Dependence on the Degree of Hydration

  1996cited by this paper
• Chitosan hydrogel as a base for semisolid drug forms

  1993cited by this paper
• Hydrocolloids and gels of chitosan as drug carriers

  1993cited by this paper
• In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers

  1992cited by this paper
• Bacterial vaginosis and the effect of intermittent prophylactic treatment with an acid lactate gel.

  1990cited by this paper
• The relation between vaginal pH and the microbiological status in vaginitis

  1985cited by this paper

• Engineering Poly(lactic Acid)-Based Scaffolds for Abundant, Sustained, and Prolonged Lactate Release

  2025cites this paper
• Smart lactate delivery from electro-responsive electrospun fibers

  2025cites this paper
• Vaginal Sheets with Thymbra capitata Essential Oil for the Treatment of Bacterial Vaginosis: Design, Characterization and In Vitro Evaluation of Efficacy and Safety

  2023cites this paper
• Enzymatic Degradation of Polylactic Acid Fibers Supported on a Hydrogel for Sustained Release of Lactate.

  2023cites this paper
• Immediate-sustained lactate release using alginate hydrogel assembled to proteinase K/polymer electrospun fibers.

  2023cites this paper
• A Novel Approach for the Treatment of Aerobic Vaginitis: Azithromycin Liposomes-in-Chitosan Hydrogel

  2023cites this paper
• Smart redox-sensitive micelles based on chitosan for dasatinib delivery in suppressing inflammatory diseases.

  2022cites this paper
• Manufacturing and Examination of Vaginal Drug Delivery System by FDM 3D Printing

  2021cites this paper
• Chitosan and Aloe vera gel formulations as wound healing agents in episiotomy

  2021cites this paper
• Recent Advances in Polymer-Based Vaginal Drug Delivery Systems

  2021cites this paper
• Chitosan-based systems aimed at local application for vaginal infections.

  2021cites this paper
• Understanding Electrodeposition of Chitosan–Hydroxyapatite Structures for Regeneration of Tubular-Shaped Tissues and Organs

  2021cites this paper
• Development and microbiological evaluation of chitosan and chitosan-alginate microspheres for vaginal administration of metronidazole.

  2021cites this paper
• Investigation of Parameters Influencing Tubular-Shaped Chitosan-Hydroxyapatite Layer Electrodeposition

  2020cites this paper
• lSodium bicarbonate gels: a new promising strategy for the treatment of vulvovaginal candidosis.

  2020cites this paper
• Hydrogels as intrinsic antimicrobials

  2020cites this paper
• Chitosan, N,N,N-trimethyl chitosan (TMC) and 2-hydroxypropyltrimethyl ammonium chloride chitosan (HTCC): The potential immune adjuvants and nano carriers.

  2020cites this paper
• Vaginal Bioadhesive Drug Delivery Systems and Their Applications

  2020cites this paper
• Novel amphiphilic chitosan micelles as carriers for hydrophobic anticancer drugs.

  2020cites this paper
• Pulmonary Bioadhesive Drug Delivery Systems and Their Applications

  2020cites this paper
• Influence of chitosan average molecular weight on degradation and stability of electrodeposited conduits.

  2020cites this paper
• Development and in vivo evaluation of chitosan-gel containing Mitracarpus frigidus methanolic extract for vulvovaginal candidiasis treatment.

  2020cites this paper
• Transnasal nimodipine-loaded mucoadhesive nanoliposomes: Preparation and in-vitro evaluation

  2019cites this paper
• Localized Therapy of Vaginal Infections and Inflammation: Liposomes-In-Hydrogel Delivery System for Polyphenols

  2019influential citation
• Nanocarriers Based Novel Drug Delivery as Effective Drug Delivery: A Review

  2019cites this paper
• Polymeric gels for intravaginal drug delivery

  2018cites this paper
• Chitosan Loaded into a Hydrogel Delivery System as a Strategy to Treat Vaginal Co-Infection

  2018cites this paper
• Characterization and microbiological evaluation of chitosan-alginate microspheres for cefixime vaginal administration.

  2018cites this paper
• Pharmaceutical Delivery Systems Composed of Chitosan

  2017cites this paper
• Vaginal semisolid products: Technological performance considering physiologic parameters

  2017influential citation
• Mucoadhesive polymers in the treatment of dry X syndrome.

  2016cites this paper
• Once Daily In-Situ Forming Versus Twice-Daily Conventional Metronidazole Vaginal Gels for Treatment of Bacterial Vaginosis: A Randomized Controlled Trial

  2016cites this paper
• In vitro evaluation of some parameters involved in mucoadhesion of aqueous polymeric dispersions

  2015cites this paper
• Mucoadhesive and thermogelling systems for vaginal drug delivery.

  2015cites this paper
• New strategies for local treatment of vaginal infections.

  2015cites this paper
• CHITOSAN: A MULTIFACET POLYMER Review Article

  2015cites this paper
• Recent advances on anti-HIV vaginal delivery systems development.

  2015cites this paper
• CHITOSAN: A MULTIFACET POLYMER

  2015cites this paper
• Ionic polymeric micelles based on chitosan and fatty acids and intended for wound healing. Comparison of linoleic and oleic acid.

  2014cites this paper
• Protein and oligonucleotide delivery systems for vaginal microbicides against viral STIs

  2014cites this paper
• Associations of natural polymers to modulate mucoadhesion of vaginal rinse-off and leave-on formulations

  2014cites this paper
• Therapeutic application of intrabodies against age-related neurodegenerative disorders.

  2014cites this paper
• In vitro liberation of indomethacin from chitosan gels containing microemulsion in different dissolution mediums.

  2014cites this paper
• Vaginal Mucosa and Drug Delivery

  2014cites this paper
• Chitosan-Based Nanomedicine for Rosmarinic Acid Ocular Delivery

  2014cites this paper
• Approaches of Novel drug delivery systems for Anti-HIV agents

  2014cites this paper
• Characterization of Commercially Available Vaginal Lubricants: A Safety Perspective

  2014cites this paper
• Transarterial chemoembolization of hepatocellular carcinoma – agents and drugs: an overview. Part 2

  2013cites this paper
• The effect of polymer coatings on physicochemical properties of spray-dried liposomes for nasal delivery of BSA.

  2013cites this paper
• Accelerated wound healing and anti-inflammatory effects of physically cross linked polyvinyl alcohol–chitosan hydrogel containing honey bee venom in diabetic rats

  2013cites this paper
• PERIODONTAL CHITOSAN-GELS DESIGNED FOR IMPROVED LOCAL INTRA-POCKET DRUG DELIVERY

  2013cites this paper
• Association of Thymbra capitata essential oil and chitosan (TCCH hydrogel): a putative therapeutic tool for the treatment of vulvovaginal candidosis†

  2013cites this paper
• Development of chitosan-coated liposomes for improved therapy of vaginal infections: clotrimazole as model drug

  2012cites this paper
• CHITOSAN: A PERFECT POLYMER USED IN FABRICATING GENE DELIVERY AND NOVEL DRUG DELIVERY SYSTEMS Review Article

  2012cites this paper
• Vaginal mucoadhesive drug delivery systems

  2012cites this paper
• The role of chitosan as a mucoadhesive agent in mucosal drug delivery

  2012cites this paper
• Innovative pharmaceutical formulations and excipients for nasal delivery of drugs to target the systemic circulation

  2012cites this paper
• Rheological and mechanical properties of poloxamer mixtures as a mucoadhesive gel base

  2011cites this paper
• MASTER THESIS FOR THE DEGREE MASTER OF PHARMACY DEVELOPMENT OF CHITOSAN-COATED LIPOSOMES FOR IMPROVED THERAPY OF VAGINAL INFECTIONS: CLOTRIMAZOLE AS MODEL

  2011cites this paper
• Bacterial vaginosis: Etiology and modalities of treatment—A brief note

  2011cites this paper
• CHARACTERIZING FORMULATIONS CONTAINING DERIVATIZED CHITOSAN WITH POLYMER BLENDING

  2011cites this paper
• New solid mucoadhesive systems for benzydamine vaginal administration.

  2011cites this paper
• Treatment of blood flow abnormality using mucosal delivery of nitric oxide

  2011cites this paper
• Antifungal activity of low molecular weight chitosan against clinical isolates of Candida spp.

  2010cites this paper
• Development Of Biopolymeric Suppositories For The Treatment Of Bacterial Vaginosis

  2010cites this paper
• A poloxamer/chitosan in situ forming gel with prolonged retention time for ocular delivery.

  2010cites this paper
• Strategies to prolong the intravaginal residence time of drug delivery systems.

  2009cites this paper
• Chitosan and its salts for mucosal and transmucosal delivery

  2009cites this paper
• Targeting pharmacons to the brain via the nasal pathway

  2009cites this paper
• In vitro and ex vivo bioadhesivity analysis of polymeric intravaginal caplets using physicomechanics and computational structural modeling.

  2009cites this paper
• Formulation studies of benzydamine mucoadhesive formulations for vaginal administration

  2009cites this paper
• Polymer-lipid based mucoadhesive microspheres prepared by spray-congealing for the vaginal delivery of econazole nitrate.

  2009cites this paper
• Sodium hyaluronate as a mucoadhesive component in nasal formulation enhances delivery of molecules to brain tissue.

  2009cites this paper
• BIOLOGICAL RESEARCH CENTER OF THE HUNGARIAN

  2009cites this paper
• Chitosan citrate as multifunctional polymer for vaginal delivery. Evaluation of penetration enhancement and peptidase inhibition properties.

  2008cites this paper
• Mucoadhesive drug carriers and polymers for effective drug delivery

  2008cites this paper
• DEVELOPMENT AND EVALUATION OF LIPOSOMAL MUCOADHESIVE GEL FOR NASAL DELIVERY OF ACYCLOVIR

  2008cites this paper
• MUKOADEZİF POLİMERLERLE ANTİFUNGAL ETKİLİ VAJİNAL TABLET FORMÜLASYONLARININ GELİŞTİRİLMESİ

  2008cites this paper
• Wound healing and anti-inflammatory activities of bee venom-chitosan blend films

  2008cites this paper
• NATURAL ANTIMICROBIALS AND THEIR ROLE IN VAGINAL HEALTH: A SHORT REVIEW.

  2008cites this paper
• Effect of Thiolated Polymers to Textural and Mucoadhesive Properties of Vaginal Gel Formulations Prepared with Polycarbophil and Chitosan

  2008cites this paper
• A Review of Current Intravaginal Drug Delivery Approaches Employed for the Prophylaxis of HIV/AIDS and Prevention of Sexually Transmitted Infections

  2008cites this paper
• Performance of an in vitro mucoadhesion testing method for vaginal semisolids: influence of different testing conditions and instrumental parameters.

  2008cites this paper
• FORMULATION AND EVALUATION OF VAGINAL GEL USING SPILLANTHUS CILIATA FOR THE TREATMENT OF MENSTRUAL PAIN

  year unknowncites this paper