Gap junction-dependent and -independent EDHF-type relaxations may involve smooth muscle cAMP accumulation.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Physiology. Heart and Circulatory Physiology

• Publication date

  2002-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/AJPHEART.00903.2001PMID 11893592
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Relative contributions of NO and gap junctional communication to endothelium-dependent relaxations of rabbit resistance arteries vary with vessel size.

  2002cited by this paper
• EDHF – are there gaps in the pathway?

  2001influential reference
• Gap junction-dependent increases in smooth muscle cAMP underpin the EDHF phenomenon in rabbit arteries.

  2001cited by this paper
• Dihydroxyeicosatrienoic acids are potent activators of Ca2+‐activated K+ channels in isolated rat coronary arterial myocytes

  2001cited by this paper
• Adenylyl cyclase isoforms and signal integration in models of vascular smooth muscle cells.

  2001cited by this paper
• Characterization of adenylyl cyclase isoforms in rat peripheral pulmonary arteries.

  2001cited by this paper
• Short- and long-term regulation of rat carotid body gap junctions by cAMP. Identification of connexin43, a gap junction subunit.

  2000cited by this paper
• Incidence of myoendothelial gap junctions in the proximal and distal mesenteric arteries of the rat is suggestive of a role in endothelium-derived hyperpolarizing factor-mediated responses.

  2000cited by this paper
• Clustering of connexin 43-enhanced green fluorescent protein gap junction channels and functional coupling in living cells.

  2000cited by this paper
• Endothelial cell pathway for conduction of hyperpolarization and vasodilation along hamster feed artery.

  2000cited by this paper
• Mechanism and signal transduction of 14 (R), 15 (S)-epoxyeicosatrienoic acid (14,15-EET) binding in guinea pig monocytes.

  2000cited by this paper
• Comparison of glycyrrhetinic acid isoforms and carbenoxolone as inhibitors of EDHF-type relaxations mediated via gap junctions.

  2000cited by this paper
• Role of phospholipase A(2) and myoendothelial gap junctions in melittin-induced arterial relaxation.

  2000cited by this paper
• Nitric oxide-independent relaxations to acetylcholine and A23187 involve different routes of heterocellular communication. Role of Gap junctions and phospholipase A2.

  1999cited by this paper
• Role of heterocellular Gap junctional communication in endothelium-dependent smooth muscle hyperpolarization: inhibition by a connexin-mimetic peptide.

  1999cited by this paper
• Cyclic AMP mediates EDHF-type relaxations of rabbit jugular vein.

  1999cited by this paper
• Endothelium‐derived hyperpolarizing factor but not NO reduces smooth muscle Ca2+ during acetylcholine‐induced dilation of microvessels

  1999cited by this paper
• Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonic acid in the regulation of tone.

  1999cited by this paper
• Information Networks in the Arterial Wall.

  1999cited by this paper
• Regulation of adenylyl cyclase type V/VI in smooth muscle: interplay of inhibitory G protein and Ca2+ influx.

  1998cited by this paper
• Cytochrome P450: a novel system modulating Ca2+ channels and contraction in mammalian heart cells

  1998cited by this paper
• Adaptation in cyclic AMP signalling processes: a central role for cyclic AMP phosphodiesterases.

  1998cited by this paper
• Inhibition of the gap junctional component of endothelium‐dependent relaxations in rabbit iliac artery by 18‐α glycyrrhetinic acid

  1998cited by this paper
• Central role of heterocellular gap junctional communication in endothelium‐dependent relaxations of rabbit arteries

  1998cited by this paper
• Gap junctions in vascular smooth muscle.

  1998cited by this paper
• Bioassay of an Endothelium-Derived Hyperpolarizing Factor from Bovine Coronary Arteries: Role of a Cytochrome P450 Metabolite

  1998cited by this paper
• Nitric oxide is the mediator of both endothelium-dependent relaxation and hyperpolarization of the rabbit carotid artery.

  1997cited by this paper
• A transferable, beta‐naphthoflavone‐inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells.

  1996cited by this paper
• Multiple pathways underlying endothelium‐dependent relaxation in the rabbit isolated femoral artery

  1995cited by this paper
• Structure and function of cyclic nucleotide-dependent protein kinases.

  1994cited by this paper
• Simultaneous measurement of vasodilation and changes in cyclic nucleotides in the perfused mesenteric arterial bed of the rat.

  1993cited by this paper
• Polycystic disease of the kidneys complicating the diagnosis of myocardial echinococcosis.

  1993cited by this paper
• Modulation of vascular cyclic nucleotide phosphodiesterases by cyclic GMP: role in vasodilatation.

  1993cited by this paper
• Effect of Ca2+ ionophores on membrane potential of pig coronary artery endothelial cells.

  1992cited by this paper

• Therapeutic potential of phosphodiesterase inhibitors for endothelial dysfunction-related diseases.

  2020cites this paper
• Cell-to-Cell Communication and Signaling Pathways Myoendothelial gap junctions mediate regulation of angiopoietin-2-induced vascular hyporeactivity after hypoxia through connexin 43-gated cAMP transfer

  2017cites this paper
• Running head : MEGJ mediate regulation of Ang 2 on vascular hyporeactivity 8 Corresponding author :

  2017cites this paper
• The influence of silica nanoparticles on small mesenteric arterial function.

  2016cites this paper
• The influence of nanomaterial uptake on small arterial function

  2015cites this paper
• Interactions between thromboxane A₂, thromboxane/prostaglandin (TP) receptors, and endothelium-derived hyperpolarization.

  2014cites this paper
• Tudor Griffith, Gap Junctions and Conducted Vasodilatation: Electromechanical Coupling Back in the Limelight

  2013cites this paper
• Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca2+‐sensitive K+ channels in rat mesenteric artery

  2013cites this paper
• Influence of oxygen on vascular tone during acute hypoxia

  2013cites this paper
• Glomerular expression of connexin 40 and connexin 43 in rat experimental glomerulonephritis

  2013cites this paper
• Endothelium-derived relaxing factor-mediated vasodilation in mouse mesenteric vascular beds.

  2012cites this paper
• Endothelium-derived hyperpolarizing factor and diabetes.

  2011cites this paper
• Cyclic nucleotide-dependent relaxation pathways in vascular smooth muscle

  2011cites this paper
• Modulation of endothelium-dependent arterial relaxation by inorganic arsenic and glucose

  2010cites this paper
• [Therapeutic target for endothelium-derived hyperpolarizing factor signaling in diabetic vascular complication].

  2010cites this paper
• REGULATORY EFFECTS OF MYOENDOTHELIAL GAP JUNCTION ON VASCULAR REACTIVITY AFTER HEMORRHAGIC SHOCK IN RATS

  2009cites this paper
• Functional role of gap junctions in cytokine-induced leukocyte adhesion to endothelium in vivo.

  2008cites this paper
• Attenuation of nitric oxide- and prostaglandin-independent vasodilation of retinal arterioles induced by acetylcholine in streptozotocin-treated rats.

  2007cites this paper
• arteries from aged OLETF rats, a model of Type 2 diabetes Imbalance between endothelium-derived relaxing and contracting factors in mesenteric

  2007cites this paper
• Expressing a Single-Nucleotide Variant of Human Adenylyl Cyclase 6 Increased Enzyme Activity and {beta}-Adrenergic Mediated Vasodilation in Subjects

  2007cites this paper
• Endothelial dysfunction in insulin resistance : the role of EDHF and gap junction communication

  2007cites this paper
• C-type natriuretic peptide: a new endothelium-derived hyperpolarizing factor?

  2007cites this paper
• The significance of endothelium-derived hyperpolarizing factor in the human circulation.

  2007cites this paper
• [A therapeutic target for microvascular complications in diabetes].

  2006cites this paper
• Mechanisms underlying the impaired EDHF-type relaxation response in mesenteric arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats.

  2006cites this paper
• Inhibition of acetylcholine-induced EDHF response by elevated glucose in rat mesenteric artery.

  2005cites this paper
• Cilostazol improves endothelium-derived hyperpolarizing factor-type relaxation in mesenteric arteries from diabetic rats.

  2005cites this paper
• Functional changes in adenylyl cyclases and associated decreases in relaxation responses in mesenteric arteries from diabetic rats.

  2005cites this paper
• Endothelium‐dependent smooth muscle hyperpolarization: do gap junctions provide a unifying hypothesis?

  2004cites this paper
• Angiotensin II receptor blockade corrects altered expression of gap junctions in vascular endothelial cells from hypertensive rats.

  2004cites this paper
• Vascular gap junctions and implications for hypertension

  2004cites this paper
• Factors, fiction and endothelium‐derived hyperpolarizing factor

  2004cites this paper
• Factors , fiction and endothelium-derived hyperpolarizing factor-EDH ( F )

  2004cites this paper
• Enhanced inhibition of the EDHF phenomenon by a phenyl methoxyalaninyl phosphoramidate derivative of dideoxyadenosine

  2004influential citation
• The obligatory link: role of gap junctional communication in endothelium-dependent smooth muscle hyperpolarization.

  2004cites this paper
• Hydrogen Peroxide, an Endogenous Endothelium-Derived Hyperpolarizing Factor, Plays an Important Role in Coronary Autoregulation In Vivo

  2003cites this paper
• Hyperthyroidism enhances endothelium-dependent relaxation in the rat renal artery.

  2003cites this paper
• Distinct hyperpolarizing and relaxant roles for gap junctions and endothelium-derived H2O2 in NO-independent relaxations of rabbit arteries

  2003cites this paper
• Essential Role of Gap Junctions in NO- and Prostanoid-Independent Relaxations Evoked by Acetylcholine in Rabbit Intracerebral Arteries

  2003cites this paper
• Alterations in EDHF-type relaxation and phosphodiesterase activity in mesenteric arteries from diabetic rats.

  2003cites this paper
• cAMP facilitates EDHF-type relaxations in conduit arteries by enhancing electrotonic conduction via gap junctions

  2002cites this paper
• Involvement of Myoendothelial Gap Junctions in the Actions of Endothelium-Derived Hyperpolarizing Factor

  2002cites this paper