Procollagen: Conversion of the Precursor to Collagen by a Neutral Protease

No abstract is available for this paper.

• Publication year

  1972

• Venue

  Science

• Publication date

  1972-02-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1126/science.175.4021.544PMID 5008597
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The nature of the collagen synthesized by cultured human fibroblasts.

  1971cited by this paper
• Evidence for procollagen, a biosynthetic precursors of collagen.

  1971cited by this paper
• Studies on protocollagen: identification of a precursor of proto alpha 1.

  1971cited by this paper
• Studies on protocollagen: Identification of a precursor of proto α1

  1971cited by this paper
• Collagen synthesis on polysomes in vivo and in vitro.

  1971cited by this paper
• Biosynthesis of the alpha chains of collagen studied by pulse-labeling in culture.

  1970cited by this paper
• Biosynthesis of the α Chains of Collagen Studied by Pulse-labeling in Culture

  1970cited by this paper
• The Limited Cleavage of Native Collagen with Chymotrypsin, Trypsin, and Cyanogen Bromide

  1966cited by this paper

• Advanced application of collagen-based biomaterials in tissue repair and restoration

  2022cites this paper
• Tendon Extracellular Matrix Assembly, Maintenance and Dysregulation Throughout Life.

  2021cites this paper
• Recent advances in the use of serological bone formation markers to monitor callus development and fracture healing.

  2010cites this paper
• Is the tendon embryogenesis process resurrected during tendon healing?

  2003cites this paper
• Identification and Characterization of the In Vitro Synthesized Gene Products of Bacteriophage M 13

  2003cites this paper
• Chapter Eight Mapping the Structure of Science

  1999cites this paper
• Extracellular matrix 1: Fibril-forming collagens.

  1995cites this paper
• Proteolytic mechanisms of cartilage breakdown: a target for arthritis therapy?

  1995cites this paper
• Extracellular matrix. 1: fibril-forming collagens.

  1994cites this paper
• Feedback Regulation of Collagen Synthesis

  1986cites this paper
• Collagen Grafts—Here Today and Gone Tomorrow

  1986cites this paper
• Gene Action Changes during Nonvertebrate Differentiation

  1983cites this paper
• 5 – Collagen Biosynthesis and Degradation

  1982cites this paper
• Effect of teratogens on connective tissue development

  1982cites this paper
• Initiation of fibroin biosynthesis. I. Isolation of nascent fibroin peptides from the posterior silk gland of Bombyx mori.

  1981cites this paper
• Detection of Cell-Associated Aminoterminal Procollagen Peptidase Activity in Cultured Fibroblasts

  1981cites this paper
• Sequential events in the formation of collagen secretion granules with special reference to the development of segment‐long‐spacing‐like aggregates

  1981cites this paper
• Functions and regulations of cellular proteinases during growth and differentiation of the cellular slime mold Dictyostelium discoideum

  1980cites this paper
• 4 – The Chemistry and Biology of Collagen

  1979cites this paper
• Tendon collagen fibrillogenesis: intracellular subassemblies and cell surface changes associated with fibril growth.

  1979cites this paper
• Procollagen propeptide release by procollagen peptidases and bacterial collagenase.

  1979cites this paper
• Separate amino and carboxyl procollagen peptidases in chick embryo tendon.

  1979cites this paper
• Partial purification and characterization of a neutral protease which cleaves the N-terminal propeptides from procollagen.

  1978cites this paper
• The role of glycosylation in the enzymatic conversion of procollagen to collagen: studies using tunicamycin and concanavalin A.

  1978cites this paper
• A new method for obtaining barnacle cement in the liquid state for polymerization studies

  1977cites this paper
• Biosynthesis of type II collagen. Removal of amino-and carboxy-terminal extensions from procollagen synthesized by chick embryo cartilage cells.

  1977cites this paper
• Centrosymmetrical cross-banded structures in the matrix of rat incisor predentin and dentin.

  1977cites this paper
• A direct assay for collagen synthesis based on the estimation of collagenase-derived N-glycyl peptides.

  1977cites this paper
• Intermediates in the conversion of procollagen to collagen. Evidence for stepwise limited proteolysis of the COOH-terminal peptide extensions.

  1977cites this paper
• Alterations in the Metabolism of Glycosaminoglycans and Collagen

  1977cites this paper
• A Co-Citation Model of a Scientific Specialty: A Longitudinal Study of Collagen Research

  1977cites this paper
• Biosynthesis of collagen and its alterations in pathological states.

  1976cites this paper
• Removal of amino-terminal and carboxy-terminal extension peptides from procollagen during synthesis of chick embryo tendon collagen.

  1976cites this paper
• Intracellular protein degradation in mammalian and bacterial cells: Part 2.

  1976cites this paper
• Biochemical characteristics and biological significance of the genetically-distinct collagens

  1976cites this paper
• Carbohydrate moieties of procollagen: incorporation of isotopically labeled mannose and glucosamine into propeptides of procollagen secreted by matrix-free chick embryo tendon cells.

  1976cites this paper
• Defects in the biochemistry of collagen in diseases of connective tissue.

  1976cites this paper
• Intracellular Steps in the Biosynthesis of Collagen

  1976cites this paper
• Effects of lead on collagen synthesis and renal function in the rat

  1976cites this paper
• Structure and Biosynthesis of collagen

  1975cites this paper
• Intermediates in the limited proteolytic conversion of procollagen to collagen.

  1975cites this paper
• Procollagen peptidase: its mode of action on the native substrate.

  1975cites this paper
• Afibrillar dental cementum in the rat and hamster.

  1975cites this paper
• Connective tissue cells, cell proliferation and synthesis of extracellular matrix-a review.

  1975cites this paper
• Afibrillar dental cementum in the rat and hamster.

  1975cites this paper
• Collagen biosynthesis.

  1975cites this paper
• Identification and characterization of the in vitro synthesized gene products of bacteriophage M13

  1975cites this paper
• The relation between connective tissue cells and intercellular substances, including basement membranes.

  1975cites this paper
• The metabolic requirements for transcellular movement and secretion of collagen.

  1975cites this paper
• Biosynthesis of collagen. The biochemist's view.

  1974cites this paper
• Hydroxylation of lysyl residues in native and denatured protocollagen by protocollagen lysyl hydroxylase in vitro.

  1974cites this paper
• Intracellular hydroxylation of non-helical protocollagen to form triple-helical procollagen and subsequent secretion of the molecule.

  1974cites this paper
• Isolation and characterization of the cyanogen bromide peptides from the alpha 1(3) chain of human collagen.

  1974cites this paper
• Prolyl hydroxylase.

  1974cites this paper
• Biosynthese und Alterung von Kollagen

  1974cites this paper
• Collagen fibrillogenesis in vitro: an accelerative effect of surfactants on collagen fibril formation.

  1974cites this paper
• The timecourse of collagen cross-linking.

  1974cites this paper
• The structure and assembly of procollagen - a review.

  1974cites this paper
• Influence of ascorbic acid on ribosomal patterns and collagen biosynthesis in healing wounds of scorbutic guinea pigs.

  1974cites this paper
• Collagen: Its structure and function in normal and pathological connective tissues.

  1974cites this paper
• A hereditary dysplasia of collagen tissues in sheep

  1974cites this paper
• Electron microscopic studies of procollagen from cultured human fibroblasts

  1974cites this paper
• The biosynthesis of collagen.

  1974cites this paper
• A constitutional disorder of connective tissue suggesting a defect in collagen biosynthesis

  1974cites this paper
• Biosynthesis and metabolism of collagen and its role in tissue repair processes.

  1974cites this paper
• Calf tendon procollagen peptidase: its purification and endopeptidase mode of action.

  1974cites this paper
• 4 – The Dermis*

  1974cites this paper
• Characterization of the pro 1 chain of procollagen. Isolation of a sequence unique to the precursor chain.

  1973cites this paper
• Rate of helix formation by intracellular procollagen and protocollagen. Evidence for a role for disulfide bonds.

  1973cites this paper
• Procollagen-a precursor form of collagen.

  1973cites this paper
• Collagen and procollagen production by a clonal line of Schwann cells.

  1973cites this paper
• THE DEVELOPMENTAL BIOLOGY OF VERTEBRATE COLLAGENS

  1973cites this paper
• Evidence for an amino-terminal extension in high-molecular-weight collagens from mature bovine skin.

  1973cites this paper
• Structure and biosynthesis of basement membranes.

  1973cites this paper
• Metabolic pathways and control mechanisms involved in the biosynthesis and turnover of collagen in normal and pathological connective tissues.

  1973cites this paper
• Subunit heterogeneity of thyroglobulin.

  1973cites this paper
• Biochemistry of the renal glomerular basement membrane and its alterations in diabetes mellitus.

  1973cites this paper
• Acquisition of three-dimensional structure of proteins.

  1973cites this paper
• A study on the conversion of procollagen. Release and recovery of procollagen peptides in the culture medium.

  1973cites this paper
• The immunology of procollagen. I. Development of antibodies to determinants unique to the proalpha l chain.

  1973cites this paper
• Defect in Conversion of Procollagen to Collagen in a Form of Ehlers-Danlos Syndrome

  1973cites this paper
• Human procollagen I. An anionic tropocollagen precursor from skin fibroblasts in culture.

  1973cites this paper
• Secretion and extracellular processing of procollagen by cultured human fibroblasts.

  1973cites this paper
• Structural characterization of a soluble fraction from lens-capsule basement membrane.

  1973cites this paper
• Identification of a disulfide-linked procollagen as the biosynthetic precursor of chick-bone collagen.

  1973cites this paper
• The production and secretion of procollagen peptidase by human fibroblasts in culture.

  1973cites this paper
• Glycoproteins.

  1973cites this paper
• Homeostasis in extracellular tissues: insights from studies on collagen.

  1973cites this paper
• Controls of connective tissue synthesis: collagen metabolism.

  1972cites this paper
• Precursors of collagen secreted by cultured human fibroblasts.

  1972cites this paper
• Structure and metabolism of connective 801 tissue proteins.

  1972cites this paper
• Microtubules in transcellular movement of procollagen.

  1972cites this paper
• Kinetic energy: saltation.

  1972cites this paper
• Characterization of the pro- 1 chain of procollagen.

  1972cites this paper
• Evidence for an Amino-Terminal Extension in High-Molecular-Weight Coliagens from Mature Bovine Skin ( procollagen / biosynthetic precursors / fibril formation / renaturation / electron microscopy )

  year unknowncites this paper