Cloning of subunits of convulxin, a collagen-like platelet-aggregating protein from Crotalus durissus terrificus venom.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Biochemical Journal

• Publication date

  1998-07-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1042/BJ3330389PMID 9657980PMCID PMC1219597
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Convulxin, a potent platelet-aggregating protein from Crotalus durissus terrificus venom, specifically binds to platelets.

  1997cited by this paper
• Adhesion and activation of human platelets induced by convulxin involve glycoprotein VI and integrin alpha2beta1.

  1997cited by this paper
• Amino acid sequence of the alpha subunit and computer modelling of the alpha and beta subunits of echicetin from the venom of Echis carinatus (saw-scaled viper).

  1997cited by this paper
• Molecular cloning and expression of bothrojaracin, a potent thrombin inhibitor from snake venom.

  1997cited by this paper
• Platelet Activation and Signal Transduction by Convulxin, a C-type Lectin from Crotalus durissus terrificus (Tropical Rattlesnake) Venom via the p62/GPVI Collagen Receptor*

  1997cited by this paper
• A Novel Association of Fc Receptor γ-Chain with Glycoprotein VI and Their Co-expression as a Collagen Receptor in Human Platelets*

  1997cited by this paper
• Structure of coagulation factors IX/X-binding protein, a heterodimer of C-type lectin domains

  1997cited by this paper
• cDNA cloning of IX/X-BP, a heterogeneous two-chain anticoagulant protein from snake venom.

  1996cited by this paper
• Amino acid sequence of a lectin-like protein from Lachesis muta stenophyrs venom.

  1996cited by this paper
• Binding of a novel 50-kilodalton alboaggregin from Trimeresurus albolabris and related viper venom proteins to the platelet membrane glycoprotein Ib-IX-V complex. Effect on platelet aggregation and glycoprotein Ib-mediated platelet activation.

  1996cited by this paper
• Primary structure of alboaggregin-B purified from the venom of Trimeresurus albolabris.

  1996cited by this paper
• Isolation, characterization and amino acid sequence of echicetin beta subunit, a specific inhibitor of von Willebrand factor and thrombin interaction with glycoprotein Ib.

  1994cited by this paper
• A simple PCR method for screening cDNA libraries.

  1994cited by this paper
• PCR: Methods and applications: editor Judy Cuddihy, Cold Spring Harbor Laboratory Press. US $55.00, R.O.W. $65.00 (personal); US $170.00, R.O.W. $180.00 (institutional)

  1993cited by this paper
• Primary structure of two-chain botrocetin, a von Willebrand factor modulator purified from the venom of Bothrops jararaca.

  1993cited by this paper
• MUST, a computer package of Management Utilities for Sequences and Trees.

  1993cited by this paper
• Electron microscopic cytochemistry on the distribution of wheat germ agglutinin receptor on the platelet plasma membrane after treatment with convulxin isolated from Crotalus durissus terrificus venom.

  1992cited by this paper
• Complete primary structure of a galactose-specific lectin from the venom of the rattlesnake Crotalus atrox. Homologies with Ca2(+)-dependent-type lectins.

  1991cited by this paper
• The primary structure of coagulation factor IX/factor X-binding protein isolated from the venom of Trimeresurus flavoviridis. Homology with asialoglycoprotein receptors, proteoglycan core protein, tetranectin, and lymphocyte Fc epsilon receptor for immunoglobulin E.

  1991cited by this paper
• The asialoglycoprotein receptor: a model for endocytic transport receptors.

  1990cited by this paper
• Two distinct classes of carbohydrate-recognition domains in animal lectins.

  1988cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Isolation and characterization of the alpha and beta subunits of the platelet-activating glycoprotein from the venom of Crotalus durissus cascavella.

  1985cited by this paper
• Subunit structure of a potent platelet-activating glycoprotein isolated from the venom of Crotalus durissus cascavella.

  1984cited by this paper
• Lectins: Biology, Biochemistry, Clinical Biochemistry

  1983cited by this paper
• I--isolation and electron microscope studies of a potent platelet-aggregating glycoprotein from the venom of Crotalus durissus cascavella.

  1983cited by this paper
• Convulxin-induced activation of intact and of thrombin-degranulated rabbit platelets: specific crossed desensitisation with collagen.

  1983cited by this paper
• Activation of guinea-pig platelets induced by convulxin, a substance extracted from the venom of Crotalus durissus cascavella.

  1980cited by this paper

• Promucetin, a new C-type lectin-like protein modulates coagulation by activating platelets via GPIb

  2025cites this paper
• Seasonality in Crotalus durissus venom.

  2024cites this paper
• Snake venom toxins targeting the central nervous system

  2022cites this paper
• Inflammasome NLRP3 activation induced by Convulxin, a C-type lectin-like isolated from Crotalus durissus terrificus snake venom

  2022cites this paper
• An integrative view of the toxic potential of Conophis lineatus (Dipsadidae: Xenodontinae), a medically relevant rear-fanged snake.

  2021cites this paper
• Progress Towards a Glycoprotein VI Modulator for the Treatment of Thrombosis.

  2020cites this paper
• Comparative proteomic profiling and functional characterization of venom pooled from captive crotalus durissus terrificus specimens and the Brazilian crotalic reference venom.

  2020cites this paper
• Clinical, Laboratory, and Therapeutic Aspects of Crotalus durissus (South American Rattlesnake) Victims: A Literature Review

  2019cites this paper
• Toxins Are an Excellent Source of Therapeutic Agents against Cardiovascular Diseases

  2018cites this paper
• Purification and characterization of Cc-Lec, C-type lactose-binding lectin: A platelet aggregation and blood-clotting inhibitor from Cerastes cerastes venom.

  2017cites this paper
• Convulxin, a C‐type lectin‐like protein, inhibits HCASMCs functions via WAD‐motif/integrin‐&agr;v interaction and NF‐&kgr;B‐independent gene suppression of GRO and IL‐8

  2017cites this paper
• Metalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction Sites

  2016cites this paper
• Cytotoxic Effects of Snake Venoms

  2016cites this paper
• Crotalus durissus venom: biological effects and relevant applications

  2016cites this paper
• Non-enzymatic proteins from snake venoms: a gold mine of pharmacological tools and drug leads.

  2013cites this paper
• megakaryocyte differentiation Expression of the collagen receptor glycoprotein VI during

  2013cites this paper
• C-type lectin-like proteins from snake venoms.

  2012cites this paper
• Cloning of cDNAs and molecular characterisation of C-type lectin-like proteins from snake venoms.

  2012cites this paper
• Snaclecs (Snake C-Type Lectins) that Activate Platelets

  2010cites this paper
• Snaclecs (snake C-type lectins) that inhibit or activate platelets by binding to receptors.

  2010cites this paper
• The Biologic Activity of Aggretin/Rhodocytin, a Snake Venom C-Type Lectin Protein (Snaclec)

  2010cites this paper
• The Field of Reptile Toxinology: Snakes, Lizards, and Their Venoms

  2009cites this paper
• Reptile C-type lectins.

  2009cites this paper
• C-type lectin protein isoforms of Macrovipera lebetina: cDNA cloning and genetic diversity.

  2009cites this paper
• Convulxin forms a dimer in solution and can bind eight copies of glycoprotein VI: implications for platelet activation.

  2009cites this paper
• Crotalus durissus collilineatus venom gland transcriptome: analysis of gene expression profile.

  2009cites this paper
• Reptile Toxinology, Systematics, and Venom Gland Structure

  2009cites this paper
• Transcriptoma da glândula de peçonha de Crotalus durissus collilineatus: análise do perfil de expressão gênica

  2008cites this paper
• [Snake venoms C-type lectins and their receptors on platelets and cancerous cells].

  2008cites this paper
• Venom Composition in Rattlesnakes: Trends and Biological Significance

  2008cites this paper
• Effect of multimer size and a natural dimorphism on the binding of convulxin to platelet glycoprotein (GP)VI

  2006cites this paper
• FACTOR X ACTIVATING PROTEASES FROM SNAKE VENOMS

  2006cites this paper
• Molecular and sugar-binding heterogeneity of C-type lectins from Osmerus (Spirinchus) lanceolatus eggs.

  2005cites this paper
• Structures and functions of snake venom CLPs (C-type lectin-like proteins) with anticoagulant-, procoagulant-, and platelet-modulating activities.

  2005cites this paper
• Snake venom C-type lectins interacting with platelet receptors. Structure-function relationships and effects on haemostasis.

  2005cites this paper
• Molecular diversity and accelerated evolution of C-type lectin-like proteins from snake venom.

  2005cites this paper
• Structure of the snake-venom toxin convulxin.

  2004cites this paper
• Purpureotin: a novel di-dimeric C-type lectin-like protein from Trimeresurus purpureomaculatus venom is stabilized by noncovalent interactions.

  2004cites this paper
• Cloning, expression, and structural analysis of recombinant BJcuL, a c-type lectin from the Bothrops jararacussu snake venom.

  2004cites this paper
• Factor X activator from Vipera lebetina venom is synthesized from different genes.

  2004cites this paper
• Stejnulxin, a novel snake C-type lectin-like protein from Trimeresurus stejnegeri venom is a potent platelet agonist acting specifically via GPVI

  2003influential citation
• Novel sequences encoding venom C-type lectins are conserved in phylogenetically and geographically distinct Echis and Bitis viper species.

  2003cites this paper
• Convulxin Binds to Native, Human Glycoprotein Ibα*

  2003cites this paper
• A tetrameric glycoprotein Ib-binding protein, agglucetin, from Formosan pit viper: structure and interaction with human platelets

  2003cites this paper
• Initial structural analysis of an α4β4 C-type lectin from the venom of Crotalus durissus terrificus

  2003cites this paper
• Evolutionary analysis reveals collective properties and specificity in the C‐type lectin and lectin‐like domain superfamily

  2003cites this paper
• Crystal structure of the platelet activator convulxin, a disulfide-linked α4β4 cyclic tetramer from the venom of Crotalus durissus terrificus

  2003cites this paper
• Initial structural analysis of an alpha4beta4 C-type lectin from the venom of Crotalus durissus terrificus.

  2003cites this paper
• Lebecetin, a potent antiplatelet C-type lectin from Macrovipera lebetina venom.

  2003cites this paper
• Crystal structure of the platelet activator convulxin, a disulfide-linked alpha4beta4 cyclic tetramer from the venom of Crotalus durissus terrificus.

  2003cites this paper
• Calcium‐binding analysis and molecular modeling reveal echis coagulation factor IX/factor X‐binding protein has the Ca‐binding properties and Ca ion‐independent folding of other C‐type lectin‐like proteins

  2002cites this paper
• Alboluxin, a Snake C-type Lectin from Trimeresurus albolabris Venom is a Potent Platelet Agonist acting via GPIb and GPVI

  2002cites this paper
• Purification and cloning of a novel C-type lectin-like protein with platelet aggregation activity from Trimeresurus mucrosquamatus venom.

  2002cites this paper
• Lipid Rafts Orchestrate Signaling by the Platelet Receptor Glycoprotein VI*

  2002cites this paper
• Purification, crystallization and preliminary X-ray crystallographic analysis of agkaggregin, a C-type lectin-like protein from Agkistrodon acutus venom.

  2002cites this paper
• Determination of Crotalus durissus cascavella venom components that induce renal toxicity in isolated rat kidneys.

  2002cites this paper
• Animal lectins: a historical introduction and overview.

  2002cites this paper
• Expression and functional characterisation of the collagen receptor glycoprotein VI

  2001cites this paper
• A Novel Viper Venom Metalloproteinase, Alborhagin, Is an Agonist at the Platelet Collagen Receptor GPVI*

  2001cites this paper
• Bilinexin, a Snake C-type Lectin from Agkistrodon bilineatus Venom Agglutinates Platelets via GPIb and α2β1

  2001cites this paper
• A novel dimer of a C‐type lectin‐like heterodimer from the venom of Calloselasma rhodostoma (Malayan pit viper)

  2001cites this paper
• The Use of Snake Venom Toxins as Tools to Study Platelet Receptors for Collagen and von Willebrand Factor

  2001cites this paper
• Convulxin binding to platelet receptor GPVI: competition with collagen related peptides.

  2000cites this paper
• Expression of the collagen receptor glycoprotein VI during megakaryocyte differentiation.

  2000cites this paper
• Purification and cDNA cloning of salmorin that inhibits fibrinogen clotting.

  2000cites this paper
• Crystal structure of flavocetin-A, a platelet glycoprotein Ib-binding protein, reveals a novel cyclic tetramer of C-type lectin-like heterodimers.

  2000cites this paper
• What can venom phospholipases A(2) tell us about the functional diversity of mammalian secreted phospholipases A(2)?

  2000cites this paper
• Isolation and characterization of EMS16, a C-lectin type protein from Echis multisquamatus venom, a potent and selective inhibitor of the alpha2beta1 integrin.

  2000cites this paper
• Glycoprotein Ib-binding Protein from the Venom of Deinagkistrodon acutus – cDNA Sequence, Functional Characterization, and Three-Dimensional Modeling

  2000cites this paper
• Molecular cloning of glycoprotein Ib-binding protein, flavocetin-A, which inhibits platelet aggregation.

  2000cites this paper
• Role of the recombinant non-integrin platelet collagen receptor P65 on platelet activation induced by convulxin.

  2000cites this paper
• Identification of bothrojaracin-like proteins in snake venoms from Bothrops species and Lachesis muta.

  1999cites this paper
• Phosphatidylinositol 3′‐kinase and tyrosine‐phosphatase activation positively modulate Convulxin‐induced platelet activation. Comparison with collagen

  1999cites this paper
• Cloning of a galactose-binding lectin from the venom of Trimeresurus stejnegeri.

  1999cites this paper
• Crystallization and preliminary x-ray studies of flavocetin-A, a platelet glycoprotein Ib-binding protein from the habu snake venom.

  1999cites this paper
• Molecular cloning and sequence analysis of aggretin, a collagen-like platelet aggregation inducer.

  1999cites this paper
• The p85 Subunit of Phosphatidylinositol 3-Kinase Associates with the Fc Receptor γ-Chain and Linker for Activitor of T Cells (LAT) in Platelets Stimulated by Collagen and Convulxin*

  1998cites this paper