Carotid blowout syndrome in patients treated by larynx cancer

Introduction Carotid blowout syndrome is an uncommon complication for patient treated by head and neck tumors, and related to a high mortality rate. Objective The aim of this study was to study the risk of carotid blowout in a large cohort of patients treated only by larynx cancer. Methods Retrospective analysis of patients older than 18 years, treated by larynx cancer who developed a carotid blowout syndrome in a tertiary academic centre. Results 197 patients met the inclusion criteria, 192 (98.4%) were male and 5 (1.6%) were female. 6 (3%) patients developed a carotid blowout syndrome, 4 patients had a carotid blowout syndrome located in the internal carotid artery and 2 in the common carotid artery. According to the type of rupture, 3 patients suffer a type I, 2 patients a type III and 1 patient a type II. Five of those patients had previously undergone radiotherapy and all patients underwent total laryngectomy. We found a statistical correlation between open surgical procedures (p = 0.004) and radiotherapy (p = 0.023) and the development of a carotid blowout syndrome. Conclusion Carotid blowout syndrome is an uncommon complication in patients treated by larynx tumours. According to our results, patient underwent radiotherapy and patients treated with open surgical procedures with pharyngeal opening have a major risk to develop this kind of complication.

• Publication year

  2016

• Venue

  Brazilian Journal of Otorhinolaryngology

• Publication date

  2016-09-29

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.bjorl.2016.08.013PMID 27789194PMCID 9449226
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Carotid blowout in patients with head and neck cancer: Associated factors and treatment outcomes

  2015influential reference
• Serum albumin is an important prognostic factor for carotid blowout syndrome.

  2013cited by this paper
• Risk of carotid blowout after reirradiation of the head and neck: a systematic review.

  2012cited by this paper
• Salvage surgery after radiotherapy for oropharyngeal cancer. Treatment complications and oncological results.

  2011cited by this paper
• Acute Life-Threatening Hemorrhage in Patients with Head and Neck Cancer Presenting with Carotid Blowout Syndrome: Follow-Up Results after Initial Hemostasis with Covered-Stent Placement

  2011cited by this paper
• Carotid Blowout in Patients with Head and Neck Cancer

  2010influential reference
• Patients with head and neck cancers and associated postirradiated carotid blowout syndrome: endovascular therapeutic methods and outcomes.

  2008cited by this paper
• Endovascular management of carotid blowout syndrome in patients with head and neck cancers.

  2008cited by this paper
• Phase I trial of tirapazamine, cisplatin, and concurrent accelerated boost reirradiation in patients with recurrent head and neck cancer.

  2007cited by this paper
• Placement of Covered Stents for Carotid Blowout in Patients with Head and Neck Cancer: Follow-up Results after Rescue Treatments

  2007cited by this paper
• The management of carotid artery rupture

  2005influential reference
• Preliminary experience with endovascular reconstruction for the management of carotid blowout syndrome.

  2003cited by this paper
• Recurrent carotid blowout syndrome: diagnostic and therapeutic challenges in a newly recognized subgroup of patients.

  1999cited by this paper
• Endovascular therapy for the carotid blowout syndrome in head and neck surgical patients: diagnostic and managerial considerations.

  1996cited by this paper
• Management of carotid artery rupture by monitored endovascular therapeutic occlusion (1988‐1994)

  1995cited by this paper
• Radical neck dissection: a 19-year experience

  1989cited by this paper
• Transarterial carotid occlusion. Case report and review of the literature.

  1984cited by this paper
• Transarterial carotid occlusion. Case report and review of the literature.

  1984cited by this paper
• Radiation-induced arterial injuries.

  1983influential reference
• Carotid arterial hemorrhage after radical head and neck surgery.

  1979cited by this paper
• Carotid artery rupture

  1973cited by this paper
• Clinicopathologic study of the resected carotid artery. Analysis of sixty-four cases.

  1973cited by this paper
• Clinicopathologic study of the resected carotid artery

  1973cited by this paper
• Factors influencing the safety of carotid ligation.

  1969cited by this paper
• Rupture of the carotids following radical neck surgery in radiated patients.

  1962cited by this paper
• Rupture of the carotids following radical neck surgery in radiated patients.

  1962cited by this paper

• Endovascular treatment of acute carotid blowout syndrome - a case report

  2025cites this paper
• Emergency Management and Nursing Considerations of Carotid Blowout Syndrome.

  2024cites this paper
• Edge De-epithelialization for Reducing Pharyngocutaneous Fistula in Patch Free Flap Reconstructions for Salvage Total Laryngectomy Defects: A Case-Control Study

  2024cites this paper
• Intraglandular botulinum toxin in postoperative head and neck fistula: a retrospective analysis

  2024cites this paper
• Concurrent chemoradiotherapy using gemcitabine and nedaplatin in recurrent or locally advanced head and neck squamous cell carcinoma

  2022cites this paper
• Carotid arterial blowout after organ preserving chemoradiation therapy in hypopharyngeal cancer

  2022cites this paper
• Carotid Blowout Syndrome in Head and Neck Cancer Patients: Management of Patients At Risk for CBS

  2022cites this paper
• Carotid Blowout Syndrome in the Emergency Department: A Case Report and Review of the Literature.

  2022cites this paper
• Cyberknife Radiosurgery for the Treatment of Head and Neck Cancer: A Systematic Review

  2021cites this paper
• Management of postreconstructive head and neck salivary fistulae: A review of current practices.

  2021cites this paper
• Risk factors and Nomogram for Predicting Carotid Blowout Syndrome Based on Computed Tomography Angiography.

  2021cites this paper
• Prevention and early management of carotid blowout syndrome for patients receiving head and neck salvage boron neutron capture therapy (BNCT)

  2021cites this paper
• Vascular Complications

  2021cites this paper
• Carotid blowout management in the endovascular era.

  2020cites this paper
• Rupture of carotid artery pseudoaneurysm in the modern era of definitive chemoradiation for head and neck cancer: Two case reports

  2020cites this paper
• Surveillance

  2019cites this paper
• Early mortality after diagnosis of cancer of the head and neck – A population-based nationwide study

  2019cites this paper
• Endovascular management of the carotid blowout syndrome: a single-center experience

  2019cites this paper
• Viabahn stent extrusion into the airway in association with nasopharyngeal squamous cell carcinoma

  2019cites this paper
• Outcome of carotid and subclavian blowout syndrome in patients with pharynx- and larynx carcinoma passing a standardized multidisciplinary treatment

  2018influential citation