Amino Acid Biosynthesis in the Spirochete Leptospira: Evidence for a Novel Pathway of Isoleucine Biosynthesis

No abstract is available for this paper.

• Publication year

  1974

• Venue

  Journal of Bacteriology

• Publication date

  1974-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/jb.117.1.203-211.1974PMID 4808901PMCID PMC246544
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Alternate Pathway for Isoleucine Biosynthesis in Escherichia coli

  1972cited by this paper
• Enzymatic isomerization of -methylmate to (-)citramalate by a soil bacterium.

  1971cited by this paper
• Metabolism of -methylmalic acid by a soil bacterium.

  1971cited by this paper
• β-Oxidation of fatty acids by Leptospira

  1970cited by this paper
• Lipids of Parasitic and Saprophytic Leptospires

  1970cited by this paper
• Serogroups and serotypes in Water-Leptospira strains.

  1970cited by this paper
• Beta-oxidation of fatty acids by Leptospira.

  1970cited by this paper
• Alpha-isopropylmalate synthase from Salmonella typhimurium. Purification and properties.

  1969cited by this paper
• Intermediate Energy Metabolism of Leptospira

  1969cited by this paper
• Isoleucine Biosynthesis from 2-Methylbutyric Acid by Anaerobic Bacteria from the Rumen

  1969cited by this paper
• Studies on the metabolism of fatty acids in Leptospira: the biosynthesis of delta 9- and delta 11-monounsaturated acids.

  1969cited by this paper
• Regulation of Branched-Chain Amino Acid Biosynthesis in Salmonella typhimurium: Isolation of Regulatory Mutants

  1969cited by this paper
• Characterization of leptospires according to fatty acid requirements.

  1969cited by this paper
• α-Isopropylmalate Synthase from Salmonella typhimurium PURIFICATION AND PROPERTIES

  1969cited by this paper
• Studies on the Metabolism of Fatty Acids in Leptospira: The Biosynthesis of Δ9‐ and Δ11‐Monounsaturated Acids

  1969cited by this paper
• Metabolism of ethylmalic acids by Pseudomonas aeruginosa.

  1968cited by this paper
• Scintillation counting of the ninhydrin-amino acid-C14 reaction products from an automatic amino acid analyzer.

  1968cited by this paper
• STUDIES ON (-)-CITRAMALIC ACID FORMATION BY RESPIRATION-DEFICIENT YEAST MUTANTS

  1967cited by this paper
• Current problems in leptospirosis research. Report of a WHO Expert Group.

  1967cited by this paper
• Leptospirosis. I.

  1967cited by this paper
• Differentiation of Pathogenic and Saprophytic Leptospires I. Growth at Low Temperatures

  1967cited by this paper
• THE FORMATION OF ISOLEUCINE FROM BETA-METHYLASPARTIC ACID IN ESCHERICHIA COLI W.

  1965cited by this paper
• ACCELERATED AUTOMATIC CHROMATOGRAPHIC ANALYSIS OF AMINO ACIDS ON A SPHERICAL RESIN.

  1965cited by this paper
• The α-Isopropylmalate Synthetase of Neurospora. I. The Kinetics and End Product Control of α-Isopropylmalate Synthetase Function*

  1965cited by this paper
• METABOLISM OF LEPTOSPIRAE. I. UTILIZATION OF AMINO ACIDS AND PURINE, AND PYRIMIDINE BASES.

  1964cited by this paper
• THE GLUTAMATE MUTASE SYSTEM. ASSAYS AND PROPERTIES.

  1964cited by this paper
• NUTRITION OF LEPTOSPIRA POMONA. II. FATTY ACID REQUIREMENTS.

  1963cited by this paper
• Continuous scintillation counting of carbon-14 and tritium in effluent of the automatic amino acid analyzer.

  1962cited by this paper
• Feedback control by endproduct inhibition.

  1961cited by this paper
• The pathway of formation of n-butyl and n-amyl alcohols by a mutant strain of Saccharomyces cerevisiae

  1961cited by this paper
• The formation of n-propyl alcohol by Saccharomyces cerevisiae.

  1961cited by this paper
• A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter

  1960cited by this paper
• The metabolic significance of the citric acid cycle in the growth of the fungus Zygorrhynchus moelleri.

  1957cited by this paper
• Studies of biosynthesis in escherichia coli

  1955cited by this paper

• Gut microbiota-driven BCAA biosynthesis via Staphylococcus aureus -expressed acetolactate synthase impairs glycemic control in type 2 diabetes in South China.

  2025cites this paper
• Heterotrophic and autotrophic production of L-isoleucine and L-valine by engineered Cupriavidus necator H16.

  2024cites this paper
• Bridging the gap between maleate hydratase, citraconase and isopropylmalate isomerase: Insights into the single broad-specific enzyme.

  2022cites this paper
• Carbon utilization phenome of Leptospira interrogans serovar Manilae strain K64

  2021cites this paper
• Underground isoleucine biosynthesis pathways in E. coli

  2020cites this paper
• Thermodynamic favorability and pathway yield as evolutionary tradeoffs in biosynthetic pathway choice

  2018cites this paper
• The Origin and Nature of Life on Earth: The Emergence of the Fourth Geosphere

  2016cites this paper
• Human gut microbes impact host serum metabolome and insulin sensitivity

  2016cites this paper
• Mesaconase/Fumarase FumD in Escherichia coli O157:H7 and Promiscuity of Escherichia coli Class I Fumarases FumA and FumB

  2015cites this paper
• The Family Leptospiraceae

  2014cites this paper
• Metabolic Evolution of a Deep-Branching Hyperthermophilic Chemoautotrophic Bacterium

  2013cites this paper
• Chemotactic Behavior of Pathogenic and Nonpathogenic Leptospira Species

  2012cites this paper
• Stable Isotope Peptide Mass Spectrometry To Decipher Amino Acid Metabolism in Dehalococcoides Strain CBDB1

  2012cites this paper
• Stable isotope peptide mass spectrometry to decipher amino 1 acid metabolism in Dehalococcoides strain CBDB 1 2 3

  2012cites this paper
• DIAGNÓSTICO SOROLÓGICO DA LEPTOSPIROSE: BENEFÍCIO DE AMOSTRA AGUDA TARDIA NA CONFIRMAÇÃO DE CASOS

  2011cites this paper
• Alternative isoleucine synthesis pathway in cyanobacterial species.

  2010cites this paper
• Expanding metabolism for total biosynthesis of the nonnatural amino acid L-homoalanine

  2010cites this paper
• Phylum XV. Spirochaetes Garrity and Holt 2001

  2010cites this paper
• Molecular basis of the inhibitor selectivity and insights into the feedback inhibition mechanism of citramalate synthase from Leptospira interrogans.

  2009cites this paper
• Engineering metabolic systems for production of advanced fuels

  2009cites this paper
• Coenzyme B, amino acid, and iron-sulfur cluster biosynthesis in methanogenic archaea

  2009cites this paper
• Cohesion Group Approach for Evolutionary Analysis of Aspartokinase, an Enzyme That Feeds a Branched Network of Many Biochemical Pathways

  2009cites this paper
• Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels

  2008cites this paper
• Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans.

  2008cites this paper
• Insights into the Autotrophic CO2 Fixation Pathway of the Archaeon Ignicoccus hospitalis: Comprehensive Analysis of the Central Carbon Metabolism

  2007cites this paper
• A comprehensive survey on isoleucine biosynthesis pathways in seven epidemic Leptospira interrogans reference strains of China.

  2007cites this paper
• Enzymology and Evolution of the Pyruvate Pathway to 2-Oxobutyrate in Methanocaldococcus jannaschii

  2007cites this paper
• Medio EMJH modificado para el cultivo de Leptospira interrogans serogrupo Ballum

  2006cites this paper
• Isolation and Characterization of FecA- and FeoB-Mediated Iron Acquisition Systems of the Spirochete Leptospira biflexa by Random Insertional Mutagenesis

  2005cites this paper
• Isoleucine Biosynthesis in Leptospira interrogans Serotype lai Strain 56601 Proceeds via a Threonine-Independent Pathway

  2004influential citation
• Leptospira spp. possess a complete haem biosynthetic pathway and are able to use exogenous haem sources

  2003cites this paper
• Determined by 13C Nuclear Magnetic Resonancet

  2003cites this paper
• Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri.

  2003cites this paper
• Elucidation of methanogenic coenzyme biosyntheses: from spectroscopy to genomics.

  2002cites this paper
• Bioreaction network topology and metabolic flux ratio analysis by biosynthetic fractional 13C labeling and two-dimensional NMR spectroscopy.

  1999cites this paper
• ( R )-Citramalate Synthase in Methanogenic Archaea

  1999cites this paper
• Bioreaction Network Topology a by Biosynthetic Fracti Two-Dimensional N

  1999cites this paper
• Amino Acid Biosynthesis in the Halophilic ArchaeonHaloarcula hispanica

  1999cites this paper
• Homoserine O-Acetyltransferase , Involved in the Leptospira meyeri Methionine Biosynthetic Pathway , Is Not Feedback Inhibited

  1997cites this paper
• Homoserine O-acetyltransferase, involved in the Leptospira meyeri methionine biosynthetic pathway, is not feedback inhibited

  1997cites this paper
• The spirochaetes: A different way of life

  1995cites this paper
• Cloning and analysis of the leuB gene of Leptospira interrogans serovar pomona.

  1993cites this paper
• Comparison of genetic maps for two Leptospira interrogans serovars provides evidence for two chromosomes and intraspecies heterogeneity

  1993cites this paper
• Enzymes of a novel autotrophic CO2 fixation pathway in the phototrophic bacterium Chloroflexus aurantiacus, the 3-hydroxypropionate cycle.

  1993cites this paper
• Groundworks for an evolutionary biochemistry: the iron-sulphur world.

  1992cites this paper
• Cloning of dapD, aroD and asd of Leptospira interrogans serovar icterohaemorrhagiae, and nucleotide sequence of the asd gene.

  1992cites this paper
• The Genus Leptospira

  1992cites this paper
• Cloning of genes required for amino acid biosynthesis from Leptospira interrogans serovar icterohaemorrhagiae.

  1990cites this paper
• Nucleotide sequence analysis of the Leptospira biflexa serovar patoc rpsL and rpsG genes

  1990cites this paper
• Organic nitrogen metabolism of phototrophic bacteria

  1989cites this paper
• A novel biosynthesis of medium chain length alpha-ketodicarboxylic acids in methanogenic archaebacteria.

  1989cites this paper
• 13C-NMR study of acetate assimilation in Thermoproteus neutrophilus.

  1989cites this paper
• Sensitivity of pathogenic and free-living Leptospira spp. to UV radiation and mitomycin C

  1988cites this paper
• Nucleotide sequence analysis of a gene cloned from Leptospira biflexa serovar patoc which complements an argE defect in Escherichia coli

  1988cites this paper
• Growth of Paracoccus denitrificanson [2, 3-13C]succinate and [1, 4-13C]succinate - II. Isoleucine biosynthesis

  1987cites this paper
• Physiological roles of two enzymes with fumarase activity in two Pseudomonads.

  1987cites this paper
• Carbon assimilation by the autotrophic thermophilic archaebacterium Thermoproteus neutrophilus

  1986cites this paper
• Analysis of cloned DNA from Leptospira biflexa serovar patoc which complements a deletion of the Escherichia coli trpE gene

  1986cites this paper
• Biosynthesis of isoleucine in methanogenic bacteria: a carbon-13 NMR study

  1984cites this paper
• Cloning of a gene required for tryptophan biosynthesis from Leptospira biflexa serovar patoc into Escherichia coli.

  1984cites this paper
• Isoleucine synthesis by Clostridium sporogenes from propionate or alpha-methylbutyrate.

  1984cites this paper
• Biosynthetic pathways in Methanospirillum hungatei as determined by 13C nuclear magnetic resonance

  1983cites this paper
• Multiple pathways for isoleucine biosynthesis in the spirochete Leptospira

  1983cites this paper
• Unusual pathway of isoleucine biosynthesis in Methanobacterium thermoautotrophicum

  1983cites this paper
• Diversity in the routing and regulation of complex biochemical pathways as indicators of microbial relatedness.

  1982cites this paper
• Axial filament involvement in the motility of Leptospira interrogans

  1979cites this paper
• Helix handedness of Leptospira interrogans as determined by scanning electron microscopy

  1979cites this paper
• Plate Assay for Detection of Leptospira interrogans serovar pomona Hemolysin

  1979cites this paper
• Amino acid biosynthesis and its regulation.

  1978cites this paper
• Physiology and evolution of spirochetes

  1977cites this paper
• Pathway for isoleucine formation form pyruvate by leucine biosynthetic enzymes in leucine-accumulating isoleucine revertants of Serratia marcescens.

  1977cites this paper
• Physiology and evolution of spirochetes.

  1977cites this paper
• Metabolism of threo-beta-methylmalate by a soil bacterium.

  1976cites this paper
• Relationship of metabolite inhibition of growth to flow-of-carbon patterns in nature.

  1976cites this paper
• COMPARATIVE SPIROCHETE PHYSIOLOGY AND CELLULAR COMPOSITION

  1976cites this paper
• Quantitative decarboxylation of (14C) amino acids using automatic amino acid analyzer.

  1976cites this paper
• Enzyme recruitment in evolution of new function.

  1976cites this paper
• Formation of beta-methylmalate and its conversion to citramalate in Rhodospirillum rubrum.

  1975cites this paper
• The ancient origin of a second microbial pathway for L-tyrosine biosynthesis in prokaryotes

  1975cites this paper
• Isoleucine Synthesis by Clostridium sporogenes from Propionate or aMe t h ylbu tyra

  year unknowncites this paper