Synergy between suppressor of Hairless and Notch in regulation of Enhancer of split m gamma and m delta expression

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Molecular and Cellular Biology

• Publication date

  1997-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.17.9.5620PMID 9271437PMCID PMC232410
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Conservation of the Notch signalling pathway in mammalian neurogenesis.

  1997cited by this paper
• Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element.

  1996cited by this paper
• Functional relationships between Notch, Su(H) and the bHLH genes of the E(spl) complex: the E(spl) genes mediate only a subset of Notch activities during imaginal development.

  1996cited by this paper
• Subcellular localization of Suppressor of Hairless in Drosophila sense organ cells during Notch signalling.

  1996influential reference
• Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

  1996influential reference
• The shortest path from the surface to the nucleus: RBP‐Jκ/Su(H) transcription factor

  1996cited by this paper
• The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands.

  1996cited by this paper
• lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H).

  1996cited by this paper
• Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

  1996cited by this paper
• A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis.

  1996cited by this paper
• Alterations in Notch signaling in neoplastic lesions of the human cervix.

  1995cited by this paper
• Neurogenic and proneural genes control cell fate specification in the Drosophila endoderm.

  1995cited by this paper
• Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

  1995cited by this paper
• Jagged: a mammalian ligand that activates Notch1.

  1995cited by this paper
• Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats.

  1995cited by this paper
• Role of Notch and achaete-scute complex in the expression of Enhancer of split bHLH proteins

  1995cited by this paper
• Notch signaling.

  1995cited by this paper
• Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-J kappa/Su(H).

  1995cited by this paper
• Signalling downstream of activated mammalian Notch

  1995cited by this paper
• Serrate signals through Notch to establish a Wingless-dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing.

  1995cited by this paper
• Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)

  1995cited by this paper
• The neurogenic suppressor of hairless DNA-binding protein mediates the transcriptional activation of the enhancer of split complex genes triggered by Notch signaling.

  1995influential reference
• Suppressor of hairless directly activates transcription of enhancer of split complex genes in response to Notch receptor activity.

  1995influential reference
• Antagonistic activities of Suppressor of Hairless and Hairless control alternative cell fates in the Drosophila adult epidermis.

  1994cited by this paper
• The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.

  1994cited by this paper
• The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo.

  1994cited by this paper
• Inhibition of the DNA-binding activity of Drosophila suppressor of hairless and of its human homolog, KBF2/RBP-J kappa, by direct protein-protein interaction with Drosophila hairless.

  1994cited by this paper
• The suppressor of hairless protein participates in notch receptor signaling.

  1994cited by this paper
• Roles of the Notch gene in Drosophila wing morphogenesis.

  1994influential reference
• Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor.

  1993influential reference
• Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei.

  1993cited by this paper
• An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye

  1993influential reference
• The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.

  1992cited by this paper
• The involvement of the Notch locus in Drosophila oogenesis.

  1992cited by this paper
• Signalling by the sevenless protein tyrosine kinase is mimicked by Rasl activation

  1992cited by this paper
• Human homologs of a Drosophila Enhancer of Split gene product define a novel family of nuclear proteins

  1992cited by this paper
• Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins.

  1992cited by this paper
• A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells.

  1991cited by this paper
• Transposon-facilitated DNA sequencing.

  1991cited by this paper
• Role of neurogenic genes in establishment of follicle cell fate and oocyte polarity during oogenesis in Drosophila.

  1991cited by this paper
• Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila.

  1990cited by this paper
• Notch is required for successive cell decisions in the developing Drosophila retina.

  1989cited by this paper
• The enhancer of split locus and neurogenesis in Drosophila melanogaster.

  1987cited by this paper
• Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors

  1986cited by this paper
• Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats.

  1985cited by this paper
• A comprehensive set of sequence analysis programs for the VAX

  1984cited by this paper
• On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

  1983cited by this paper
• Transformation of mammalian cells with genes from procaryotes and eucaryotes.

  1979cited by this paper

• Morphogen and juxtacrine signalling dynamically integrate to specify cell fates with single-cell resolution

  2025cites this paper
• The Binding of CSL Proteins to Either Co-Activators or Co-Repressors Protects from Proteasomal Degradation Induced by MAPK-Dependent Phosphorylation

  2022cites this paper
• Limited Availability of General Co-Repressors Uncovered in an Overexpression Context during Wing Venation in Drosophila melanogaster

  2020cites this paper
• The silent information regulator 1 (Sirt1) is a positive regulator of the Notch pathway in Drosophila.

  2016cites this paper
• Origin and evolution of the enhancer of split complex

  2015cites this paper
• Cloning and Expression Characteristics of the Notch-Associated Gene BmE(spl)mγ from Silkworm, Bombyx mori

  2014cites this paper
• Hamlet Notches fate

  2012cites this paper
• Main components of gene network controlling development of dorsal appendages of egg chorion in Drosophila melanogaster

  2012cites this paper
• Molecular Analysis of the Notch Repressor-Complex in Drosophila: Characterization of Potential Hairless Binding Sites on Suppressor of Hairless

  2011cites this paper
• Evolution of a genomic regulatory domain: the role of gene co-option and gene duplication in the Enhancer of split complex.

  2010cites this paper
• Differential expression of the Enhancer of split genes in the developing Drosophila midgut.

  2009cites this paper
• OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development

  2008cites this paper
• γ-Secretase Mediated Proteolysis: At the Cutting Edge of Notch Signaling

  2007cites this paper
• Phylogenetic Footprinting Analysis in the Upstream Regulatory Regions of the Drosophila Enhancer of split Genes

  2007influential citation
• Kaposi's Sarcoma-Associated Herpesvirus Lytic Switch Protein Stimulates DNA Binding of RBP-Jk/CSL To Activate the Notch Pathway

  2006cites this paper
• Regulation of E(spl) Gene Expression During Development

  2006cites this paper
• The Effect of Polymorphisms in the Enhancer of split Gene Complex on Bristle Number Variation in a Large Wild-Caught Cohort of Drosophila melanogaster

  2005cites this paper
• Identifying signatures of selection at the enhancer of split neurogenic gene complex in Drosophila.

  2005cites this paper
• The Enhancer of split and Achaete-Scute complexes of Drosophilids derived from simple ur-complexes preserved in mosquito and honeybee

  2005cites this paper
• Bre1 is required for Notch signaling and histone modification.

  2005cites this paper
• Bunched sets a boundary for Notch signaling to pattern anterior eggshell structures during Drosophila oogenesis.

  2005cites this paper
• Notch and VEGF Interactions in Breast Cancer

  2004cites this paper
• Genetic evidence that Notch affects independently the development of machrochaeta and wing venation in Drosophila melanogaster.

  2004cites this paper
• Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation.

  2004cites this paper
• Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes.

  2003cites this paper
• UNRAVELING THE FUNCTIONAL MOTIFS OF THE YAN ENHANCER IN DROSOPHILA MELANOGASTER

  2003cites this paper
• Notch Signaling in Primary Endothelial Cells

  2003cites this paper
• Deltex/Dtx mediates NOTCH signaling in regulation of Bmp4 expression in cranial neural crest formation during avian development

  2003cites this paper
• Drosophila nicastrin is essential for the intramembranous cleavage of notch.

  2002cites this paper
• SCORE: A computational approach to the identification of cis-regulatory modules and target genes in whole-genome sequence data

  2002cites this paper
• A Human Protein with Sequence Similarity to DrosophilaMastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters

  2001cites this paper
• Molecular diversity in the Notch receptor family

  2001cites this paper
• A model Notch response element detects Suppressor of Hairless-dependent molecular switch.

  2001cites this paper
• Groucho mediates a Ci-independent mechanism of hedgehog repression in the anterior wing pouch.

  2001cites this paper
• Spatially restricted factors cooperate with notch in the regulation of Enhancer of split genes.

  2000cites this paper
• Antagonism of notch signaling activity by members of a novel protein family encoded by the bearded and enhancer of split gene complexes.

  2000cites this paper
• Dissecting the mechanisms of suppressor of hairless function.

  2000cites this paper
• Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins.

  2000cites this paper
• A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE.

  2000cites this paper
• Notch signaling in the nervous system. Pieces still missing from the puzzle.

  2000cites this paper
• The Enhancer of split complex of Drosophila melanogaster harbors three classes of Notch responsive genes.

  1999cites this paper
• Overexpression of the m4 and mα genes of the E(spl)-Complex antagonizes Notch mediated lateral inhibition

  1999cites this paper
• Discrete enhancer elements mediate selective responsiveness of enhancer of split complex genes to common transcriptional activators.

  1999influential citation
• Frizzled regulation of Notch signalling polarizes cell fate in the  Drosophila eye

  1999cites this paper
• Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

  1999cites this paper
• SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans.

  1999cites this paper
• Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

  1999cites this paper
• Cell proliferation control by Notch signaling in Drosophila development.

  1998cites this paper
• A subset of notch functions during Drosophila eye development require Su(H) and the E(spl) gene complex.

  1998cites this paper
• LIN-12/Notch signaling: lessons from worms and flies.

  1998cites this paper
• Delta-1 Activation of Notch-1 Signaling Results inHES-1 Transactivation

  1998cites this paper
• Human deltex is a conserved regulator of Notch signalling

  1998cites this paper
• Notch signalling in Drosophila: three ways to use a pathway.

  1998cites this paper
• The mammalian transcriptional repressor RBP (CBF1) targets TFIID and TFIIA to prevent activated transcription.

  1998cites this paper
• Nuclear access and action of notch in vivo.

  1998cites this paper
• Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements.

  1997cites this paper