Lumican, a small leucine‐rich proteoglycan substituted with keratan sulfate chains is expressed and secreted by human melanoma cells and not normal melanocytes

No abstract is available for this paper.

• Publication year

  2006

• Venue

  IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology

• Publication date

  2006-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1080/15216540600951605PMID 17050378
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2005influential reference
• Influence of aging on glycosaminoglycans and small leucine-rich proteoglycans production by skin fibroblasts

  2005cited by this paper
• Pancreatic tumor cells influence the composition of the extracellular matrix.

  2004cited by this paper
• Lumican expression is associated with the formation of mesenchyme‐like elements in salivary pleomorphic adenomas

  2004cited by this paper
• The small leucine-rich proteoglycan lumican inhibits melanoma progression.

  2004cited by this paper
• Reduced expression of the small leucine-rich proteoglycans, lumican, and decorin is associated with poor outcome in node-negative invasive breast cancer.

  2003cited by this paper
• How does skin adapt to repetitive mechanical stress to become load tolerant?

  2003cited by this paper
• Age-related Changes in the Proteoglycans of Human Skin

  2003cited by this paper
• Expression and accumulation of lumican protein in uterine cervical cancer cells at the periphery of cancer nests.

  2002cited by this paper
• Glycosphingolipid‐dependent cross‐talk between glycosynapses interfacing tumor cells with their host cells: essential basis to define tumor malignancy

  2002cited by this paper
• Lumican expression in alpha cells of islets in pancreas and pancreatic cancer cells

  2002cited by this paper
• Expression of lumican in human colorectal cancer cells

  2002cited by this paper
• Focus on melanoma.

  2002cited by this paper
• Transcriptional activation of collagenase‐3 by transforming growth factor‐β1 is via MAPK and Smad pathways in human breast cancer cells

  2002cited by this paper
• Biological consequences of tumor hypoxia.

  2001cited by this paper
• Expression of lumican in human breast carcinoma.

  1998influential reference
• Macrophage receptors for lumican. A corneal keratan sulfate proteoglycan.

  1997cited by this paper
• The Human Lumican Gene

  1995cited by this paper
• Molecular polymorphism of lumican during corneal development.

  1994cited by this paper
• Histopathology of the skin

  1975cited by this paper

• The Landscape of Small Leucine-Rich Proteoglycan Impact on Cancer Pathogenesis with a Focus on Biglycan and Lumican

  2023cites this paper
• The expression of keratan sulfate in malignant melanoma enhances the adhesion and invasion activity of melanoma cells

  2022cites this paper
• Lumican inhibits immune escape and carcinogenic pathways in colorectal adenocarcinoma

  2021cites this paper
• Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease

  2020cites this paper
• Keratan Sulphate in the Tumour Environment.

  2020cites this paper
• The Tumor Microenvironment: Focus on Extracellular Matrix.

  2020cites this paper
• Small Leucine-Rich Proteoglycans in Skin Wound Healing

  2020cites this paper
• Epithelial-to-Mesenchymal Transition and invadopodia markers in breast cancer: Lumican a key regulator.

  2020cites this paper
• Role of keratan sulfate expression in human pancreatic cancer malignancy

  2019cites this paper
• Proteoglycans remodeling in cancer: Underlying molecular mechanisms.

  2017cites this paper
• Lumican delays melanoma growth in mice and drives tumor molecular assembly as well as response to matrix-targeted TAX2 therapeutic peptide

  2017cites this paper
• Extracellular matrix structure.

  2016cites this paper
• Lumican Inhibits SNAIL-Induced Melanoma Cell Migration Specifically by Blocking MMP-14 Activity

  2016cites this paper
• Variations in the expression of TIMP1, TIMP2 and TIMP3 in cutaneous melanoma with regression and their possible function as prognostic predictors

  2016cites this paper
• Proteoglycan form and function: A comprehensive nomenclature of proteoglycans

  2015cites this paper
• Proteoglycans in Normal and Healing Skin

  2015cites this paper
• Pathogenetic studies of sarcoma development in retriever breeds

  2014cites this paper
• Lumican affects tumor cell functions, tumor-ECM interactions, angiogenesis and inflammatory response.

  2014cites this paper
• Computational Approaches To Predict Phenotype Differences In Populations From High-throughput Sequencing Data

  2014cites this paper
• Roles of the small leucine-rich repeat proteoglycans OMD and PRELP in development and cancer

  2014cites this paper
• Lumican effects in the control of tumour progression and their links with metalloproteinases and integrins

  2013cites this paper
• Lumican expression, localization and antitumor activity in prostate cancer.

  2013cites this paper
• Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells

  2013cites this paper
• Gene Expression Profiling of Histiocytic Sarcomas in a Canine Model: The Predisposed Flatcoated Retriever Dog

  2013cites this paper
• Overexpression of lumican affects the migration of human colon cancer cells through up-regulation of gelsolin and filamentous actin reorganization.

  2012cites this paper
• Secreted 70kDa lumican stimulates growth and inhibits invasion of human pancreatic cancer.

  2012cites this paper
• Lumican inhibits angiogenesis by interfering with α2β1 receptor activity and downregulating MMP-14 expression.

  2011cites this paper
• Proteoglycans in cancer biology, tumour microenvironment and angiogenesis

  2011cites this paper
• Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil)

  2011cites this paper
• Towards New Therapeutic Targets: Identification of Novel Tumor Markers in Chronic Lymphocytic Leukemia

  2010cites this paper
• Proteoglycans and Cancer

  2010cites this paper
• Extracellular Matrix Proteins:Implications for Angiogenesis

  2010cites this paper
• Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans

  2010cites this paper
• Impaired skin wound healing in lumican‐null mice

  2010cites this paper
• EXTRACELLULAR MATRIX PROTEINS: IMPLICATIONS FOR ANGIOGENESIS

  2010cites this paper
• The matricellular functions of small leucine-rich proteoglycans (SLRPs)

  2009cites this paper
• Lumican inhibits B16F1 melanoma cell lung metastasis.

  2009cites this paper
• GST‐P1 as a histological biomarker of synovial sarcoma revealed by proteomics

  2009cites this paper
• Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells

  2008cites this paper
• Lumican, a small leucine‐rich proteoglycan

  2008cites this paper
• Lumican affects actin cytoskeletal organization in human melanoma A375 cells.

  2008cites this paper
• Expression of lumican, a small leucine‐rich proteoglycan with antitumour activity, in human malignant melanoma

  2007cites this paper
• Role of lumican in cancer cells and adjacent stromal tissues in human pancreatic cancer.

  2007cites this paper