Significance of the bursa of fabricius after whole body x-irradiation.

Abstract THE bursa of Fabricius, during embryonic development and its early post-natal period, functions to confer antibody potential upon the chicken (Glick et al., 1956; Glick and Sadler, 1961; Mueller et al., 1962; Cooper et al., 1966). Removing the bursa after 5 weeks of age did not significantly affect antibody production (Chang et al., 1957). Although the bursa contains protein similar to immunoglobulin (Marinkovich and Baluda, 1966; Glick and Whatley, 1967; Thorbecke et al., 1968), it is not a primary site of antibody formation (Dent and Good, 1965; Glick and Whatley, 1967; Jancovic and Mitrovic, 1967). Thus, immunological function of the bursa might be completed during its most rapid phase of post hatching growth (Glick, 1964). This article presents data which indicates that an intact bursa appears to be essential for the rapid recovery of antibody potential after x-irradiation. A preliminary report has been published (Sato and Gotoh, 1965). MATERIALS AND…

• Publication year

  1969

• Venue

  Poultry Science

• Publication date

  1969-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3382/PS.0481195PMID 5824183
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The immune response of bursaless birds as influenced by antibiotics and age.

  1968cited by this paper
• Immune globulin production by the bursa of Fabricius of young chickens.

  1968cited by this paper
• The Immune Response of Bursaless Birds as Influenced by Antibiotics and Age∗ †

  1968cited by this paper
• Antibody-producing cells in the chicken, as observed by fluorescent antibody technique.

  1967cited by this paper
• The presence of immunoglobulin in the bursa of Fabricius.

  1967cited by this paper
• Restoration of gamma globulin production in agammaglobulinemic chickens.

  1966cited by this paper
• In vitro synthesis of gamma M-like globulin by various chick embryonic cells.

  1966cited by this paper
• Restoration of Gamma Globulin Production in Agammaglobulinemic Chickens

  1966cited by this paper
• Restoration of Antibody Producing Capacity in Bursectomized Chickens by Bursal Grafts in Millipore® Chambers.∗

  1965cited by this paper
• Bursa of Fabricius in Chickens: Possible Humoral Factor

  1965cited by this paper
• Absence of Antibody Production in the Bursa of Fabricius

  1965cited by this paper
• Thymus: Its Role in Lymphoid Recovery after Irradiation

  1963cited by this paper
• THE EFFECT OF BURSECTOMY AT DIFFERENT AGES ON PRECIPITIN AND NATURAL HEMAGGLUTININ PRODUCTION IN THE CHICKEN.

  1963cited by this paper
• Role of the Thymus in Recovery of the Immune Mechanism in the Irradiated Adult Mouse

  1963cited by this paper
• Further studies on the role of the bursa of Fabricius in antibody production.

  1962cited by this paper
• The Elimination of the Bursa of Fabricius and Reduction of Antibody Production in Birds from Eggs Dipped in Hormone Solutions

  1961cited by this paper
• Extracts from the Bursa of Fabricius—A Lympho-Epithelial Gland of the Chicken—Stimulate the Production of Antibodies in Bursectomized Chickens

  1960cited by this paper
• The Significance of the Bursa of Fabricius in Antibody Production in Chickens 1. Age of Chickens

  1957cited by this paper
• Experimental Modification of the Growth of the Bursa of Fabricius

  1957cited by this paper
• Effect of Total Body X-Ray Irradiation on the Blood of Female Single Comb White Leghorn Chickens

  1957cited by this paper
• Precipitin production in chickens. XIII. A quantitative study of the effect of simultaneous injection of two antigens.

  1956cited by this paper
• The Bursa of Fabricius and Antibody Production

  1956cited by this paper
• Further studies on the radiosensitive stages in hemolysin formation.

  1954cited by this paper
• Precipitin Production in Chickens

  1946cited by this paper

• Thymus dependency of antigen-binding cells in the bone marrow and spleen of chicks.

  1977cites this paper
• Humoral immunity of Japanese quail subjected to microwave radiation during embryogeny.

  1977cites this paper
• Radiation elicited changes in bursa of Fabricius and thymus during the ontogeny of chickens.

  1975cites this paper
• Production of mercaptoethanol sensitive antibody in bursectomized chicks.

  1972cites this paper