Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury

No abstract is available for this paper.

• Publication year

  2017

• Venue

  The FASEB Journal

• Publication date

  2017-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1096/fj.201700533RPMID 28729290PMCID PMC5636697
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Stromal Intervention: Regulation of Immunity and Inflammation at the Epithelial-Mesenchymal Barrier.

  2017cited by this paper
• IL-17–Producing Innate and Pathogen-Specific Tissue Resident Memory γδ T Cells Expand in the Lungs of Bordetella pertussis–Infected Mice

  2017cited by this paper
• Impaired Epidermal to Dendritic T Cell Signaling Slows Wound Repair in Aged Skin.

  2016cited by this paper
• Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome.

  2016cited by this paper
• CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis

  2016cited by this paper
• Selective accumulation of the complement membrane attack complex in aging choriocapillaris.

  2016cited by this paper
• The Role of Alpha-MSH as a Modulator of Ocular Immunobiology Exemplifies Mechanistic Differences between Melanocortins and Steroids

  2016cited by this paper
• Correction: CD73 Expressed on γδ T Cells Shapes Their Regulatory Effect in Experimental Autoimmune Uveitis

  2016cited by this paper
• Interleukin‐17A neutralization alleviated ocular neovascularization by promoting M2 and mitigating M1 macrophage polarization

  2016cited by this paper
• Connecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells

  2016cited by this paper
• Association of Choroidal Interleukin-17-Producing T Lymphocytes and Macrophages with Geographic Atrophy

  2016cited by this paper
• Responses of Multipotent Retinal Stem Cells to IL-1β, IL-18, or IL-17

  2015cited by this paper
• Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage.

  2015cited by this paper
• TRRUST: a reference database of human transcriptional regulatory interactions

  2015cited by this paper
• IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2+Vγ6+γδ T cells

  2015cited by this paper
• Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

  2015cited by this paper
• Retinal Cell Death Caused by Sodium Iodate Involves Multiple Caspase-Dependent and Caspase-Independent Cell-Death Pathways

  2015cited by this paper
• γδ T cells: first line of defense and beyond.

  2014cited by this paper
• Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation.

  2014cited by this paper
• γδ T cells as a major source of IL-17 production during age-dependent RPE degeneration.

  2014cited by this paper
• Subcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium.

  2014cited by this paper
• Aryl hydrocarbon receptor knock-out exacerbates choroidal neovascularization via multiple pathogenic pathways

  2014cited by this paper
• Deletion of aryl hydrocarbon receptor AHR in mice leads to subretinal accumulation of microglia and RPE atrophy.

  2014cited by this paper
• Sodium iodate induced retinal degeneration: new insights from an old model

  2014cited by this paper
• Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology

  2013cited by this paper
• Regulation of T-lymphocyte CCL3 and CCL4 production by retinal pigment epithelial cells.

  2013cited by this paper
• NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.

  2013cited by this paper
• IL-23 Receptor Expression on γδ T Cells Correlates with Their Enhancing or Suppressive Effects on Autoreactive T Cells in Experimental Autoimmune Uveitis

  2013cited by this paper
• IL-23–Independent Induction of IL-17 from γδT Cells and Innate Lymphoid Cells Promotes Experimental Intraocular Neovascularization

  2013cited by this paper
• Fgf9 from dermal γδ T cells induces hair follicle neogenesis after wounding

  2013cited by this paper
• Immunology of age-related macular degeneration

  2013cited by this paper
• The aryl hydrocarbon receptor in innate T cell immunity

  2013cited by this paper
• Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

  2013cited by this paper
• Immunosuppressive properties of regulatory T cells generated by incubation of peripheral blood mononuclear cells with supernatants of human RPE cells.

  2012cited by this paper
• Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave.

  2012cited by this paper
• The Living Eye “Disarms” Uncommitted Autoreactive T Cells by Converting Them to Foxp3+ Regulatory Cells following Local Antigen Recognition

  2012cited by this paper
• NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components

  2012cited by this paper
• Retinoic acid from retinal pigment epithelium induces T regulatory cells.

  2012cited by this paper
• The Rd8 mutation of the Crb1 gene is present in vendor lines of C57BL/6N mice and embryonic stem cells, and confounds ocular induced mutant phenotypes.

  2012cited by this paper
• Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD).

  2012cited by this paper
• Choriocapillaris vascular dropout related to density of drusen in human eyes with early age-related macular degeneration.

  2011cited by this paper
• The light and dark sides of intestinal intraepithelial lymphocytes

  2011cited by this paper
• Activated gammadelta T cells promote the activation of uveitogenic T cells and exacerbate EAU development.

  2011cited by this paper
• Cutaneous immunosurveillance by self-renewing dermal γδ T cells

  2011cited by this paper
• Circulating Reactive Oxidant Causes Apoptosis of Retinal Pigment Epithelium and Cone Photoreceptors in the Mouse Central Retina

  2011cited by this paper
• Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation.

  2011cited by this paper
• In Situ Dividing and Phagocytosing Retinal Microglia Express Nestin, Vimentin, and NG2 In Vivo

  2011cited by this paper
• Immune regulation in the retina

  2010cited by this paper
• Protein-Protein Interaction Network Evaluation for Identifying Potential Drug Targets

  2010cited by this paper
• gammadelta T cell subsets: a link between TCR and function?

  2010cited by this paper
• The Role of Indoleamine 2,3-Dioxygenase in Retinal Pigment Epithelial Cell-mediated Immune Modulation

  2010cited by this paper
• CCR6 and NK1.1 distinguish between IL‐17A and IFN‐γ‐producing γδ effector T cells

  2009cited by this paper
• Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

  2009cited by this paper
• A dominant, coordinated T regulatory cell-IgA response to the intestinal microbiota

  2009cited by this paper
• Relationship between RPE and choriocapillaris in age-related macular degeneration.

  2009cited by this paper
• Interleukin-10 Promotes Pathological Angiogenesis by Regulating Macrophage Response to Hypoxia during Development

  2008cited by this paper
• Direct labeling and visualization of blood vessels with lipophilic carbocyanine dye DiI

  2008cited by this paper
• CCR6 Regulates the Migration of Inflammatory and Regulatory T Cells1

  2008cited by this paper
• The search for endogenous activators of the aryl hydrocarbon receptor.

  2008cited by this paper
• Immunopathological aspects of age-related macular degeneration

  2008cited by this paper
• InnateDB: facilitating systems-level analyses of the mammalian innate immune response

  2008cited by this paper
• Oxidative damage–induced inflammation initiates age-related macular degeneration

  2008cited by this paper
• Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models.

  2007cited by this paper
• Interaction of retinal pigmented epithelial cells and CD4 T cells leads to T-cell anergy.

  2007cited by this paper
• Senescence regulates macrophage activation and angiogenic fate at sites of tissue injury in mice.

  2007cited by this paper
• Aggravation of intestinal inflammation by depletion/deficiency of γδ T cells in different types of IBD animal models

  2007cited by this paper
• Bovine and porcine transscleral solute transport: influence of lipophilicity and the Choroid-Bruch's layer.

  2006cited by this paper
• Macrophages Inhibit Neovascularization in a Murine Model of Age-Related Macular Degeneration

  2006cited by this paper
• γδ T Cells Promote Anterior Chamber-Associated Immune Deviation and Immune Privilege through Their Production of IL-101

  2006cited by this paper
• TRANSFAC® and its module TRANSCompel®: transcriptional gene regulation in eukaryotes

  2005cited by this paper
• Monocyte and macrophage heterogeneity

  2005cited by this paper
• The Immune Privilege of the Eye: Human Retinal Pigment Epithelial Cells Selectively Modulate T-Cell Activation In Vitro

  2005cited by this paper
• Rapid quantification of adult and developing mouse spatial vision using a virtual optomotor system.

  2004cited by this paper
• Immunoregulation in the tissues by gammadelta T cells.

  2003cited by this paper
• Regulatory lymphocytes: Immunoregulation in the tissues by γδ T cells

  2003cited by this paper
• Protection of the intestinal mucosa by intraepithelial γδ T cells

  2002cited by this paper
• Overexpressed Human Mitochondrial Thioredoxin Confers Resistance to Oxidant-induced Apoptosis in Human Osteosarcoma Cells*

  2002cited by this paper
• Gamma delta T cells are needed for ocular immune privilege and corneal graft survival.

  2001cited by this paper
• γδ T Cells Are Needed for Ocular Immune Privilege and Corneal Graft Survival1

  2001cited by this paper
• The role of Fas ligand in immune privilege

  2001cited by this paper
• Evidence that retinal pigment epithelium functions as an immune-privileged tissue.

  2000cited by this paper
• Role of gammadelta T cells in protecting normal airway function

  2000cited by this paper
• Paradoxical effects of IL-10 in endotoxin-induced uveitis.

  1995cited by this paper
• Homing and in situ differentiation of resident pulmonary lymphocytes.

  1994cited by this paper
• Recognition of self antigens by skin-derived T cells with invariant gamma delta antigen receptors.

  1991cited by this paper

• The Immunopathogenesis of uveitis

  2026cites this paper
• IL-23 drives uveitis by acting on a population of tissue-resident entheseal T cells

  2025cites this paper
• Role of MiR-204 in controlling metabolic functions of the subretinal microglia

  2025cites this paper
• Tissue-Specific Immune Transcriptional Signatures in the Bordering Tissues of the Mouse Retina and Brain

  2024cites this paper
• The gut–eye axis: from brain neurodegenerative diseases to age-related macular degeneration

  2024cites this paper
• Redefining our vision: an updated guide to the ocular immune system

  2024cites this paper
• Aryl hydrocarbon receptor (AhR)-mediated immune responses to degeneration of the retinal pigment epithelium.

  2024cites this paper
• Tissue-specific immune transcriptional signatures in the bordering tissues of the mouse brain and retina

  2024cites this paper
• Role of LIPIN 1 in regulating metabolic homeostasis in the retinal pigment epithelium

  2024cites this paper
• Assessing the role of T cells in response to retinal injury to uncover new therapeutic targets for the treatment of retinal degeneration

  2023cites this paper
• Current Data on the Age-Related Macular Degeneration Pathophysiology: Focus on Growth Factors and Neurotrophins

  2023cites this paper
• Mass cytometry reveals the corneal immune cell changes at single cell level in diabetic mice

  2023cites this paper
• Interleukin-17-mediated protective cytokine signaling against degeneration of the retinal pigment epithelium

  2023cites this paper
• Modulation of cGAS-STING signaling by PPARα in a mouse model of ischemia-induced retinopathy

  2022cites this paper
• [New findings on pathogenetic mechanisms in the development of age-related macular degeneration].

  2022cites this paper
• γδ T Cells in Brain Homeostasis and Diseases

  2022cites this paper
• Innate Immunity Dysregulation In Aging Eye and Therapeutic Interventions.

  2022cites this paper
• IL-4 induces reparative phenotype of RPE cells and protects against retinal neurodegeneration via Nrf2 activation

  2022cites this paper
• Intramuscular Vaccination With the HSV-1(VC2) Live-Attenuated Vaccine Strain Confers Protection Against Viral Ocular Immunopathogenesis Associated With γδT Cell Intracorneal Infiltration

  2021cites this paper
• The Cellular Composition of the Uveal Immune Environment

  2021cites this paper
• Potential Role of Myeloid-Derived Suppressor Cells (MDSCs) in Age-Related Macular Degeneration (AMD)

  2020cites this paper
• The Aryl Hydrocarbon Receptor: A Mediator and Potential Therapeutic Target for Ocular and Non-Ocular Neurodegenerative Diseases

  2020cites this paper
• MTOR‐initiated metabolic switch and degeneration in the retinal pigment epithelium

  2020cites this paper
• Exosomal MiRNA Transfer between Retinal Microglia and RPE

  2020cites this paper
• Neutrophils homing into the retina trigger pathology in early age-related macular degeneration

  2019cites this paper
• Age-related macular degeneration: A two-level model hypothesis

  2019cites this paper
• Deficiency of CRTH2, a Prostaglandin D2 Receptor, Aggravates Bleomycin‐induced Pulmonary Inflammation and Fibrosis

  2019cites this paper
• A Perspective of AMD Through the Eyes of Immunology.

  2018cites this paper
• Effects of aging and environmental tobacco smoke exposure on ocular and plasma circulatory microRNAs in the Rhesus macaque

  2018cites this paper