Ploidy status rarely changes in myeloma patients at disease progression.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis

• Publication date

  2006-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.LEUKRES.2005.07.004PMID 16111750
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A validated FISH trisomy index demonstrates the hyperdiploid and nonhyperdiploid dichotomy in MGUS.

  2005cited by this paper
• Genetics and Cytogenetics of Multiple Myeloma

  2004cited by this paper
• Both IGH translocations and chromosome 13q deletions are early events in monoclonal gammopathy of undetermined significance and do not evolve during transition to multiple myeloma

  2004cited by this paper
• Chromosomal abnormalities clustering in multiple myeloma reveals cytogenetic subgroups with nonrandom acquisition of chromosomal changes

  2004cited by this paper
• Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma

  2003cited by this paper
• The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma.

  2003cited by this paper
• Chromosome aberrations in solid tumors

  2003cited by this paper
• Multiple myeloma: evolving genetic events and host interactions

  2002cited by this paper
• Long‐term follow up with conventional cytogenetics and band 13q14 interphase/metaphase in situ hybridization monitoring in monoclonal gammopathies of undetermined significance

  2002cited by this paper
• Genomic abnormalities in monoclonal gammopathy of undetermined significance.

  2002cited by this paper
• Activating Ras mutations in patients with plasma-cell disorders: a reappraisal.

  2002cited by this paper
• Chromosomal alterations in ductal carcinomas in situ and their in situ recurrences.

  2000cited by this paper
• Deletions of chromosome 13q in monoclonal gammopathy of undetermined significance

  2000cited by this paper
• Is flow cytometric DNA content hypodiploidy prognostic in multiple myeloma?

  1999cited by this paper
• The addition of interferon or high dose cyclophosphamide to standard chemotherapy in the treatment of patients with multiple myeloma

  1999cited by this paper
• 14q32 translocations and monosomy 13 observed in monoclonal gammopathy of undetermined significance delineate a multistep process for the oncogenesis of multiple myeloma. Intergroupe Francophone du Myélome.

  1999cited by this paper
• Immunophenotypic and DNA content characteristics of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance.

  1999cited by this paper
• Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy.

  1998cited by this paper
• Chromosomal analysis in multiple myeloma: cytogenetic evidence of two different diseases

  1998cited by this paper
• A novel three-color, clone-specific fluorescence in situ hybridization procedure for monoclonal gammopathies.

  1998cited by this paper
• Absence of p53 deletions in bone marrow plasma cells of patients with monoclonal gammopathy of undedetermined significance

  1998cited by this paper
• Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer.

  1997cited by this paper
• Genetic changes in intraductal breast cancer detected by comparative genomic hybridization.

  1997cited by this paper
• DNA cell content studies in multiple myeloma.

  1996cited by this paper
• Activating mutations of N- and K-ras in multiple myeloma show different clinical associations: analysis of the Eastern Cooperative Oncology Group Phase III Trial.

  1996cited by this paper
• p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy

  1993cited by this paper
• Mutational activation of N- and K-ras oncogenes in plasma cell dyscrasias.

  1993cited by this paper
• p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy.

  1993cited by this paper
• R E V I E W a Rt I C L E

  year unknowncited by this paper
• CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Monosomy 13 Is Associated With the Transition of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma

  year unknowncited by this paper

• Flow Cytometric DNA Ploidy Analysis in Haemato-Lymphoid Neoplasms: An Analysis of 132 Cases

  2022cites this paper
• CNV Radar: an improved method for somatic copy number alteration characterization in oncology

  2020cites this paper
• Rapid assessment of hyperdiploidy in plasma cell disorders using a novel multi‐parametric flow cytometry method

  2019cites this paper
• The impact of NF-κB signaling on pathogenesis and current treatment strategies in multiple myeloma.

  2019cites this paper
• Clonal cytogenetics changes in progression of multiple myelomato extramedullary relapse and plasmocellular leukemia: a casereport

  2016cites this paper
• Plasma cell neoplasms: A morphologic, cytogenetic and immunophenotypic approach

  2015cites this paper
• Change in ploidy status from hyperdiploid to near-tetraploid in multiple myeloma associated with bortezomib/lenalidomide resistance.

  2014cites this paper
• Dissecting karyotypic patterns in non-hyperdiploid multiple myeloma: an overview on the karyotypic evolution.

  2013cites this paper
• Prognostic Implication of Genetic Changes (Cytogenetics, and FISH, Gains and Losses of DNA by SNP Array and aCGH) in Risk Stratification in Myeloma

  2013cites this paper
• Charakterisierung von Interleukin-16 als therapeutische Zielstruktur im Multiplen Myelom

  2013cites this paper
• DNA methylation of microRNA genes in multiple myeloma.

  2012cites this paper
• Karyotypic variability of human multiple myeloma cell lines

  2012cites this paper
• The t(4;14) translocation and FGFR3 overexpression in multiple myeloma: prognostic implications and current clinical strategies

  2012cites this paper
• Relapsed/Refractory multiple myeloma: defining refractory disease and identifying strategies to overcome resistance.

  2012cites this paper
• Molecular Biology and Classification of Multiple Myeloma

  2012cites this paper
• Molecular pathogenesis of multiple myeloma: chromosomal aberrations, changes in gene expression, cytokine networks, and the bone marrow microenvironment.

  2011cites this paper
• Hepatocyte growth factor, c-Met and syndecan-1 in multiple myeloma

  2011cites this paper
• Pathogenesis of myeloma.

  2011cites this paper
• The Basis and Rational Use of Molecular Genetic Testing in Mature B-cell Lymphomas

  2010cites this paper
• Near-tetraploidy clone can evolve from a hyperdiploidy clone and cause resistance to lenalidomide and bortezomib in a multiple myeloma patient.

  2010cites this paper
• International Myeloma Working Group molecular classification of multiple myeloma: spotlight review

  2009cites this paper
• Basic Biology of Plasma Cell Dyscrasias: Focus on the Role of the Tumor Microenviroment

  2008cites this paper
• Molecular pathogenesis of multiple myeloma.

  2007cites this paper
• Chromosome 13q deletion and IgH abnormalities may be both masked by near-tetraploidy in a high proportion of multiple myeloma patients: a combined morphology and I-FISH analysis.

  2007cites this paper
• Role of genetics in prognostication in myeloma.

  2007cites this paper
• Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets

  2007influential citation
• Sequential analysis of chromosome aberrations in multiple myeloma during disease progression.

  2007cites this paper
• A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy

  2007cites this paper