Metallothionein: historical review and perspectives.

No abstract is available for this paper.

• Publication year

  1979

• Venue

  Experientia. Supplementum

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1007/978-3-0348-6493-0_1PMID 400521
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Preparation and properties of the major copper-binding component in human fetal liver. Its identification as metallothionein.

  1978cited by this paper
• Human hepatic metallothioneins

  1974cited by this paper
• Equine hepatic and renal metallothioneins. Purification, molecular weight, amino acid composition, and metal content.

  1974cited by this paper
• Mercury binding in the kidney and liver of rats repeatedly exposed to mercuric chloride: induction of metallothionein by mercury and cadmium.

  1974cited by this paper
• Wilson's Disease: Identification of an Abnormal Copper-Binding Protein

  1973cited by this paper
• The -glutamyl cycle in the choroid plexus: its possible function in amino acid transport.

  1973cited by this paper
• Studies on the Induction of a Low-Molecular-Weight Zinc-Binding Protein in Rat Liver

  1973cited by this paper
• Biochemical effects of mercury, cadmium, and lead.

  1972cited by this paper
• Binding of cadmium ions by rat liver and kidney.

  1972cited by this paper
• Isolation and some properties of human metallothionein.

  1966cited by this paper
• Cadmium as a factor in hypertension

  1965cited by this paper
• [ON CADMIUM IN NORMAL HUMAN KIDNEYS WITH A REPORT ON THE ISOLATION OF METALLOTHIONEINE FROM CADMIUM-EXPOSED RABBIT LIVERS].

  1964cited by this paper
• THE EFFECTS OF COENZYMES AND SUBSTRATES ON THE RATE OF ZINC EXCHANGE IN HORSE LIVER ALCOHOL DEHYDROGENASE.

  1964cited by this paper
• Optically active metalloprotein chromophores. I. Metallothionein.

  1962cited by this paper
• Abnormal trace metals in man: cadmium.

  1961cited by this paper
• Metallothionein: a cadmium and zinc-containign protein from equine renal cortex. II. Physico-chemical properties.

  1961cited by this paper
• Metallothionein: a cadmium- and zinc-containing protein from equine renal cortex.

  1960cited by this paper
• Zinc and metalloenzymes.

  1955cited by this paper
• Principles of internal medicine

  1955cited by this paper
• Colorimetric Microdetermination of Cadmium with Dithizone

  1953cited by this paper
• Zinc in the mammalian organism, with particular reference to carbonic anhydrase.

  1949cited by this paper
• Carbonic anhydrase. Purification and nature of the enzyme.

  1940cited by this paper
• THE CRISIS AT BUITENZORG.

  1934cited by this paper
• Zinc in the nutrition of the rat.

  1933cited by this paper

• Metals and metallothionein evolution in snails: a contribution to the concept of metal-specific functionality from an animal model group

  2024cites this paper
• Zinc in Human Health and Infectious Diseases

  2022cites this paper
• Zinc Status Impacts the Epidermal Growth Factor Receptor and Downstream Protein Expression in A549 Cells

  2022cites this paper
• The Enigmatic Metallothioneins: A Case of Upward-Looking Research

  2021cites this paper
• The Bioinorganic Chemistry of Mammalian Metallothioneins.

  2021cites this paper
• Zinc as a Neuroprotective Nutrient for COVID-19–Related Neuropsychiatric Manifestations: A Literature Review

  2021cites this paper
• Metallothionein 2A Gene Polymorphisms in Relation to Diseases and Trace Element Levels in Humans

  2020cites this paper
• Forgotten partners and function regulators of inducible metallothioneins

  2019cites this paper
• Further insights into the metal ion binding abilities and the metalation pathway of a plant metallothionein from Musa acuminata

  2017cites this paper
• Zinc as a Gatekeeper of Immune Function

  2017cites this paper
• Expression of metallothioneins in placental and fetal tissues in undisturbed and PGM-Zn treated syngeneic pregnancy

  2015cites this paper
• The Critical Roles of Zinc: Beyond Impact on Myocardial Signaling

  2015cites this paper
• Estudo metaloproteômico do mércurio em amostras de tecido hepático de peixes coletados na área de influência do AHE JIRAU - Bacia do rio Madeira

  2014cites this paper
• Cd modifies hepatic Zn deposition and modulates δ‐ALA‐D activity and MT levels by distinct mechanisms

  2012cites this paper
• Chemistry and biology of mammalian metallothioneins

  2011cites this paper
• Influence of certain chelating agents on egress of cadmium from cultured epithelial cells containing high amounts of metallothionein: a screening of Cd-releasing and toxic effects.

  2009cites this paper
• Selênio em tilápia do Nilo utilizando eletroforese em gel e espectrometria atômica

  2009cites this paper
• UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL INSTITUTO DE CIÊNCIAS BÁSICAS DA SAÚDE CURSO DE PÓS-GRADUAÇÃO EM CIÊNCIAS BIOLÓGICAS: BIOQUÍMICA AVALIAÇÃO DA ATIVIDADE DA δ-AMINOLEVULINATO-DESIDRATASE E CONCENTRAÇÃO DE METALOTIONEÍNA EM FÍGADO E ENCÉFALO DE RATOS EXPOSTOS A CÁDMIO E ZINCO

  2009cites this paper
• UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL INSTITUTO DE CIÊNCIAS BÁSICAS DA SAÚDE CURSO DE PÓS-GRADUAÇÃO EM CIÊNCIAS BIOLÓGICAS: BIOQUÍMICA AVALIAÇÃO DA ATIVIDADE DA δ-AMINOLEVULINATO-DESIDRATASE E CONCENTRAÇÃO DE METALOTIONEÍNA EM FÍGADO E ENCÉFALO DE RATOS

  2009influential citation
• Metallothioneins are multipurpose neuroprotectants during brain pathology

  2006cites this paper
• The metallobiochemistry of zinc enzymes.

  2006cites this paper
• Shell weight as an independent variable in relation to cadmium content of molluscs MARINE ECOLOGY -

  2006cites this paper
• Arsenic binding to Fucus vesiculosus metallothionein.

  2004cites this paper
• Protective role of zinc-metallothionein (Zn-MT) in iron nitrilotriacetate (Fe-NTA)-induced renal oxidative damage

  2003cites this paper
• Nuclear proteins that bind to metal response element a (MREa) in the Wilson disease gene promoter are Ku autoantigens and the Ku-80 subunit is necessary for basal transcription of the WD gene.

  2002cites this paper
• Metal regulation of metallothionein participation in redox reactions

  1999cites this paper
• Effect of melatonin on cadmium-induced hepatotoxicity in male Sprague-Dawley rats.

  1998cites this paper
• The glutathione redox couple modulates zinc transfer from metallothionein to zinc-depleted sorbitol dehydrogenase.

  1998cites this paper
• Thiolate ligands in metallothionein confer redox activity on zinc clusters.

  1998cites this paper
• Recent excitement regarding metallothionein.

  1998cites this paper
• The ATP-metallothionein complex.

  1998cites this paper
• Developmental Neurotoxicity of Cadmium

  1998cites this paper
• Chapter 30 – Developmental Neurotoxicity of Cadmium

  1998cites this paper
• Primary structure of a myohemerythrin-like cadmium-binding protein, isolated from a terrestrial annelid oligochaete.

  1997cites this paper
• Binding of Cd to metallothionein in the placenta of Cd-treated mouse.

  1996cites this paper
• Free amino acids as a biochemical indicator of stress in the estuarine bivalve Macoma balthica

  1996cites this paper
• Covalent sequestration of melphalan by metallothionein and selective alkylation of cysteines.

  1995cites this paper
• Selenium lethality: role of glutathione and metallothionein.

  1993cites this paper
• Zinc: biological functions and coordination motifs

  1993cites this paper
• Arsenic-Copper Interaction in the Kidney of the Rat

  1992cites this paper
• Zinc rapidly induces a metal response element-binding factor.

  1992cites this paper
• Introduction to metallothionein.

  1991cites this paper
• Defense of mammalian body against heavy metal-induced toxicities: Sequestration by the choroid plexus and elimination via the bile.

  1991cites this paper
• Zinc transfer from transcription factor IIIA fingers to thionein clusters.

  1991cites this paper
• Copper metallothionein in patients with hepatic copper overload

  1991cites this paper
• Overview of metallothionein.

  1991cites this paper
• Metallothionein separation and analysis by reversed phase high performance liquid chromatography coupled with graphite furnace atomic absorption spectrometry

  1991cites this paper
• Metallothionein and Metallothionein-Like Proteins: Physiological Importance

  1989cites this paper
• Pollutant Toxicity to Aquatic Animals - Methods of Study and Their Applications

  1989cites this paper
• Copper and zinc toxicity in Ephydatia fluviatilis (Porifera: spongillidae)

  1988cites this paper
• Primary Structure of Striped Dolphin Renal Metallothionein II

  1988cites this paper
• Oncogenicity of rat prostate cells transformed in vitro with cadmium chloride

  1988cites this paper
• Glutathione, a first line of defense against cadmium toxicity

  1987cites this paper
• NMR analysis of the structure and metal sequestering properties of metallothioneins.

  1987cites this paper
• Role of Metallothionein in Cadmium Metabolism

  1986cites this paper
• Development of fetal mineral and trace element metabolism in rats with normal as well as magnesium- and zinc-deficient diets

  1986cites this paper
• Copper-binding proteins in liver of bluegills exposed to increased soluble copper under field and laboratory conditions.

  1986cites this paper
• Mercury-binding proteins from the marine mussel, Mytilus edulis.

  1986cites this paper
• Unique properties of Cd-binding peptides induced in fission yeast, Schizosaccharomyces pombe.

  1986cites this paper
• Induction of Low Molecular Weight Cadmium-Binding Compound in Soybean Roots

  1986cites this paper
• A preliminary study of Cu-, Cd- and Zn-binding components in the hepatopancreas of Palaemon elegans (Crustacea: Decapoda).

  1986cites this paper
• Cadmium

  1986cites this paper
• The Influence of Chemical Species on the Absorption and Physiological Utilization of Trace Elements from the Diet or Environment

  1986cites this paper
• Quantitation of chick tissue zinc-metallothionein by gel electrophoresis and silver stain enhancement.

  1986cites this paper
• The chronic toxicity of equine cadmium metallothionein in the rat

  1985cites this paper
• DETOXIFICATION OF COPPER IN THE CELLS OF THE DIGESTIVE GLAND OF MUSSEL: THE ROLE OF LYSOSOMES AND THIONEINS

  1985cites this paper
• Effect of dietary cadmium on serum and liver lipids in mice in relation to interaction of essential metals, zinc, copper and iron.

  1984cites this paper
• Metallothionein: structure/antigenicity and detection/quantitation in normal physiological fluids.

  1984cites this paper
• A modified Lowry assay to measure levels of proteins lacking aromatic amino acid residues (e.g. metallothioneins).

  1984cites this paper
• Subcellular distribution of heavy metals in liver and kidney of a narwhal whale (Monodon monoceros): an evaluation for the presence of metallothionein.

  1984cites this paper
• NMR analysis of the structure and metal sequestering properties of metallothioneins.

  1984cites this paper
• A low-molecular-weight cadmium-binding substance in human and rat livers and human blood.

  1984cites this paper
• Metallothionein and mercury tolerance in the killifish, fundulus heteroclitus

  1984cites this paper
• The role of digestion in the black sea bass, Centropristis striata, on the chemical speciation of organically bound cadmium.

  1984cites this paper
• Subcellular distribution and binding of heavy metals in the untreated liver of the squid; comparison with data from the livers of cadmium and silver-exposed rats

  1983cites this paper
• Toxicity and Tolerance in the Responses of Plants to Metals

  1983cites this paper
• Isolation, characterization and induction of metallothionein in the stonefly Eusthenia spectabilis following exposure to cadmium

  1983cites this paper
• Immunohistochemical localization of metallothionein in cell nucleus and cytoplasm of rat liver and kidney.

  1982cites this paper
• Heavy metals in Tasmanian shellfish. 2 — The influence of heavy metal ratios on the accumulation and detoxification mechanisms in rats fed contaminated oysters

  1982cites this paper
• Metallothione in-like protein in lobsters ()

  1981cites this paper
• Chelation of cadmium with BAL and DTPA in rats

  1980cites this paper
• Metallothionein and other low molecular weight metal-binding proteins. report from the "first international meeting on metallothionein and other low molecular weight metal-binding proteins".

  1979cites this paper