A low-speed centrifugation concept leads to cell accumulation and vascularization of solid platelet-rich fibrin: an experimental study in vivo

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Platelets

• Publication date

  2019-04-03

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1080/09537104.2018.1445835PMID 29509050
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reduction of the relative centrifugal force influences cell number and growth factor release within injectable PRF-based matrices

  2017cited by this paper
• Reduction of relative centrifugal forces increases growth factor release within solid platelet-rich-fibrin (PRF)-based matrices: a proof of concept of LSCC (low speed centrifugation concept)

  2017cited by this paper
• Reduction of relative centrifugation force within injectable platelet-rich-fibrin (PRF) concentrates advances patients’ own inflammatory cells, platelets and growth factors: the first introduction to the low speed centrifugation concept

  2017cited by this paper
• What Is the Biological and Clinical Relevance of Fibrin?

  2016cited by this paper
• Comparative release of growth factors from PRP, PRF, and advanced-PRF

  2016cited by this paper
• Monocyte preseeding leads to an increased implant bed vascularization of biphasic calcium phosphate bone substitutes via vessel maturation.

  2016cited by this paper
• Addition of blood to a phycogenic bone substitute leads to increased in vivo vascularization

  2015cited by this paper
• Crosstalk between platelets and PBMC: New evidence in wound healing

  2015cited by this paper
• Efficacy of platelet rich fibrin in the reduction of the pain and swelling after impacted third molar surgery: Randomized multicenter split-mouth clinical trial

  2015cited by this paper
• Non‐invasive in vivo tracking of fibrin degradation by fluorescence imaging

  2015cited by this paper
• Boon and Bane of Inflammation in Bone Tissue Regeneration and Its Link with Angiogenesis

  2015cited by this paper
• Advanced platelet-rich fibrin: a new concept for cell-based tissue engineering by means of inflammatory cells.

  2014cited by this paper
• Follow-Up of Implant Survival Comparing Ficoll and Bone Marrow Aspirate Concentrate Methods for Hard Tissue Regeneration with Mesenchymal Stem Cells in Humans

  2014cited by this paper
• Dual Role of the Leukocyte Integrin αMβ2 in Angiogenesis

  2014cited by this paper
• Monocyte Exosomes Stimulate the Osteogenic Gene Expression of Mesenchymal Stem Cells

  2013cited by this paper
• Bone marrow aspirate concentrate used with bovine bone mineral to reconstruct vertical and horizontal mandibular defects: report of two techniques.

  2013cited by this paper
• Neutrophil recruitment and function in health and inflammation

  2013cited by this paper
• Preparation method and growth factor content of platelet concentrate influence the osteogenic differentiation of bone marrow stromal cells.

  2013cited by this paper
• Efficacy of Leukocyte- and Platelet-Rich Fibrin in Wound Healing: A Randomized Controlled Clinical Trial

  2012cited by this paper
• Second-generation platelet concentrate (PRF) as a pulpotomy medicament in a permanent molar with pulpitis: a case report.

  2012cited by this paper
• Recent advances in the development of GTR/GBR membranes for periodontal regeneration--a materials perspective.

  2012cited by this paper
• Evaluation of the tissue reaction to a new bilayered collagen matrix in vivo and its translation to the clinic

  2011cited by this paper
• Effects of platelet-rich fibrin on human periodontal ligament fibroblasts and application for periodontal infrabony defects.

  2011cited by this paper
• Rapid vascularization of starch–poly(caprolactone) in vivo by outgrowth endothelial cells in co‐culture with primary osteoblasts

  2011cited by this paper
• Scaffold vascularization in vivo driven by primary human osteoblasts in concert with host inflammatory cells.

  2011cited by this paper
• Fine‐tuning scaffolds for tissue regeneration: effects of formic acid processing on tissue reaction to silk fibroin

  2010cited by this paper
• The rapid anastomosis between prevascularized networks on silk fibroin scaffolds generated in vitro with cocultures of human microvascular endothelial and osteoblast cells and the host vasculature.

  2010cited by this paper
• The 3R principle and the use of non-human primates in the study of neurodegenerative diseases: the case of Parkinson's disease.

  2009cited by this paper
• Contribution of outgrowth endothelial cells from human peripheral blood on in vivo vascularization of bone tissue engineered constructs based on starch polycaprolactone scaffolds.

  2009cited by this paper
• In Vivo Comparison of Hard Tissue Regeneration with Human Mesenchymal Stem Cells Processed with Either the FICOLL Method or the BMAC Method

  2009cited by this paper
• Dynamic processes involved in the pre-vascularization of silk fibroin constructs for bone regeneration using outgrowth endothelial cells.

  2009cited by this paper
• Platelet-Rich Plasma: A Review of Biology and Applications in Plastic Surgery

  2006cited by this paper
• Current Applications of Platelet Gels in Facial Plastic Surgery

  2002cited by this paper
• Une opportunite´ en paro-implantologie: Le PRF

  2001cited by this paper
• Vascular endothelial growth factor binds to fibrinogen and fibrin and stimulates endothelial cell proliferation.

  2000cited by this paper
• Guided Tissue Regeneration Using Bioresorbable and Non-Resorbable Devices: Initial Healing and Long-Term Results.

  1993cited by this paper
• Guided tissue regeneration using bioresorbable and non-resorbable devices: initial healing and long-term results.

  1993cited by this paper

• Effectiveness of Autologous Plasma Rich in Growth Factors on Healing of Extraction Socket—A Systematic Review

  2026cites this paper
• Granulocytes and their Involvement in the Foreign Body Response to Biomaterials and Tissue Repair

  2026cites this paper
• Comparative Evaluation of Injectable Platelet-Rich Fibrin with and Without Microneedling in Periodontal Regeneration: A Prospective Split-Mouth Clinical Study

  2026cites this paper
• Comparative evaluation of mechanical properties of leukocyte rich platelet rich fibrin, advanced-platelet rich fibrin, titanium-platelet rich fibrin, selphyl platelet rich fibrin matrix and merisis platelet rich fibrin matrix

  2025cites this paper
• The Impact of Centrifugation Devices and Collection Tubes on Fibrin Characteristics and Growth Factor Release Under High- and Low-Speed Protocols

  2025cites this paper
• Comparative proteomic profiling of advanced, injectable, and titanium-prepared platelet rich fibrins (PRF): Insights into functional divergence and clinical potential.

  2025cites this paper
• ADVANCED PLATELET-RICH FIBRIN (A-PRF+): BIOLOGICAL RATIONALE, PREPARATION PROTOCOLS, AND CLINICAL APPLICATIONS IN ORAL REGENERATIVE THERAPY

  2025cites this paper
• Preclinical Evaluation of the Effect of Liquid Platelet–Rich Fibrin and a Volume‐Stable Collagen Matrix on Periodontal Regeneration

  2025cites this paper
• THE RESULTS OF USING A COMBINED DEMINERALIZED FIBRIN-BONE MATRIX IN THE TREATMENT OF RADICULAR CYSTS OF THE JAWS

  2025cites this paper
• Optimizing methods for regenerative endodontics

  2025cites this paper
• Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization

  2025cites this paper
• COMPARATIVE ANALYSIS OF THE RESULTS OF COMBINED MINERALISED AND DEMINERALISED FIBRIN-BONE SCAFFOLDS USE IN SINUS-LIFT TECHNIQUE

  2025cites this paper
• THE EFFECTIVENESS OF USING A COMBINED FIBRIN-BONE SCAFFOLD FOR BONE TISSUE REPAIR IN JAW DEFECTS

  2025cites this paper
• Efficacy of leukocyte-platelet rich fibrin (L-PRF) plug in accelerating the maxillary canine retraction in young adults: A split mouth randomized controlled trial

  2025cites this paper
• ANALYSIS OF THE EFFECTIVENESS OF THE DEVELOPED TECHNIQUE FOR THE SIMULTANEOUS FORMATION OF A COMBINED FIBRIN- OSSEOUS SCAFFOLD USING THE SINUS LIFT TECHNIQUE

  2025cites this paper
• Advantages of horizontal centrifugation of platelet-rich fibrin in regenerative medicine and dentistry.

  2025cites this paper
• CLINICAL AND EXPERIMENTAL RATIONALE FOR THE FEASIBILITY OF USING A COMBINED FIBRIN–BONE SCAFFOLD WITH A PRONOUNCED LOCAL ANTIMICROBIAL EFFECT

  2025cites this paper
• The effect of vitamin E incorporated into injectable platelet-rich fibrin on orthodontic tooth movement in rabbits.

  2024cites this paper
• APRF+ BIOMATERIALS IN DENTISTRY: MECHANISMS, CLINICAL APPLICATIONS AND PERSPECTIVES

  2024cites this paper
• The biological edge in periodontal therapy: Revolutionizing periodontal treatment with autologous blood products

  2024cites this paper
• Use of autologous tissue regeneration matrix (pro prf) in the treatment of diabetic ulcers: case series

  2024cites this paper
• Assessing the Effectiveness of A-PRF+ for Treating Periodontal Defects: A Prospective Interventional Pilot Study Involving Smokers

  2024cites this paper
• [Use of platelet-rich fibrin in periodontal surgery].

  2024cites this paper
• The effect of injectable platelet-rich fibrin and platelet-rich fibrin in regenerative endodontics: a comparative in vitro study

  2024cites this paper
• Leukocyte- and Platelet-Rich Fibrin versus commercially available fibrin sealants in elective cranial surgery: a cost-effectiveness analysis.

  2024cites this paper
• Platelet-rich fibrin as an autologous biomaterial for bone regeneration: mechanisms, applications, optimization.

  2024cites this paper
• Differences between first‐ and second‐generation autologous platelet concentrates

  2024cites this paper
• Recent trends in polymer-based nanocomposites and its application in bone tissue engineering

  2024cites this paper
• Platelet rich fibrin as a bioactive matrix with proosteogenic and proangiogenic properties on human healthy primary cells in vitro

  2024cites this paper
• Fibrin Network and Platelets Densities in Platelet-Rich Fibrin (PRF) Membranes Produced from Plastic Tubes Without Additives: A New Approach to PRF Clinical Use

  2024cites this paper
• Evolution and Clinical Advances of Platelet-Rich Fibrin in Musculoskeletal Regeneration

  2023influential citation
• Progressive Platelet Rich Fibrin tissue regeneration matrix: Description of a novel, low cost and effective method for the treatment of chronic diabetic ulcers—Pilot study

  2023cites this paper
• Guided bone regeneration in implant dentistry: Basic principle, progress over 35 years, and recent research activities.

  2023cites this paper
• Ultrasonic osteotomy and regeneration with A-PRF+ for periapical surgery of a mandibular molar with root cyst perforating the lingual osseous cortex: A case report

  2023cites this paper
• Estimation of the Mechanical Properties of PRF in the Implant Surgery: An Original Research

  2023cites this paper
• Effect of leukocyte-platelet-rich fibrin (L-PRF) on the rate of orthodontic tooth movement and expression of various biomarkers in gingival crevicular fluid

  2023cites this paper
• Porous Zirconia Blocks Embedded with Platelet Rich Fibrin for Enhanced Bone Healing: Mechanical and Morphological Assessment

  2023cites this paper
• The Role of Leukocyte and Platelet-Rich Fibrin in Enhancing the Healing of Extraction Sockets: An Overview of the Literature

  2023cites this paper
• Can platelet-rich fibrin act as a natural carrier for antibiotics delivery? A proof-of-concept study for oral surgical procedures

  2023cites this paper
• Injectable Platelet-Rich Fibrin in Contact with Bone Substitutes, Porous Zirconia, or Laser-Textured Implant Surfaces: A Detailed Morphological Analysis

  2023cites this paper
• Comparative histological evaluation of two PRF formulations (PRF High and PRF Medium) on quality of life and healing outcome of apicomarginal defects: A randomized clinical trial.

  2023cites this paper
• Vérlemezkében gazdag fibrinnel kezelt parodontalis csontdefektusok gyógyulásának értékelése

  2022cites this paper
• Evaluation of mechanical properties of platelet-rich fibrin membrane for implant surgery: An analysis in vitro

  2022cites this paper
• Liquid Platelet-Rich Fibrin Coating Implant Surface to Enhance Osseointegration: A Double-Blinded, Randomized Split-Mouth Trial with 1-Year Follow-up.

  2022cites this paper
• Healing of periodontal intrabony defects following treatment with a new-generation platelet-rich fibrin.

  2022cites this paper
• Tensile Strength Essay Comparing Three Different Platelet-Rich Fibrin Membranes (L-PRF, A-PRF, and A-PRF+): A Mechanical and Structural In Vitro Evaluation

  2022cites this paper
• The effect of resting and compression time post-centrifugation on the characteristics of platelet rich fibrin (PRF) membranes

  2022cites this paper
• Comparison of the effects of platelet concentrates produced by high and low-speed centrifugation protocols on the healing of critical-size defects in rat calvaria: a microtomographic and histomorphometric study

  2022cites this paper
• Comparative Evaluation of Clinical Efficacy of Leukocyte-Rich Platelet-Rich Fibrin with Advanced Platelet-Rich Fibrin in Management of Gingival Recession Defects: A Randomized Controlled Trial

  2022cites this paper
• Platelet-Rich Fibrin Progressive Protocol: Third Generation of Blood Concentrates.

  2022cites this paper
• Solid PRF Serves as Basis for Guided Open Wound Healing of the Ridge after Tooth Extraction by Accelerating the Wound Healing Time Course—A Prospective Parallel Arm Randomized Controlled Single Blind Trial

  2022cites this paper
• Vérlemezkében gazdag fibrinnel kezelt parodontalis csontdefektusok gyógyulásának értékelése

  2022cites this paper
• Perbandingan Perubahan Luas Luka dan Angiogenesis pada Luka Bakar Derajat IIB Tikus Sprague Dawley yang Diberikan Advanced Platelet-rich Fibrin dan Advanced Platelet-rich Fibrin Plus

  2021influential citation
• Efficacy of platelet-rich fibrin in promoting the healing of extraction sockets: a systematic review

  2021cites this paper
• Microneedling with injectable platelet-rich fibrin for facial rejuvenation

  2021cites this paper
• Temporomandibular joint biosupplementation using platelet concentrates: a narrative review

  2021cites this paper
• A Standardized g-Force Allows the Preparation of Similar Platelet-Rich Fibrin Qualities Regardless of Rotor Angle

  2021influential citation
• Efficacy of i-PRF in regenerative endodontics therapy for mature permanent teeth with pulp necrosis: study protocol for a multicentre randomised controlled trial

  2021cites this paper
• Automatic medium exchange for micro‐volume cell samples based on dielectrophoresis

  2021cites this paper
• Modification of collagen-based sponges can induce an upshift of the early inflammatory response and a chronic inflammatory reaction led by M1 macrophages: an in vivo study

  2020cites this paper
• Treatment of apicomarginal defect with periapical surgery: A case report

  2020cites this paper
• Antibacterial effects of platelet-rich fibrin produced by horizontal centrifugation

  2020cites this paper
• Lower facial regeneration with a combination of platelet‐rich fibrin liquid matrices based on the low speed centrifugation concept‐Cleopatra technique

  2020cites this paper
• Methodological variations affect the release of VEGF in vitro and fibrinolysis’ time from platelet concentrates

  2020cites this paper
• Advanced -PRF: Clinical evaluation in impacted mandibular third molar sockets.

  2020cites this paper
• Autologes „platelet-rich fibrin“ zur Unterstützung von Hart- und Weichgewebsheilung

  2020cites this paper
• Traumatic Bone Cyst in the Mandible Regenerated with Platelet-Rich Fibrin: a Case Report.

  2020cites this paper
• Telomere length and genetic variations affecting telomere length as biomarkers for facial regeneration with platelet‐rich fibrin based on the low‐speed centrifugation concept

  2019cites this paper
• Application of Platelet Rich Fibrin in the Regeneration of Intra Oral Defects: A Systematic Review

  2019cites this paper
• The role of centrifugation process in the preparation of therapeutic blood concentrates: Standardization of the protocols to improve reproducibility

  2019cites this paper
• Platelet-Rich Fibrin as a Bone Graft Material in Oral and Maxillofacial Bone Regeneration: Classification and Summary for Better Application

  2019cites this paper
• Pain and quality of life after endodontic surgery with or without advanced platelet-rich fibrin membrane application: a randomized clinical trial

  2019cites this paper
• Anti-inflammation effects of injectable platelet-rich fibrin via macrophages and dendritic cells.

  2019cites this paper
• Efficacy of Platelet-Rich Fibrin in Secondary Cleft Alveolar Bone Grafting

  2019cites this paper
• Biomaterial-based bone regeneration and soft tissue management of the individualized 3D-titanium mesh: An alternative concept to autologous transplantation and flap mobilization.

  2019cites this paper
• Platelet‐rich fibrin elicits an anti‐inflammatory response in macrophages in vitro

  2019cites this paper
• Comparison of platelet-rich fibrin (PRF) produced using 3 commercially available centrifuges at both high (~ 700 g) and low (~ 200 g) relative centrifugation forces

  2019cites this paper
• A novel method for evaluating and quantifying cell types in platelet rich fibrin and an introduction to horizontal centrifugation.

  2019cites this paper
• Standardization of relative centrifugal forces in studies related to platelet-rich fibrin.

  2019cites this paper
• A Proof of the Low Speed Centrifugation Concept in Rodents: New Perspectives for In Vivo Research

  2018cites this paper
• The effect of age, gender, and time between blood draw and start of centrifugation on the size outcomes of platelet-rich fibrin (PRF) membranes

  2018cites this paper
• Controversies related to scientific report describing g-forces from studies on platelet-rich fibrin: Necessity for standardization of relative centrifugal force values

  2018cites this paper
• Homogeneous pressure influences the growth factor release profiles in solid platelet-rich fibrin matrices and enhances vascular endothelial growth factor release in the solid platelet-rich fibrin plugs

  2018cites this paper
• L-PRF - Uma Nova tendÊncia de Regeneração Tecidular

  2018cites this paper
• Application of liquid platelet-rich fibrin for treating hyaluronic acid-related complications: A case report with 2 years of follow-up

  2018cites this paper
• Sinus Augmentation Using Platelet-Rich Fibrin With or Without a Bone Graft: What Is the Consensus?

  2018cites this paper
• Influence of concentration and preparation of platelet rich fibrin on human bone marrow mononuclear cells (in vitro)

  2018cites this paper
• Autologes Blutkonzentrat zur Unterstützung der Regeneration – Platelet

  year unknowncites this paper