Strong immunostimulatory activity of AT‐oligodeoxynucleotide requires a six‐base loop with a self‐stabilized 5′‐C…G‐3′ stem structure

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Cellular Microbiology

• Publication date

  2006-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1462-5822.2005.00640.xPMID 16469059
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Probiotics Ameliorate Recurrent Th1-Mediated Murine Colitis by Inducing IL-10 and IL-10-Dependent TGF-β-Bearing Regulatory Cells1

  2005cited by this paper
• Pathogen recognition with Toll-like receptors.

  2005cited by this paper
• [Toll-like receptor].

  2005cited by this paper
• Toll-like receptor 9 is expressed on follicle-associated epithelia containing M cells in swine Peyer's patches.

  2005cited by this paper
• Toll-like receptor 2 is expressed on the intestinal M cells in swine.

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• Cutting Edge: Species-Specific TLR9-Mediated Recognition of CpG and Non-CpG Phosphorothioate-Modified Oligonucleotides1

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• Strong immunostimulation in murine immune cells by Lactobacillus rhamnosus GG DNA containing novel oligodeoxynucleotide pattern

  2005cited by this paper
• Augmentation of T(H)-1 type response by immunoactive AT oligonucleotide from lactic acid bacteria via Toll-like receptor 9 signaling.

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• Development of immune assay system for both CpG and non‐CpG DNA from lactic acid bacteria using a transfectant of swine Toll‐like receptor 9

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  2004cited by this paper
• Immunotherapeutic uses of CpG oligodeoxynucleotides

  2004influential reference
• Dextran from Leuconostoc mesenteroides augments immunostimulatory effects by the introduction of phosphate groups.

  2004cited by this paper
• Strong Cytosine-Guanosine-Independent Immunostimulation in Humans and Other Primates by Synthetic Oligodeoxynucleotides with PyNTTTTGT Motifs

  2003influential reference
• Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

  2003cited by this paper
• Immunostimulatory oligonucleotide, CpG-like motif exists in Lactobacillus delbrueckii ssp. bulgaricus NIAI B6.

  2003cited by this paper
• Swine Toll-like receptor 9(1) recognizes CpG motifs of human cell stimulant.

  2003cited by this paper
• CpG DNA: recognition by and activation of monocytes.

  2002cited by this paper
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  2002cited by this paper
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  2002cited by this paper
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  2001cited by this paper
• Response of porcine peripheral blood mononuclear cells to CpG-containing oligodeoxynucleotides.

  2001influential reference
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  2000influential reference
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• Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells.

  2000influential reference
• Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.

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  1997cited by this paper
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  1997influential reference
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  1997cited by this paper
• Mitogenicity of DNA from different organisms for murine B cells.

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  1996cited by this paper
• Bacterial DNA induces murine interferon-gamma production by stimulation of interleukin-12 and tumor necrosis factor-alpha.

  1996cited by this paper
• Macrophages ingest and are activated by bacterial DNA.

  1996cited by this paper
• CpG motifs in bacterial DNA trigger direct B-cell activation

  1995cited by this paper

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  2023cites this paper
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  2021cites this paper
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  2020cites this paper
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  2013cites this paper
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  2012cites this paper
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  2011influential citation
• Taking the sting out of malaria.

  2011influential citation
• Lactic acid bacteria in the prevention of pneumococcal respiratory infection: future opportunities and challenges.

  2011cites this paper
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