5-HT2A Receptor Activation Leads to Increased BDNF mRNA expression in C6 glioma cells

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Neuromolecular medicine

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1385/NMM:1:3:197PMID 12095161
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

  2001cited by this paper
• Differential Sorting of Nerve Growth Factor and Brain-Derived Neurotrophic Factor in Hippocampal Neurons

  1999cited by this paper
• Molecular mechanisms underlying activity-dependent regulation of BDNF expression.

  1999cited by this paper
• Manipulations of brain 5-HT levels affect gene expression for BDNF in rat brain.

  1999cited by this paper
• 5-Hydroxytryptamine2A receptor stimulation induces activator protein-1 and cyclic AMP-responsive element binding with cyclic AMP-responsive element-binding protein and Jun D as common components in cerebellar neurons.

  1999cited by this paper
• Modulation of Nigrostriatal Dopaminergic Transmission by Antisense Oligodeoxynucleotide Against Brain-Derived Neurotrophic Factor

  1998cited by this paper
• Attenuation of the seizure‐induced expression of BDNF mRNA in adult rat brain by an inhibitor of calcium/calmodulin‐dependent protein kinases

  1998cited by this paper
• Expression of mRNAs encoding BDNF and its receptor in adult rat hypothalamus

  1998cited by this paper
• Identification of a signaling pathway involved in calcium regulation of BDNF expression.

  1998influential reference
• Localization of putative calcium-responsive regions in the rat BDNF gene.

  1997influential reference
• Intracellular Ca2+ signals induced by ATP and thapsigargin in glioma C6 cells. Calcium pools sensitive to inositol 1,4,5-trisphosphate and thapsigargin.

  1997cited by this paper
• Brain‐Derived Neurotrophic Factor Increases the Stimulation‐Evoked Release of Glutamate and the Levels of Exocytosis‐Associated Proteins in Cultured Cortical Neurons from Embryonic Rats

  1997cited by this paper
• Extracellular Calcium Sensing by Glial Cells: Low Extracellular Calcium Induces Intracellular Calcium Release and Intercellular Signaling

  1997cited by this paper
• Mechanism Involved in Initiation and Propagation of Receptor-Induced Intercellular Calcium Signaling in Cultured Rat Astrocytes

  1997cited by this paper
• 5-HT2A Receptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex

  1997influential reference
• BDNF gene can Be activated by Ca2+ signals without involvement of de novo AP-1 synthesis.

  1996cited by this paper
• Neurotrophins Stimulate the Release of Dopamine from Rat Mesencephalic Neurons via Trk and p75Lntr Receptors*

  1996cited by this paper
• Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

  1995cited by this paper
• Characterization of the 5-hydroxytryptamine2A receptor-activated cascade in rat C6 glioma cells.

  1995cited by this paper
• Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments

  1995cited by this paper
• Alternate 5' exons in the rat brain-derived neurotrophic factor gene: differential patterns of expression across brain regions.

  1994cited by this paper
• Cyclic AMP Decreases the Expression of a Neuronal Marker (GAD67) and Increases the Expression of an Astroglial Marker (GFAP) in C6 Cells

  1994cited by this paper
• Thapsigargin: potent inhibitor of Ca2+ transport ATP-ases of endoplasmic and sarcoplasmic reticulum.

  1993cited by this paper
• A rapid optimized protocol for downward alkaline Southern blotting of DNA.

  1993cited by this paper
• Multiple promoters direct tissue-specific expression of the rat BDNF gene.

  1993influential reference
• Regulation of brain-derived neurotrophic factor and nerve growth factor mRNA in primary cultures of hippocampal neurons and astrocytes

  1992influential reference
• CREB: a Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases.

  1991influential reference
• Serotonin regulates cytosolic Ca2+ activity and membrane potential in a neuronal and in a glial cell line via 5-HT3 and 5-HT2 receptors by different mechanisms.

  1989cited by this paper
• Turnover of beta 1- and beta 2-adrenergic receptors after down-regulation or irreversible blockade.

  1986cited by this paper

• Targeting the serotonergic system in the treatment of neurodegenerative diseases—emerging therapies and unmet challenges

  2025cites this paper
• The excitatory milieu in glioma: mechanisms and therapeutic avenues.

  2025cites this paper
• Short and long-term blockades of adenosine 2A, 5-HT2A, and 5-HT7 receptors induce apoptosis, reduce proliferation, and show differential effects on miR-27b-3p expression in neuroblastoma cell lines.

  2024cites this paper
• Mesenchymal stem cell-derived conditioned medium and Methysergide give rise to crosstalk inhibition of 5-HT2A and 5-HT7 receptors in neuroblastoma cells.

  2023cites this paper
• Neural Plasticity in the Ventral Tegmental Area, Aversive Motivation during Drug Withdrawal and Hallucinogenic Therapy

  2022cites this paper
• Pivotal mental states

  2020cites this paper
• 5-HT 2A Receptors and BDNF Regulation: Implications for Psychopathology

  2018cites this paper
• Brain Circuits Regulated by the 5-HT 2A Receptor: Behavioural Consequences on Anxiety and Fear Memory

  2018cites this paper
• Serotonin and brain function: a tale of two receptors

  2017cites this paper
• Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders

  2017cites this paper
• The hallucinogen 2,5-dimethoxy-4-iodoamphetamine hydrochloride activates neurotrophin receptors in a neuronal cell line and promotes neurites extension

  2017cites this paper
• Serotonin regulates brain-derived neurotrophic factor expression in select brain regions during acute psychological stress

  2016cites this paper
• Fluvoxamine moderates reduced voluntary activity following chronic dexamethasone infusion in mice via recovery of BDNF signal cascades.

  2014cites this paper
• Effect of Tenuifoliside A isolated from Polygala tenuifolia on the ERK and PI3K pathways in C6 glioma cells.

  2014cites this paper
• Effect of central administration of the neurotrophic factors BDNF and GDNF on the functional activity and expression of 5-HT2A serotonin receptors in mice genetically predisposed to depressive-like behavior

  2014cites this paper
• Yokukansan, a traditional Japanese herbal medicine, promotes neurite outgrowth in PC12 cells through the activation of extracellular signal regulated kinase 1/2 and phosphatidylinositol 3-kinase/Akt

  2013cites this paper
• The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs.

  2013cites this paper
• 5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway.

  2013cites this paper
• Relations astrocytes-neurones et mécanismes d'action des inhibiteurs sélectifs de recapture de la sérotonine : rôle du BDNF et des récepteurs 5-HT2A

  2013cites this paper
• 5-HT 2 ligands in the treatment of anxiety and depression

  2012cites this paper
• Serotonin: from top to bottom

  2012cites this paper
• A molecular characterization of the choroid plexus and stress-induced gene regulation

  2012cites this paper
• 5-HT2 ligands in the treatment of anxiety and depression

  2012cites this paper
• Gene Regulation by Drugs Used to Treat Mood Disorders

  2011cites this paper
• Current and emerging molecular targets in glioma

  2010cites this paper
• Correction for reported cervical cancer mortality data in Brazil, 1996-2005.

  2010cites this paper
• A role for p11 in the antidepressant action of brain-derived neurotrophic factor.

  2010cites this paper
• Chapter 21 – Multiple Sclerosis and Depression: A Neuroimmunological Perspective

  2010cites this paper
• Genetic variation in brain-derived neurotrophic factor is associated with serotonin transporter but not serotonin-1A receptor availability in men.

  2009cites this paper
• Increased grey matter densities in schizophrenia patients with negative symptoms after treatment with quetiapine: a voxel-based morphometry study

  2009cites this paper
• Progesterone Pretreatment Enhances Serotonin-Stimulated BDNF Gene Expression in Rat C6 Glioma Cells Through Production of 5α-Reduced Neurosteroids

  2008cites this paper
• The molecular neurobiology of depression

  2008cites this paper
• Assessing the Neuronal Serotonergic Target-based Antidepressant Stratagem: Impact of In Vivo Interaction Studies and Knockout Models

  2008cites this paper
• The molecular neurobiology of depression.

  2007cites this paper
• Multiple genes and factors associated with bipolar disorder converge on growth factor and stress activated kinase pathways controlling translation initiation: implications for oligodendrocyte viability.

  2007cites this paper
• Calmodulin Is a 5-HT Receptor-Interacting and Regulatory Protein

  2007cites this paper
• The Neuropeptide VGF Produces Antidepressant-Like Behavioral Effects and Enhances Proliferation in the Hippocampus

  2007cites this paper
• Monoaminergic neuronal activity up-regulates BDNF synthesis in cultured neonatal rat astrocytes.

  2006cites this paper
• Aspects of Growth Hormone and Insulin-Like Growth Factor-I Related to Neuroprotection, Regeneration, and Functional Plasticity in the Adult Brain

  2006cites this paper
• Serotonergic 5-HT2A receptor stimulation induces steroid 5alpha-reductase gene expression in rat C6 glioma cells via transcription factor Egr-1.

  2005cites this paper
• Section V. Serotonin system.

  2005cites this paper
• Novel targets for valproic acid: up‐regulation of melatonin receptors and neurotrophic factors in C6 glioma cells

  2005cites this paper
• Serotonin increases glial cell line-derived neurotrophic factor release in rat C6 glioblastoma cells.

  2004cites this paper
• Nerve growth factor induces elevation of steroid 5alpha-reductase mRNA levels in rat C6 glioma cells through expression of transcription factor Egr-1.

  2004cites this paper
• Recovery of hippocampal cell proliferation and BDNF levels, both of which are reduced by repeated restraint stress, is accelerated by chronic venlafaxine

  2004cites this paper
• New insights into the mechanisms of antidepressant therapy.

  2004cites this paper
• A neural signaling triumvirate that influences ageing and age-related disease: insulin/IGF-1, BDNF and serotonin.

  2004cites this paper
• Prenatal cocaine exposure decreases brain-derived neurotrophic factor proteins in the rat brain.

  2004cites this paper