Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials

Aliment Pharmacol Ther 2011; 34: 808–816

• Publication year

  2011

• Venue

  Alimentary Pharmacology and Therapeutics

• Publication date

  2011-08-02

• Fields of study

  Medicine, Computer Science

• Identifiers
  DOI 10.1111/j.1365-2036.2011.04790.xPMID 21810115PMCID 3201839
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010cited by this paper
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  2009cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2000influential reference
• Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.

  2000cited by this paper
• Misoprostol Reduces Serious Gastrointestinal Complications in Patients with Rheumatoid Arthritis Receiving Nonsteroidal Anti-Inflammatory Drugs

  1995cited by this paper
• Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs.

  1992cited by this paper
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  1983cited by this paper
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  1983cited by this paper

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  2025cites this paper
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  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2015cites this paper
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  2014cites this paper
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