The role of NF-kappaB in 6-hydroxydopamine- and TNFalpha-induced apoptosis of PC12 cells.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Naunyn-Schmiedeberg's Archives of Pharmacology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15141332
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The IKK NF-kappa B system: a treasure trove for drug development.

  2004cited by this paper
• Nuclear translocation of nuclear transcription factor-kappa B by alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors leads to transcription of p53 and cell death in dopaminergic neurons.

  2003cited by this paper
• Parkinsonian Mimetics Induce Aspects of Unfolded Protein Response in Death of Dopaminergic Neurons*

  2003cited by this paper
• Molecular Pathways of Neurodegeneration in Parkinson's Disease

  2003cited by this paper
• Evidence that reactive oxygen species do not mediate NF-kappaB activation.

  2003cited by this paper
• Signalling pathways of the TNF superfamily: a double-edged sword

  2003cited by this paper
• The Caenorhabditis elegans dopaminergic system: opportunities for insights into dopamine transport and neurodegeneration.

  2003cited by this paper
• MPP+ Induces the Endoplasmic Reticulum Stress Response in Rabbit Brain Involving Activation of the ATF‐6 and NF‐κB Signaling Pathways

  2003cited by this paper
• Regulation of Body Temperature and Neuroprotection by Endogenous Interleukin-6 in Cerebral Ischemia

  2003cited by this paper
• Glutamate activates NF-kappaB through calpain in neurons.

  2003cited by this paper
• NF-kappaB at the crossroads of life and death.

  2002cited by this paper
• Opposing roles for NF-kappa B/Rel factors p65 and c-Rel in the modulation of neuron survival elicited by glutamate and interleukin-1beta.

  2002cited by this paper
• Fatal shift of signal transduction is an integral part of neuronal differentiation: JNKs realize TNFalpha-mediated apoptosis in neuronlike, but not naive, PC12 cells.

  2002cited by this paper
• Attenuation of 6-hydroxydopamine (6-OHDA)-induced nuclear factor-kappaB (NF-kappaB) activation and cell death by tea extracts in neuronal cultures.

  2002cited by this paper
• Lack of correlation between NF-kappaB activation and induction of programmed cell death in PC12 pheochromocytoma cells treated with 6-hydroxydopamine or the cannabinoid receptor 1-agonist CP55,940.

  2002cited by this paper
• Prostaglandin A1 inhibits rotenone‐induced apoptosis in SH‐SY5Y cells

  2002cited by this paper
• Endoplasmic Reticulum Stress and the Unfolded Protein Response in Cellular Models of Parkinson's Disease

  2002cited by this paper
• Experimental models of Parkinson's disease

  2001cited by this paper
• Activation of nuclear transcription factor kappa B (NF‐κB) is essential for dopamine‐induced apoptosis in PC12 cells

  2001cited by this paper
• Nuclear factor kappaB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2.

  2001cited by this paper
• 6-hydroxydopamine-induced nuclear factor-kappa B activation in PC12 cells.

  2001cited by this paper
• Nuclear factor-kappaB activation is not involved in a MPTP model of Parkinson's disease.

  2001cited by this paper
• Role of NF-kappaB in p53-mediated programmed cell death.

  2000cited by this paper
• Induction of Interleukin-6 by Depolarization of Neurons

  2000cited by this paper
• The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus.

  2000cited by this paper
• Nerve growth factor inhibits apoptosis induced by tumor necrosis factor in PC12 cells

  1999cited by this paper
• Bradykinin Induces Interleukin‐6 Expression in Astrocytes Through Activation of Nuclear Factor‐κB

  1999cited by this paper
• Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease.

  1997cited by this paper
• NF kappa B-independent transcriptional induction of the human manganous superoxide dismutase gene.

  1997cited by this paper
• Suppression of TNF-alpha-induced apoptosis by NF-kappaB.

  1996cited by this paper
• Manipulation of distinct NFkappaB proteins alters interleukin-1beta-induced human rheumatoid synovial fibroblast prostaglandin E2 formation.

  1996cited by this paper
• Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B.

  1995cited by this paper
• c-Myc and apoptosis.

  1995cited by this paper
• Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

  1995cited by this paper
• Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis.

  1994cited by this paper
• The determination of hydroxydopamines and other trace amines in the urine of Parkinsonian patients and normal controls

  1993cited by this paper
• Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

  1992cited by this paper
• Interaction of an NF-kappa B-like factor with a site upstream of the c-myc promoter.

  1990cited by this paper
• Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor.

  1989cited by this paper
• Mass fragmentography of dopamine and 6-hydroxydopamine. Application to the determination of dopamine in human brain biopsies from the caudate nucleus.

  1974cited by this paper

• The protective effect of parthenolide in an in vitro model of Parkinson’s disease through its regulation of nuclear factor-kappa B and oxidative stress

  2024cites this paper
• New models of Parkinson’s like neuroinflammation in human microglia clone 3: Activation profiles induced by INF-γ plus high glucose and mitochondrial inhibitors

  2022cites this paper
• Modeling Sympathetic Hyperactivity in Alzheimer’s Related Bone Loss

  2021cites this paper
• PPAR-γ agonist pioglitazone reduces microglial proliferation and NF-κB activation in the substantia nigra in the 6-hydroxydopamine model of Parkinson’s disease

  2019cites this paper
• Ivalin Induces Mitochondria-Mediated Apoptosis Associated with the NF-κB Activation in Human Hepatocellular Carcinoma SMMC-7721 Cells

  2019cites this paper
• Dopaminergic Neuroprotection with Ginkgolide in 6-Hydroxydopamine Rat Parkinson’s Disease Model

  2019cites this paper
• Examining the neuroprotective effects of protocatechuic acid and chrysin on in vitro and in vivo models of Parkinson disease.

  2015cites this paper
• Protection by genistein on cortical neurons against oxidative stress injury via inhibition of NF-kappaB, JNK and ERK signaling pathway

  2015cites this paper
• Microglial TNF‐α mediates enhancement of dopaminergic degeneration by brain angiotensin

  2014cites this paper
• A novel tetramethylpyrazine bis-nitrone (TN-2) protects against 6-hydroxyldopamine-induced neurotoxicity via modulation of the NF-κB and the PKCα/PI3-K/Akt pathways.

  2014cites this paper
• Cathepsin X promotes 6-hydroxydopamine-induced apoptosis of PC12 and SH-SY5Y cells.

  2014cites this paper
• Microglial Cells Are Involved in the Susceptibility of NADPH Oxidase Knockout Mice to 6-Hydroxy-Dopamine-Induced Neurodegeneration

  2013cites this paper
• RETRACTED: 6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-κB factors.

  2013cites this paper
• RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells.

  2013cites this paper
• Title Mitochondrial neuronal uncoupling proteins : a target forpotential disease-modification in Parkinson ' s disease

  2012cites this paper
• Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease

  2012cites this paper
• Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease.

  2011cites this paper
• Triptolide Down‐regulates COX‐2 Expression and PGE2 Release by Suppressing the Activity of NF‐κB and MAP kinases in Lipopolysaccharide‐treated PC12 Cells

  2011cites this paper
• Chrysotoxine, a novel bibenzyl compound, inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-κB modulation.

  2010influential citation
• Stem cell marker olfactomedin 4: critical appraisal of its characteristics and role in tumorigenesis

  2010cites this paper
• Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappa B modulation in MES23.5 cells.

  2009cites this paper
• NF-kappaB signaling in cerebral ischemia.

  2009cites this paper
• Influence des agonistes dopaminergiques et des facteurs de transcriptions sur la réponse cellulaire face au stress oxydant

  2008cites this paper
• Bilobalide inhibits 6-OHDA-induced activation of NF-κB and loss of dopaminergic neurons in rat substantia nigra

  2008cites this paper
• Dual roles of NF-κB in cell survival and implications of NF-κB inhibitors in neuroprotective therapy

  2007cites this paper
• Dual roles of NF-kappaB in cell survival and implications of NF-kappaB inhibitors in neuroprotective therapy.

  2007cites this paper
• Apoptotic neuronal death in Parkinson's disease: involvement of nitric oxide.

  2007cites this paper
• NF-kappaB as a potential molecular target for cancer therapy.

  2007cites this paper
• Activation of NFκB and Ub-proteasome pathway during apoptosis induced by a serum factor is mediated through the upregulation of the 26S proteasome subunits

  2006cites this paper
• Award Number: W81XWH-05-1-0580 TITLE: The Identification of Splice Variants as Molecular Markers in Parkinson’s Disease

  2006cites this paper
• Divergent roles of IRE1alpha and PERK in the unfolded protein response.

  2006cites this paper
• Bim and Noxa Are Candidates to Mediate the Deleterious Effect of the NF-κB Subunit RelA in Cerebral Ischemia

  2006cites this paper
• The Role of Oxidative Stress in the Dysregulation of Gene Expression and Protein Metabolism in Neurodegenerative Disease

  2006cites this paper
• Pro-apoptotic role of NF-kappaB: implications for cancer therapy.

  2006cites this paper
• A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools

  2005cites this paper