Mycobacterium avium MAV_2941 mimics phosphoinositol-3-kinase to interfere with macrophage phagosome maturation.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Microbes and infection

• Publication date

  2015-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.micinf.2015.05.005PMID 26043821PMCID PMC4554883
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of Mycobacterium avium genes expressed during in vivo infection and the role of the oligopeptide transporter OppA in virulence.

  2014cited by this paper
• Class III phosphatidylinositol 3–kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic

  2013cited by this paper
• Mutation in Archain 1, a Subunit of COPI Coatomer Complex, Causes Diluted Coat Color and Purkinje Cell Degeneration

  2010influential reference
• The phosphoinositide phosphatase SopB manipulates membrane surface charge and trafficking of the Salmonella-containing vacuole.

  2010cited by this paper
• Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria

  2009cited by this paper
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  2009cited by this paper
• Sorting of the v-SNARE VAMP7 in Dictyostelium discoideum: a role for more than one Adaptor Protein (AP) complex.

  2008cited by this paper
• SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34

  2008cited by this paper
• Protein networks supporting AP-3 function in targeting lysosomal membrane proteins.

  2008cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

  2005cited by this paper
• Identification of Mycobacterium avium genes up-regulated in cultured macrophages and in mice.

  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
• Modulation of cellular function by TAT mediated transduction of full length proteins.

  2003cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Interaction of Mycobacterium avium with environmental amoebae enhances virulence

  1997cited by this paper
• [Mycobacterium avium complex].

  1995cited by this paper
• Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase.

  1994cited by this paper
• The Mycobacterium avium complex

  1993cited by this paper
• Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic

  1991cited by this paper
• Interaction of Mycobacterium avium complex with human macrophages: roles of membrane receptors and serum proteins

  1991cited by this paper

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• Phenothiazines boost host control of Mycobacterium avium infection in primary human macrophages.

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  2021influential citation
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