Assessment of Factors Regulating Axon Growth between the Cortex and Spinal Cord in Organotypic Co-Cultures: Effects of Age and Neurotrophic Factors

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of Neurotrauma

• Publication date

  2004-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/089771504322972121PMID 15115608
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• The origin of corticospinal projection neurons in rat

  2004cited by this paper
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  2004cited by this paper
• Lack of enhanced spinal regeneration in Nogo-deficient mice.

  2003cited by this paper
• Axon regeneration in young adult mice lacking Nogo-A/B.

  2003cited by this paper
• Systemic deletion of the myelin-associated outgrowth inhibitor Nogo-A improves regenerative and plastic responses after spinal cord injury.

  2003cited by this paper
• Chondroitinase ABC promotes functional recovery after spinal cord injury

  2002cited by this paper
• NG2 Is a Major Chondroitin Sulfate Proteoglycan Produced after Spinal Cord Injury and Is Expressed by Macrophages and Oligodendrocyte Progenitors

  2002cited by this paper
• Retrograde Repression of Growth-Associated Protein-43 mRNA Expression in Rat Cortical Neurons

  2002cited by this paper
• Neurotrophic Factors and Receptors in the Immature and Adult Spinal Cord after Mechanical Injury or Kainic Acid

  2001cited by this paper
• Soluble myelin-associated glycoprotein released from damaged white matter inhibits axonal regeneration.

  2001cited by this paper
• Locomotor Recovery in Spinal Cord-Injured Rats Treated with an Antibody Neutralizing the Myelin-Associated Neurite Growth Inhibitor Nogo-A

  2001cited by this paper
• Regeneration of Lesioned Corticospinal Tract Fibers in the Adult Rat Induced by a Recombinant, Humanized IN-1 Antibody Fragment

  2000cited by this paper
• Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1

  2000influential reference
• Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation.

  1999cited by this paper
• A rapid method for semi-quantitative analysis of neurite outgrowth from chick DRG explants using image analysis.

  1999cited by this paper
• Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism.

  1999cited by this paper
• Transplants of Fibroblasts Genetically Modified to Express BDNF Promote Regeneration of Adult Rat Rubrospinal Axons and Recovery of Forelimb Function

  1999cited by this paper
• Degradation of chondroitin sulfate proteoglycan enhances the neurite-promoting potential of spinal cord tissue.

  1998cited by this paper
• Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions

  1998cited by this paper
• Collagen containing neurotrophin-3 (NT-3) attracts regrowing injured corticospinal axons in the adult rat spinal cord and promotes partial functional recovery.

  1998cited by this paper
• Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord

  1998cited by this paper
• Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions

  1998cited by this paper
• Regeneration of adult axons in white matter tracts of the central nervous system

  1997cited by this paper
• Cellular Delivery of Neurotrophin-3 Promotes Corticospinal Axonal Growth and Partial Functional Recovery after Spinal Cord Injury

  1997influential reference
• BDNF and NT-4/5 Prevent Atrophy of Rat Rubrospinal Neurons after Cervical Axotomy, Stimulate GAP-43 and Tα1-Tubulin mRNA Expression, and Promote Axonal Regeneration

  1997cited by this paper
• Treatment of the chronically injured spinal cord with neurotrophic factors can promote axonal regeneration from supraspinal neurons.

  1997cited by this paper
• GAP-43: an intrinsic determinant of neuronal development and plasticity.

  1997cited by this paper
• Effects of systemic administration of 2-(4-phenyl-piperidino)-cyclohexanol (vesamicol) and an organophosphate DDVP on the cholinergic system in brain regions of rats.

  1997cited by this paper
• B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system

  1997cited by this paper
• The muddle with MAG.

  1996cited by this paper
• The Muddle with MAG

  1996cited by this paper
• Spinal Cord Repair in Adult Paraplegic Rats: Partial Restoration of Hind Limb Function

  1996cited by this paper
• Nerve growth factor promotes regeneration of sensory axons into adult rat spinal cord.

  1996cited by this paper
• Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice.

  1995cited by this paper
• Recovery from spinal cord injury mediated by antibodies to neurite growth inhibitors

  1995cited by this paper
• A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

  1995cited by this paper
• Intrinsic changes in developing retinal neurons result in regenerative failure of their axons.

  1995cited by this paper
• Fibroblasts genetically modified to produce nerve growth factor induce robust neuritic ingrowth after grafting to the spinal cord.

  1994cited by this paper
• Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth.

  1994cited by this paper
• Response of rubrospinal and corticospinal neurons to injury and neurotrophins.

  1994cited by this paper
• Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

  1994cited by this paper
• A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration.

  1994cited by this paper
• Sprouting and Regeneration of Lesioned Corticospinal Tract Fibres in the Adult Rat Spinal Cord

  1993cited by this paper
• Characterization of a Neurite Outgrowth Inhibitor Expressed After CNS Injury

  1993cited by this paper
• Spontaneous morphological changes by overexpression of the growth-associated protein B-50/GAP-43 in a PC12 cell line.

  1993cited by this paper
• Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones

  1993cited by this paper
• Inhibitors of neurite growth.

  1993cited by this paper
• Neuronal colocalization of mRNAs for neurotrophins and their receptors in the developing central nervous system suggests a potential for autocrine interactions.

  1993cited by this paper
• GAP-43 as a modulator of G protein transduction in the growth cone.

  1992cited by this paper
• Suppression of the onset of myelination extends the permissive period for the functional repair of embryonic spinal cord.

  1992cited by this paper
• Neurotrophin receptors: a window into neuronal differentiation.

  1992cited by this paper
• Recovery of function after spinal cord hemisection in newborn and adult rats: differential effects on reflex and locomotor function.

  1992cited by this paper
• Accelerated Differentiation in Response to Retinoic Acid After Retrovirally Mediated Gene Transfer of GAP‐43 into Mouse Neuroblastoma Cells

  1992cited by this paper
• The development of the corticospinal projection.

  1992cited by this paper
• Inhibition of nerve growth factor-induced B-50/GAP-43 expression by antisense oligomers interferes with neurite outgrowth of PC12 cells.

  1992cited by this paper
• Transient and persistent expression of NT-3/HDNF mRNA in the rat brain during postnatal development

  1991cited by this paper
• Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43

  1991cited by this paper
• Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with the expression of inhibitory molecules on reactive astrocytes

  1991cited by this paper
• Expression of the growth-associated protein GAP-43 in adult rat retinal ganglion cells following axon injury.

  1991cited by this paper
• Regional expression of the nerve growth factor gene family in rat brain during development.

  1991cited by this paper
• Inhibition of neurite outgrowth on astroglial scars in vitro

  1990cited by this paper
• Transfection of PC12 cells with the human GAP-43 gene: effects on neurite outgrowth and regeneration.

  1990cited by this paper
• Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors

  1990cited by this paper
• NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression.

  1990cited by this paper
• Axonal growth-associated proteins.

  1989cited by this paper
• Antibody against myelin-associated inhibitor of neurite growth neutralizes nonpermissive substrate properties of CNS white matter.

  1988cited by this paper
• An immunohistochemical study of the nerve growth factor receptor in developing rats

  1988cited by this paper
• Differential expression of the nerve growth factor receptor gene in multiple brain areas.

  1988cited by this paper
• Effect of prenatal exposure to alcohol on the distribution and time of origin of corticospinal neurons in the rat

  1987cited by this paper
• Mouse nerve growth factor gene: structure and expression

  1987influential reference
• Growth and target finding by axons of the corticospinal tract in prenatal and postnatal rats.

  1982cited by this paper
• Organotypic monolayer cultures of nervous tissue.

  1981cited by this paper
• Cell migrations to the isocortex in the rat

  1968cited by this paper
• The migration of neuroblasts in the developing cerebral cortex.

  1965cited by this paper

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  2019cites this paper
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  2015cites this paper
• Propriospinal interneurons in the spotlight for anatomical and functional recovery after spinal cord injury

  2015cites this paper
• Studying Axonal Outgrowth and Regeneration of the Corticospinal Tract in Organotypic Slice Cultures

  2015influential citation
• Organotypic slice co-culture systems to study axon regeneration in the dopaminergic system ex vivo.

  2014cites this paper
• Primary olfactory mucosal cells promote axonal outgrowth in a three‐dimensional assay

  2014cites this paper
• Regioselective Biolistic Targeting in Organotypic Brain Slices Using a Modified Gene Gun

  2014cites this paper
• Optimized heterologous transfection of viable adult organotypic brain slices using an enhanced gene gun

  2013cites this paper
• Design, Fabrication and Optimization of Microfluidic Chambers for Neurobiology Research

  2013cites this paper
• Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells

  2012cites this paper
• Human platelet-rich plasma promotes axon growth in brain–spinal cord coculture

  2012cites this paper
• KLF 9 in Purkinje cells

  2012cites this paper
• A new three-dimensional axonal outgrowth assay for central nervous system regeneration.

  2011cites this paper
• An in vitro model of adult mammalian nerve repair.

  2010cites this paper
• The effects of combining chondroitinase ABC and NEP1-40 on the corticospinal axon growth in organotypic co-cultures.

  2010cites this paper
• CD133+ cells from human umbilical cord blood reduce cortical damage and promote axonal growth in neonatal rat organ co‐cultures exposed to hypoxia

  2010influential citation
• ulturing thick brain slices : An interstitial 3 D microperfusion system for nhanced viability

  2009cites this paper
• Chondroitinase ABC promotes corticospinal axon growth in organotypic cocultures

  2009cites this paper
• Cocultures of Rat Sensorimotor Cortex and Spinal Cord Slices to Investigate Corticospinal Tract Sprouting

  2009cites this paper
• Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS.

  2009cites this paper
• CD133+ cells from human peripheral blood promote corticospinal axon regeneration

  2008cites this paper
• BDNF, NT-3, and NGF Released From Transplanted Neural Progenitor Cells Promote Corticospinal Axon Growth in Organotypic Cocultures

  2007cites this paper
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  2007cites this paper
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  2007cites this paper
• Brain slices as models for neurodegenerative disease and screening platforms to identify novel therapeutics.

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• Thick brain slice cultures and a custom-fabricated multiphoton imaging system: progress towards development of a 3D hybrot model

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• Preparation of organotypic hippocampal slice cultures: interface method

  2006cites this paper
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  2006cites this paper
• Differential effects of forskolin on tyrosine hydroxylase gene transcription in identified brainstem catecholaminergic neuronal subtypes in organotypic culture

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