The classical srb4-138 mutant allele causes dissociation of yeast Mediator.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2006-10-27

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BBRC.2006.08.099PMID 16962561
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mediator as a General Transcription Factor*

  2006cited by this paper
• Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions.

  2006cited by this paper
• Head module control of mediator interactions.

  2006cited by this paper
• Mediator and the mechanism of transcriptional activation.

  2005cited by this paper
• Genome wide analysis of nucleosome density histone acetylation and HDAC function in fission yeast

  2005cited by this paper
• The yeast Mediator complex and its regulation.

  2005cited by this paper
• The Structural and Functional Role of Med5 in the Yeast Mediator Tail Module*

  2005cited by this paper
• A Conserved Mediator Hinge Revealed in the Structure of the MED7·MED21 (Med7·Srb7) Heterodimer*

  2005cited by this paper
• A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.

  2004cited by this paper
• A high resolution protein interaction map of the yeast Mediator complex.

  2004cited by this paper
• The Soh1/MED31 Protein Is an Ancient Component of Schizosaccharomyces pombe and Saccharomyces cerevisiae Mediator*

  2004cited by this paper
• TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution

  2003cited by this paper
• Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method.

  2002cited by this paper
• A Complex of the Srb8, -9, -10, and -11 Transcriptional Regulatory Proteins from Yeast*

  2002cited by this paper
• Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction.

  2002cited by this paper
• The Structural and Functional Organization of the Yeast Mediator Complex*

  2001cited by this paper
• The tandem affinity purification (TAP) method: a general procedure of protein complex purification.

  2001cited by this paper
• Vectors and gene targeting modules for tandem affinity purification in Schizosaccharomyces pombe

  2001cited by this paper
• Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification.

  2000cited by this paper
• Structural organization of yeast and mammalian mediator complexes.

  2000cited by this paper
• Purification and Characterization of RNA Polymerase II Holoenzyme from Schizosaccharomyces pombe *

  2000cited by this paper
• Mediator protein mutations that selectively abolish activated transcription.

  1999cited by this paper
• Conserved structures of mediator and RNA polymerase II holoenzyme.

  1999cited by this paper
• A generic protein purification method for protein complex characterization and proteome exploration

  1999cited by this paper
• Requirement for a Functional Interaction between Mediator Components Med6 and Srb4 in RNA Polymerase II Transcription

  1998cited by this paper
• Interplay of Positive and Negative Regulators in Transcription Initiation by RNA Polymerase II Holoenzyme

  1998cited by this paper
• The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain.

  1998cited by this paper
• Identification of New Mediator Subunits in the RNA Polymerase II Holoenzyme from Saccharomyces cerevisiae *

  1998cited by this paper
• Transcriptional activation independent of TFIIH kinase and the RNA polymerase II mediator in vivo

  1998cited by this paper
• An activator target in the RNA polymerase II holoenzyme.

  1998cited by this paper
• Dissecting the regulatory circuitry of a eukaryotic genome.

  1998cited by this paper
• Identification of Rox3 as a Component of Mediator and RNA Polymerase II Holoenzyme*

  1997cited by this paper
• Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.

  1995cited by this paper
• A kinase–cyclin pair in the RNA polymerase II holoenzyme

  1995cited by this paper
• General requirement for RNA polymerase II holoenzymes in vivo.

  1995cited by this paper
• A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II.

  1994cited by this paper
• A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast.

  1993cited by this paper
• A mediator required for activation of RNA polymerase II transcription in vitro

  1991cited by this paper
• Resolution of factors required for the initiation of transcription by yeast RNA polymerase II.

  1990cited by this paper
• A novel mediator between activator proteins and the RNA polymerase II transcription apparatus.

  1990cited by this paper
• THE PHYSIOLOGICAL RELATION OF PLANT CAROTINOIDS TO THE CAROTINOIDS OF THE COW, HORSE, SHEEP, GOAT, PIG, AND HEN

  1916cited by this paper

• Unique Role of Med8 in Ace2 Recruitment and Target Gene Expression in Schizosaccharomyces pombe

  2025cites this paper
• Genomic analysis of Rad26 and Rad1–Rad10 reveals differences in their dependence on Mediator and RNA polymerase II

  2022cites this paper
• Genome-wide distribution of Rad26 and Rad1-Rad10 reveals their relationship with Mediator and RNA polymerase II

  2021cites this paper
• Architectural Mediator subunits are differentially essential for global transcription in Saccharomyces cerevisiae.

  2021cites this paper
• Architectural Mediator subunits are differentially essential for global transcription in yeast

  2020cites this paper
• A comprehensive analysis of Med12 controlled (l)ncRNAs and characterization of a novel Sall1 antisense transcript

  2020cites this paper
• Mediator, known as a coactivator, can act in transcription initiation in an activator-independent manner in vivo.

  2018cites this paper
• The mediator complex in genomic and non‐genomic signaling in cancer

  2017cites this paper
• Evidence that Mediator is essential for Pol II transcription, but is not a required component of the preinitiation complex in vivo

  2017cites this paper
• Emerging functions of multi-protein complex Mediator with special emphasis on plants

  2017cites this paper
• Cdk9 and Brd4 regulate eukaryotic transcription

  2017cites this paper
• Transcriptional Regulation of Clr-b (Clec2d) in Health and Disease

  2017cites this paper
• Mediator and NER factors in transcription initiation

  2017influential citation
• Core Mediator structure at 3.4 Å extends model of transcription initiation complex

  2017cites this paper
• Mediator Architecture and RNA Polymerase II Interaction.

  2016cites this paper
• Mediator Undergoes a Compositional Change during Transcriptional Activation.

  2016cites this paper
• Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries

  2015cites this paper
• Mediator independently orchestrates multiple steps of preinitiation complex assembly in vivo

  2015cites this paper
• Integrative structural and functional studies of Mediator and RNA polymerase II transcription initiation assemblies

  2015cites this paper
• Architecture of the RNA polymerase II–Mediator core initiation complex

  2015cites this paper
• Subunit architecture and functional modular rearrangements of the transcriptional mediator complex.

  2014cites this paper
• Redefining the modular organization of the core Mediator complex

  2014cites this paper
• Genome-Wide Association of Mediator and RNA Polymerase II in Wild-Type and Mediator Mutant Yeast

  2014cites this paper
• The Metazoan-Specific Mediator Subunit 26 (Med26) Is Essential for Viability and Is Found at both Active Genes and Pericentric Heterochromatin in Drosophila melanogaster

  2014cites this paper
• Med12 is an essential coordinator of gene regulation during mouse development

  2011cites this paper
• Preparation and topology of the Mediator middle module

  2010cites this paper
• Structure and functional architecture of the Mediator middle module from budding yeast.

  2010cites this paper
• MED14 Tethers Mediator to the N-Terminal Domain of Peroxisome Proliferator-Activated Receptor γ and Is Required for Full Transcriptional Activity and Adipogenesis

  2010cites this paper
• [The functional interaction of an RNA polymerase II Rpb11 subunit with the Med18 subunit (Srb5) of the Saccharomyces cerevisiae mediator complex].

  2009cites this paper
• Mediator complex association with constitutively transcribed genes in yeast

  2009cites this paper
• Functional interaction of the RNA polymerase II Rpb11 subunit with the subunit Med18 (Srb5) of the Saccharomyces cerevisiae mediator complex

  2009cites this paper
• Two Modes of Transcriptional Activation at Native Promoters by NF-κB p65

  2009cites this paper
• Snf1‐independent, glucose‐resistant transcription of Adr1‐dependent genes in a mediator mutant of Saccharomyces cerevisiae

  2009cites this paper
• The Transcriptional Coactivators SAGA, SWI/SNF, and Mediator Make Distinct Contributions to Activation of Glucose-repressed Genes*

  2008cites this paper
• Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways

  2008cites this paper
• Mediator Requirement Downstream of Chromatin Remodeling during Transcriptional Activation of CHA1 in Yeast*

  2008cites this paper
• Transcriptional regulation of the sodium-coupled neutral amino acid transporter (SNAT2) gene by amino acid availability

  2008cites this paper
• Med19(Rox3) Regulates Intermodule Interactions in the Saccharomyces cerevisiae Mediator Complex*

  2007cites this paper
• Current awareness on yeast

  2007cites this paper