Thermolysin damages animal life through degradation of plasma proteins enhanced by rapid cleavage of serpins and activation of proteases.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Archives of Insect Biochemistry and Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1002/arch.21178PMID 25042057
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Drosophila melanogaster prophenoloxidases respond inconsistently to Cu2+ and have different activity in vitro.

  2012cited by this paper
• Hindgut Innate Immunity and Regulation of Fecal Microbiota through Melanization in Insects*

  2012cited by this paper
• Genetic evidence of a redox‐dependent systemic wound response via Hayan Protease‐Phenoloxidase system in Drosophila

  2012cited by this paper
• Bacillus anthracis protease InhA regulates BslA‐mediated adhesion in human endothelial cells

  2012cited by this paper
• Existence of Prophenoloxidase in Wing Discs: A Source of Plasma Prophenoloxidase in the Silkworm, Bombyx mori

  2012cited by this paper
• Properties of Drosophila melanogaster prophenoloxidases expressed in Escherichia coli.

  2012cited by this paper
• Extracellular metalloproteases from bacteria

  2011cited by this paper
• Genome Sequencing and Comparative Transcriptomics of the Model Entomopathogenic Fungi Metarhizium anisopliae and M. acridum

  2011cited by this paper
• Bacillus anthracis Protease InhA Increases Blood-Brain Barrier Permeability and Contributes to Cerebral Hemorrhages

  2011cited by this paper
• Characterization of a regulatory unit that controls melanization and affects longevity of mosquitoes

  2011cited by this paper
• InhA1, NprA, and HlyII as Candidates for Markers To Differentiate Pathogenic from Nonpathogenic Bacillus cereus Strains

  2010cited by this paper
• Coagulation Systems of Invertebrates and Vertebrates and Their Roles in Innate Immunity: The Same Side of Two Coins?

  2010cited by this paper
• Distinct melanization pathways in the mosquito Aedes aegypti.

  2010cited by this paper
• Protease inhibitors and proteolytic signalling cascades in insects.

  2010cited by this paper
• Mosquito immunity.

  2010cited by this paper
• Comparative analysis of the virulence of invertebrate and mammalian pathogenic bacteria in the oral insect infection model Galleria mellonella.

  2010cited by this paper
• Immunity in lepidopteran insects.

  2010cited by this paper
• Coevolution between pathogen-derived proteinases and proteinase inhibitors of host insects

  2010cited by this paper
• A comparative analysis of serpin genes in the silkworm genome.

  2009cited by this paper
• Identification of the gene encoding pro‐phenoloxidase A3 in the fruitfly, Drosophila melanogaster

  2009cited by this paper
• The InhA Metalloproteases of Bacillus cereus Contribute Concomitantly to Virulence

  2009cited by this paper
• The Thermolysin Family (M4) of Enzymes: Therapeutic and Biotechnological Potential

  2009cited by this paper
• Corruption of Innate Immunity by Bacterial Proteases

  2008cited by this paper
• 4 – PHENOLOXIDASES IN INSECT IMMUNITY

  2008cited by this paper
• The proPO-system: pros and cons for its role in invertebrate immunity.

  2008cited by this paper
• Engineering, expression, purification, and production of recombinant thermolysin.

  2007cited by this paper
• Microbial Metalloproteinases Mediate Sensing of Invading Pathogens and Activate Innate Immune Responses in the Lepidopteran Model Host Galleria mellonella

  2006cited by this paper
• Two Proteases Defining a Melanization Cascade in the Immune System of Drosophila*

  2006cited by this paper
• Secreted Neutral Metalloproteases of Bacillus anthracis as Candidate Pathogenic Factors*

  2006cited by this paper
• Melanogenesis and associated cytotoxic reactions: applications to insect innate immunity.

  2005cited by this paper
• β-1,3-Glucan recognition protein-2 (βGRP-2) from Manduca sexta: an acute-phase protein that binds β-1,3-glucan and lipoteichoic acid to aggregate fungi and bacteria and stimulate prophenoloxidase activation

  2004cited by this paper
• Beta-1,3-glucan recognition protein-2 (betaGRP-2)from Manduca sexta; an acute-phase protein that binds beta-1,3-glucan and lipoteichoic acid to aggregate fungi and bacteria and stimulate prophenoloxidase activation.

  2004cited by this paper
• Manduca sexta Serpin-3 Regulates Prophenoloxidase Activation in Response to Infection by Inhibiting Prophenoloxidase-activating Proteinases*

  2003cited by this paper
• Comparative Trajectories of Active and S195A Inactive Trypsin upon Binding to Serpins*

  2002cited by this paper
• Fluorescent dyes for cell viability: an application on prefixed conditions

  2001cited by this paper
• Recognition and regulation of metalloproteinase activity in the haemolymph of Galleria mellonella: a new pathway mediating induction of humoral immune responses.

  2000cited by this paper
• Purification and characterization of an inducible metalloprotease inhibitor from the hemolymph of greater wax moth larvae, Galleria mellonella.

  1998cited by this paper
• Bacterial extracellular zinc-containing metalloproteases.

  1993cited by this paper
• A fluorimetric study of the role of calcium ions in the stability of thermolysin.

  1977cited by this paper
• Malignant hyperpyrexia.

  1977cited by this paper
• Activation of prephenoloxidase

  1970cited by this paper
• Activation of prephenoloxidase. II. Activation by alpha-chymotrypsin.

  1970cited by this paper
• A modified spectrophotometric determination of chymotrypsin, trypsin, and thrombin.

  1959cited by this paper
• The activation of chymotrypsinogen; isolation and identification of a peptide liberated during activation.

  1955cited by this paper

• Advances in the Novel Functions of Insect Prophenoloxidase.

  2025cites this paper
• Protease S of entomopathogenic bacterium Photorhabdus laumondii: expression, purification and effect on greater wax moth Galleria mellonella

  2024cites this paper
• Comparative Genomics Reveal the Animal-Associated Features of the Acanthopleuribacteraceae Bacteria, and Description of Sulfidibacter corallicola gen. nov., sp., nov.

  2022cites this paper
• The biological role of peroxiredoxins in innate immune responses of aquatic invertebrates

  2019cites this paper
• Immune responses to bacterial and fungal infections in the silkworm, Bombyx mori

  2017cites this paper