UM-Chor1: establishment and characterization of the first validated clival chordoma cell line.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Neurosurgery

• Publication date

  2017-04-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3171/2016.10.JNS16877PMID 28430034PMCID PMC5650943
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Novel method of cell line establishment utilizing fluorescence‐activated cell sorting resulting in 6 new head and neck squamous cell carcinoma lines

  2016cited by this paper
• Prognostic and Therapeutic Markers in Chordomas: A Study of 287 Tumors

  2016cited by this paper
• Brachyury: A Diagnostic Marker for the Differential Diagnosis of Chordoma and Hemangioblastoma versus Neoplastic Histological Mimickers

  2014cited by this paper
• Early-onset colorectal cancer patients without family history are “at very low risk” for lynch syndrome

  2014cited by this paper
• Characterization of T gene sequence variants and germline duplications in familial and sporadic chordoma

  2014cited by this paper
• Generation of a patient-derived chordoma xenograft and characterization of the phosphoproteome in a recurrent chordoma.

  2014cited by this paper
• Overexpression of brachyury contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma

  2014cited by this paper
• Development of transplantable human chordoma xenograft for preclinical assessment of novel therapeutic strategies.

  2014cited by this paper
• Insights into the Hallmarks of Human Nucleus Pulposus Cells with Particular Reference to Cell Viability, Phagocytic Potential and Long Process Formation

  2013cited by this paper
• New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patients

  2013cited by this paper
• A Novel Chordoma Xenograft Allows In Vivo Drug Testing and Reveals the Importance of NF-κB Signaling in Chordoma Biology

  2013cited by this paper
• Mechanisms of chemoresistance in cancer stem cells

  2013cited by this paper
• Characterization of cancer stem-like cells in chordoma

  2012cited by this paper
• Aldehyde Dehydrogenase 1, a Potential Marker for Cancer Stem Cells in Human Sarcoma

  2012cited by this paper
• Characterization of cancer stem-like cells in chordoma.

  2012cited by this paper
• Cancer stem cells and drug resistance: the potential of nanomedicine.

  2012cited by this paper
• Generation of chordoma cell line JHC7 and the identification of Brachyury as a novel molecular target.

  2011cited by this paper
• Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional‐based study

  2011cited by this paper
• Overexpression of Cathepsin Z Contributes to Tumor Metastasis by Inducing Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma

  2011cited by this paper
• In vitro characterization of cells derived from chordoma cell line U-CH1 following treatment with X-rays, heavy ions and chemotherapeutic drugs

  2011cited by this paper
• Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1.

  2011cited by this paper
• Chordoma: clinical characteristics, management and prognosis of a case series of 25 patients

  2010cited by this paper
• CD24: from A to Z

  2010cited by this paper
• Molecular Characterization of Putative Chordoma Cell Lines

  2010cited by this paper
• Single‐marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase

  2010cited by this paper
• Revisiting chordoma with brachyury, a "new age" marker: analysis of a validation study on 51 cases.

  2010cited by this paper
• Changes in neuronal activation patterns in response to androgen deprivation therapy: a pilot study

  2010cited by this paper
• CD24 overexpression in cancer development and progression: a meta-analysis.

  2009cited by this paper
• T (brachyury) gene duplication confers major susceptibility to familial chordoma

  2009cited by this paper
• Enhanced CD24 expression in endometrial carcinoma and its expression pattern in normal and hyperplastic endometrium.

  2009cited by this paper
• Overexpression of CD24, c-myc and Phospholipase 2A in Prostate Cancer Tissue Samples Obtained by Needle Biopsy

  2009cited by this paper
• CD24 Expression Is a Novel Prognostic Factor in Esophageal Squamous Cell Carcinoma

  2009cited by this paper
• Immunohistochemical Comparison of Chordoma With Chondrosarcoma, Myxopapillary Ependymoma, and Chordoid Meningioma

  2009cited by this paper
• The novel oncogene CD24 and its arising role in the carcinogenesis of the GI tract: from research to therapy

  2008cited by this paper
• Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis

  2008cited by this paper
• Cancer Statistics, 2007

  2007cited by this paper
• Chordoma: the nonsarcoma primary bone tumor.

  2007cited by this paper
• ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome.

  2007cited by this paper
• Sacral chordomas: Impact of high-dose proton/photon-beam radiation therapy combined with or without surgery for primary versus recurrent tumor.

  2006cited by this paper
• CD24 is expressed specifically in the nucleus pulposus of intervertebral discs.

  2005cited by this paper
• N-glycosylation patterns of HSA/CD24 from different cell lines and brain homogenates: a comparison.

  2003cited by this paper
• Immunohistochemical analysis of E-cadherin, α-catenin, β-catenin, γ-catenin, and neural cell adhesion molecule (NCAM) in chordoma

  2001cited by this paper
• Immunohistochemical analysis of E-cadherin, alpha-catenin, beta-catenin, gamma-catenin, and neural cell adhesion molecule (NCAM) in chordoma.

  2001cited by this paper
• Prognostic factors in chordoma of the sacrum and mobile spine

  2000cited by this paper
• Proliferative characteristics of fibroblast lines derived from open lung biopsy specimens of patients with IPF (UIP).

  1992cited by this paper

• Pansarcoma Analysis of Cyclin-Dependent Kinase and Cyclin Outlier Gene Expression Highlights CDK7 as a Potential Therapeutic Target in Chordoma.

  2025cites this paper
• Surgical management of skull base and spinal chordomas: A case series with comprehensive review of the literature

  2024cites this paper
• Animal model considerations for chordoma research: reproducing the tumor microenvironment in vivo with humanized mice

  2024cites this paper
• Impact of silencing eEF2K expression on the malignant properties of chordoma

  2023influential citation
• Treatment of Clival Chordomas: A 20-Year Experience and Systematic Literature Review

  2023cites this paper
• Chordoma: demographics and survival analysis with a focus on racial disparities and the role of surgery, a U.S. population-based study

  2023cites this paper
• Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1-Mutated Human Chordoma Xenograft

  2022cites this paper
• Inducing substances for chondrogenic differentiation of dental pulp stem cells in the conditioned medium of a novel chordoma cell line

  2022cites this paper
• Advances in the development of chordoma models for drug discovery and precision medicine.

  2022cites this paper
• A chronicle review of new techniques that facilitate the understanding and development of optimal individualized therapeutic strategies for chordoma

  2022cites this paper
• Combinatorial Natural Killer Cell–based Immunotherapy Approaches Selectively Target Chordoma Cancer Stem Cells

  2021cites this paper
• Aldehyde Dehydrogenase, a Therapeutic Target in Chordoma: Analysis in 3D Cellular Models

  2021cites this paper
• Computational Drug Repositioning Identifies Potentially Active Therapies for Chordoma.

  2020cites this paper
• natural growth dynamics of untreated skull base chordomas in vivo.

  2020cites this paper
• Advancement of PI3 Kinase Inhibitor Combination Therapies for PI3K-Aberrant Chordoma

  2020cites this paper
• Combination of PARP inhibitor and temozolomide to suppress chordoma progression

  2019cites this paper
• MRI-based tumour control probability in skull-base chordomas treated with carbon-ion therapy.

  2019cites this paper
• Characterization of a Clival Chordoma Xenograft Model Reveals Tumor Genomic Instability.

  2018cites this paper
• AHNAK the Giant Protein: Expression, Localization and Functionality in Human Chordoma Cell Lines

  2018cites this paper
• Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury

  2017cites this paper