Inhibition of autologous rosette formation by monoclonal antibody to the sheep erythrocyte receptor.

The commercial monoclonal HuLyT-3, and which recognizes a 55,000-dalton polypeptide associated with the receptor for SRBC on human T lymphocytes, was capable of blocking rosette formation between human T cells and autologous human RBC. Lysostripping of the T cell surface with HuLyT-3 abolished rosette formation with both sheep and autologous RBC. The data suggest that a common structure is involved in the spontaneous rosetting of both sheep and human RBC by human T cells.

• Publication year

  1982

• Venue

  Journal of Immunology

• Publication date

  1982-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.128.4.1930PMID 7061854
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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