The association of type 2 diabetes and insulin resistance/secretion with persistent organic pollutants in two First Nations communities in northern Ontario.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Diabetes & Metabolism

• Publication date

  2013-12-01

• Fields of study

  Biology, Medicine, Geography, Environmental Science

• Identifiers
  DOI 10.1016/j.diabet.2013.01.006PMID 23639570
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Simultaneous exposure of non-diabetics to high levels of dioxins and mercury increases their risk of insulin resistance.

  2011cited by this paper
• Low Dose Organochlorine Pesticides and Polychlorinated Biphenyls Predict Obesity, Dyslipidemia, and Insulin Resistance among People Free of Diabetes

  2011cited by this paper
• Marine Food Pollutants as a Risk Factor for Hypoinsulinemia and Type 2 Diabetes

  2011cited by this paper
• Obesity and Type 2 Diabetes Prevalence in Adults from Two Remote First Nations Communities in Northwestern Ontario, Canada

  2011influential reference
• Obesity and type 2 diabetes in Northern Canada's remote First Nations communities: the dietary dilemma

  2010cited by this paper
• Strong associations between low-dose organochlorine pesticides and type 2 diabetes in Korea.

  2010cited by this paper
• Persistent Organic Pollutant Exposure Leads to Insulin Resistance Syndrome

  2009cited by this paper
• Prevalence of diabetes and body burdens of polychlorinated biphenyls, polybrominated diphenyl ethers, and p,p'-diphenyldichloroethene in Great Lakes sport fish consumers.

  2009cited by this paper
• Obesity and the eating habits of the Aboriginal population.

  2008cited by this paper
• Negative association between plasma levels of adiponectin and polychlorinated biphenyl 153 in obese women under non-energy-restrictive regime

  2008cited by this paper
• A cross-sectional study of the association between persistent organic pollutants and glucose intolerance among Greenland Inuit

  2008cited by this paper
• Polychlorinated Biphenyl-77 Induces Adipocyte Differentiation and Proinflammatory Adipokines and Promotes Obesity and Atherosclerosis

  2008cited by this paper
• Obesity and Physical Activity Among Aboriginal Canadians

  2008cited by this paper
• Association of Brominated Flame Retardants With Diabetes and Metabolic Syndrome in the U.S. Population, 2003–2004

  2008cited by this paper
• Associations between insulin resistance and TNF-alpha in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes.

  2007cited by this paper
• Diabetes in Relation to Serum Levels of Polychlorinated Biphenyls and Chlorinated Pesticides in Adult Native Americans

  2007cited by this paper
• Exposure to persistent organochlorine pollutants and type 2 diabetes mellitus

  2007cited by this paper
• Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome

  2007cited by this paper
• Associations between insulin resistance and TNF-α in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes

  2007cited by this paper
• Association Between Serum Concentrations of Persistent Organic Pollutants and Insulin Resistance Among Nondiabetic Adults

  2007cited by this paper
• Adiponectin Sensitizes Insulin Signaling by Reducing p70 S6 Kinase-mediated Serine Phosphorylation of IRS-1*

  2007cited by this paper
• A Strong Dose-Response Relation Between Serum Concentrations of Persistent Organic Pollutants and Diabetes

  2006cited by this paper
• The Atherosclerosis Risk in Communities Study

  2006cited by this paper
• Influence of amlodipine and atenolol on lipopolysaccharide (LPS)-induced serum concentrations of TNF-alpha, IL-1, IL-6 in spontaneously hypertensive rats (SHR).

  2006cited by this paper
• Inflammation and metabolic disorders

  2006cited by this paper
• Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain.

  2005cited by this paper
• The significance of the grasshopper effect on the atmospheric distribution of persistent organic substances

  2005cited by this paper
• Titan's ionosphere: Model comparisons with Cassini Ta data

  2005cited by this paper
• Independent association between inflammatory markers (C-reactive protein, interleukin-6, and TNF-α) and essential hypertension

  2005cited by this paper
• Physical activity, obesity, and the incidence of type 2 diabetes in a high-risk population.

  2003cited by this paper
• Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study.

  2003cited by this paper
• Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitro.

  2002cited by this paper
• Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence.

  2002cited by this paper
• Weight loss-induced rise in plasma pollutant is associated with reduced skeletal muscle oxidative capacity.

  2002cited by this paper
• Increase in plasma pollutant levels in response to weight loss in humans is related to in vitro subcutaneous adipocyte basal lipolysis

  2001cited by this paper
• Type 2 diabetes mellitus in Canada's first nations: status of an epidemic in progress.

  2000cited by this paper
• Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

  2000cited by this paper
• Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife.

  1998cited by this paper
• Aryl hydrocarbon receptor-mediated signal transduction.

  1997cited by this paper
• Pathophysiology of insulin resistance in human disease.

  1995cited by this paper
• Maternal transfer of organochlorine compounds in lake superior siscowet (Salvelinus namaycush siscowet) to their eggs

  1995cited by this paper
• Increased lipolysis and its consequences on gluconeogenesis in non-insulin-dependent diabetes mellitus.

  1992influential reference
• Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with 131I-labelled monoclonal antibody E48 IgG.

  1992cited by this paper
• Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man

  1985cited by this paper
• [Determination of plasma glucose by hexokinase-glucose-6-phosphate dehydrogenase method].

  1971cited by this paper

• Persistent organic pollutant concentrations in human pancreas and peripancreatic adipose tissues correlate with markers of beta cell dysfunction

  2025cites this paper
• Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food

  2024cites this paper
• Biochemical study of the risk of diabetes, prediabetic and insulin resistance in car painters and its association with mercury exposure: a retrospective case–control study

  2024cites this paper
• The diabetogenic effects of pesticides: Evidence based on epidemiological and toxicological studies.

  2023cites this paper
• Wearable sensor platforms for real-time monitoring and early warning of metabolic disorders in humans.

  2023cites this paper
• Measurement of diet quality among First Nations peoples in Canada and associations with health: a scoping review.

  2023cites this paper
• Association between heavy metal mercury in body fluids and tissues and diabetes mellitus: a systematic review and meta-analysis

  2023cites this paper
• Mercury Exposure and Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis

  2022cites this paper
• Persistent organic pollutants and β-cell toxicity: a comprehensive review

  2022cites this paper
• Human Pluripotent Stem Cells: A Unique Tool for Toxicity Testing in Pancreatic Progenitor and Endocrine Cells

  2021cites this paper
• Environmental contaminants and the disproportionate prevalence of type-2 diabetes mellitus among Indigenous Cree women in James Bay Quebec, Canada

  2021cites this paper
• Characterization and Application of Fe-Magnetic Materials and Nanomaterials for Application in the Aqueous Matrices Decontamination

  2021cites this paper
• Can selling traditional food increase food sovereignty for First Nations in northwestern Ontario (Canada)?

  2021cites this paper
• Endocrine Disruptors and the Induction of Insulin Resistance.

  2020cites this paper
• Identifying Potential biomarkers of insulin sensitivity and insulin resistance in obese patients

  2020cites this paper
• Association between type 2 diabetes and exposure to chlorinated persistent organic pollutants in Algeria: A case-control study.

  2020cites this paper
• Functional cytochrome P450 1A enzymes are induced in mouse and human islets following pollutant exposure

  2019cites this paper
• A review of organochlorine pesticides and polychlorinated biphenyls in Lebanon: Environmental and human contaminants.

  2019cites this paper
• Long-term metabolic consequences of acute dioxin exposure differ between male and female mice

  2019cites this paper
• Green Analysis: High Throughput Analysis of Emerging Pollutants in Plant Sap by Freeze-Thaw-Centrifugal Membrane Filtration Sample Preparation - HPLC-MS/MS Analysis.

  2019cites this paper
• Examining environmental contaminant mixtures among adults with type 2 diabetes in the Cree First Nation communities of Eeyou Istchee, Canada

  2019cites this paper
• Exposure to air pollution interacts with obesogenic nutrition to induce tissue-specific response patterns.

  2018cites this paper
• The Association Between Food Security and Diet Quality Among First Nations Living On-Reserve in Canada

  2018influential citation
• Fish Consumption and Nutritional Health among First Nations in Canada

  2018cites this paper
• Association of polybrominated diphenyl ethers in two fat compartments with increased risk of insulin resistance in obese individuals.

  2018cites this paper
• Type 2 Diabetes and Indigenous Peoples Diabetes Canada Clinical Practice Guidelines Expert Committee

  2018cites this paper
• Type 2 Diabetes and Indigenous Peoples.

  2018cites this paper
• Serum concentrations of selected organochlorine pesticides in a Lebanese population and their associations to sociodemographic, anthropometric and dietary factors: ENASB study

  2018influential citation
• Potential contribution of insecticide exposure and development of obesity and type 2 diabetes.

  2017cites this paper
• Effects of methyl mercury exposure on pancreatic beta cell development and function

  2017cites this paper
• Serum concentrations of polychlorinated biphenyls (PCBs) in a Lebanese population: ENASB study

  2017influential citation
• Environmental pollutants and type 2 diabetes: a review of human studies

  2017influential citation
• EFFECTS OF PERMETHRIN, A PYRETHROID INSECTICIDE, ON GLUCOSE AND LIPID METABOLISM

  2017cites this paper
• Is mercury exposure causing diabetes, metabolic syndrome and insulin resistance? A systematic review of the literature

  2017influential citation
• IMIDACLOPRID, A NEONICOTINOID INSECTICIDE, IMPAIRS LIPID AND GLUCOSE METABOLISM

  2017influential citation
• Association between fish consumption, dietary omega‐3 fatty acids and persistent organic pollutants intake, and type 2 diabetes in 18 First Nations in Ontario, Canada

  2017cites this paper
• Persistent Organic Pollutants and Concern Over the Link with Insulin Resistance Related Metabolic Diseases.

  2016cites this paper
• Low-Level Environmental Lead Exposure and Dysglycemia in Adult Individuals: Results from the Canadian Health and Measure Survey 2007–2011

  2016influential citation
• Reviews of Environmental Contamination and Toxicology

  2016cites this paper
• Reviews of Environmental Contamination and Toxicology

  2016cites this paper
• Persistent organic pollutants as risk factors for type 2 diabetes

  2015cites this paper
• A Systems Biology Approach Reveals Converging Molecular Mechanisms that Link Different POPs to Common Metabolic Diseases

  2015cites this paper
• Mercury and metabolic syndrome: a review of experimental and clinical observations

  2015cites this paper
• A Northern contaminant mixture impairs pancreas function in obese and lean JCR rats and inhibits insulin secretion in MIN6 cells.

  2015cites this paper
• Dose-Response Relationship Between Serum 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Diabetes Mellitus: A Meta-Analysis

  2015cites this paper
• Elevated Contaminants Contrasted with Potential Benefits of ω-3 Fatty Acids in Wild Food Consumers of Two Remote First Nations Communities in Northern Ontario, Canada

  2014cites this paper
• Le diabète de type 2 chez les Autochtones

  2013cites this paper