Abrogation of adriamycin toxicity in vivo by cycloheximide.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Biochemical Pharmacology

• Publication date

  1992-04-15

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/0006-2952(92)90697-HPMID 1374248
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Comparative effects of adriamycin and DNA-non-binding analogues on DNA, RNA, and protein synthesis in vitro

  2004cited by this paper
• Measurement of in vivo proliferation in human colorectal mucosa using bromodeoxyuridine.

  1992cited by this paper
• A low-temperature method for the isolation of small-intestinal epithelium along the crypt-villus axis.

  1991cited by this paper
• Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt.

  1990cited by this paper
• Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.

  1988cited by this paper
• Abrogation of etoposide-mediated cytotoxicity by cycloheximide.

  1988cited by this paper
• Proliferation-dependent topoisomerase II content as a determinant of antineoplastic drug action in human, mouse, and Chinese hamster ovary cells.

  1987cited by this paper
• Topoisomerase II as a target of anticancer drug action in mammalian cells.

  1987cited by this paper
• Proliferation dependence of topoisomerase II mediated drug action.

  1986cited by this paper
• Induction and/or selective retention of proteins in mammalian cells exposed to cycloheximide

  1985cited by this paper
• Effects of 9-OH-ellipticine on cell survival, macromolecular syntheses, and cell cycle progression in sensitive and resistant Chinese hamster lung cells.

  1985cited by this paper
• DNA topoisomerase activities in concanavalin A‐stimulated lymphocytes

  1984cited by this paper
• Delayed enhanced effects of Adriamycin on the X-irradiation-induced gastrointestinal toxicity in mice.

  1984cited by this paper
• Potentiation of DNA-reactive antineoplastic agents and protection against S-phase-specific agents by anguidine in Chinese hamster ovary cells.

  1983cited by this paper
• DNA topoisomerases from rat liver: physiological variations.

  1983cited by this paper
• A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis.

  1983cited by this paper
• The spatial organization of the hierarchical proliferative cells of the crypts of the small intestine into clusters of ‘synchronized’ cells

  1982cited by this paper
• Metabolic and ultrastructural aspects of the in vitro lysis of chronic lymphocytic leukemia cells by glucocorticoids.

  1982cited by this paper
• Reduction of 1-beta-D-arabinofuranosylcytosine and adriamycin cytotoxicity following cell cycle arrest by anguidine.

  1981cited by this paper
• The effects of adriamycin on murine duodenal crypt cell proliferation.

  1979cited by this paper
• Influence of adriamycin and adriamycin-radiation combination on jejunal proliferation in the mouse.

  1977cited by this paper
• Extreme sensitivity of some intestinal crypt cells to X and gamma irradiation.

  1977cited by this paper
• Extreme sensitivity of some intestinal crypt cells to X and γ irradiation

  1977cited by this paper
• Protective effects of an inhibitor of protein synthesis, cycloheximide, on bone marrow damage induced by cytosine arabinoside or nitrogen mustard.

  1975cited by this paper
• Protective effects of cycloheximide against 1-beta-D-arabinosylcytosine-induced intestinal lesions.

  1973cited by this paper
• A probable role for protein synthesis in intestinal epithelial cell damage induced in vivo by cytosine arabinoside, nitrogen mustard, or X-irradiation.

  1970cited by this paper
• Tissue distribution and disposition of daunomycin (NCS-82151) in mice: fluorometric and isotopic methods.

  1970cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Evaluation and validation of chemotherapy‐specific diarrhoea and histopathology in rats

  2022cites this paper
• Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies

  2021cites this paper
• Dark Agouti rat model of chemotherapy-induced mucositis: Establishment and current state of the art

  2015cites this paper
• Low-dose of multi-glycoside of Tripterygium wilfordii Hook. f., a natural regulator of TGF-β1/Smad signaling activity improves adriamycin-induced glomerulosclerosis in vivo.

  2014cites this paper
• ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response.

  2012cites this paper
• [Distribution and accumulation of antibiotics in cells and tissues and toxicity studies by immunocytochemistry].

  2011cites this paper
• Daunomycin accumulation and induction of programmed cell death in rat hair follicles

  2009cites this paper
• Novel fluorescence molecular imaging of chemotherapy-induced intestinal apoptosis.

  2009cites this paper
• Altering Chemosensitivity by Modulating Translation Elongation

  2009cites this paper
• Abolition of stress-induced protein synthesis sensitizes leukemia cells to anthracycline-induced death.

  2008cites this paper
• Immunocytochemical studies on the distribution pattern of daunomycin in rat gastrointestinal tract

  2007cites this paper
• Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: Relation to drug cytotoxicity and caspase-3 activation

  2005cites this paper
• Doxorubicin-induced Apoptosis in PC12 Cells

  2005cites this paper
• Brefeldin A and filipin distinguish two globotriaosyl ceramide/verotoxin-1 intracellular trafficking pathways involved in Vero cell cytotoxicity.

  2004cites this paper
• Adenovirus-mediated E2F-1 gene transfer sensitizes melanoma cells to apoptosis induced by topoisomerase II inhibitors.

  2002cites this paper
• Adenovirus-mediated E 2 F-1 Gene Transfer Sensitizes Melanoma Cells to Apoptosis Induced by Topoisomerase II Inhibitors 1

  2002cites this paper
• Antitumour activity and adverse reactions of combined treatment with chitosan and doxorubicin in tumour‐bearing mice

  2001cites this paper
• Activation of programmed cell death (apoptosis) by adriamycin in human neoplastic cells.

  2001cites this paper
• Topical administration of a doxorubicin-specific monoclonal antibody prevents drug-induced mouth apoptosis in mice

  2001cites this paper
• Potentiation of early necrotic death of glucose-starved pheochromocytoma 12 cells by nerve growth factor.

  2000cites this paper
• Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells.

  2000cites this paper
• Effect of altered duration of 41.5 degrees C whole body hyperthermia in combination with cis-diamminedichloroplatinum (II) on tumor and normal tissue apoptosis and tumor response in rats.

  1998cites this paper
• T-2 toxin induces thymic apoptosis in vivo in mice.

  1998cites this paper
• Anthracycline-derived chemotherapeutics in apoptosis and free radical cytotoxicity (Review).

  1998cites this paper
• In vitro cytotoxic activity of 1-decarboxy-3-oxo-ceanothic acid in a human ovarian adenocarcinoma cell line.

  1998cites this paper
• The influence of apoptosis on intestinal barrier integrity in rats.

  1998cites this paper
• Influence of cycloheximide-mediated downregulation of glucose transport on TNF alpha-induced apoptosis.

  1997cites this paper
• Effect of concentration on the cytotoxic mechanism of doxorubicin--apoptosis and oxidative DNA damage.

  1997cites this paper
• Apoptosis of hair follicle cells during doxorubicin-induced alopecia in rats.

  1996cites this paper
• Oral administration of anti-doxorubicin monoclonal antibody prevents chemotherapy-induced gastrointestinal toxicity in mice.

  1996cites this paper
• A Topoisomerase II Inhibitor, NK109, Induces DNA Single‐ and Double‐strand Breaks and Apoptosis

  1996cites this paper
• Doxorubicin-induced apoptosis in spontaneously hypertensive rats: differential effects in heart, kidney and intestine, and inhibition by ICRF-187.

  1996cites this paper
• Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

  1996cites this paper
• Pathways responsible for apoptosis in chick cardiomyocytes

  1996cites this paper
• Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals.

  1995cites this paper
• Inhibition of doxorubicin-induced cell death in vitro and in vivo by cycloheximide.

  1995cites this paper
• Apoptosis in health and disease.

  1995cites this paper
• Apoptosis and programmed cell death in health and disease.

  1994cites this paper
• bcl-2 gene enables rescue from in vitro myelosuppression (bone marrow cell death) induced by chemotherapy.

  1994cites this paper
• Cycloheximide inhibits the cytotoxicity of paclitaxel (Taxol).

  1994cites this paper
• The involvement of apoptosis in etoposide-induced thymic atrophy.

  1994cites this paper
• Doxorubicin-induced DNA degradation in murine thymocytes.

  1994cites this paper
• Effect of different oxygen pressures and N,N'-diphenyl-p-phenylenediamine on Adriamycin toxicity to cultured neonatal rat heart myocytes.

  1994cites this paper
• Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells.

  1994cites this paper
• Programmed cell death — many questions still to be answered

  1994cites this paper
• Transfection with a bcl-2 expression vector protects transplanted bone marrow from chemotherapy-induced myelosuppression.

  1994cites this paper
• Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells.

  1993cites this paper
• Modulatory effects of tamoxifen and recombinant human alpha-interferon on doxorubicin resistance.

  1993cites this paper
• Modulatory Effects of Tamoxifen and Recombinant Human α-Interferon on Doxorubicin Resistance

  1993cites this paper
• Taxol in combination with doxorubicin or etoposide possible antagonism in vitro

  1993cites this paper
• Taxol in Combination with Doxorubicin or Etoposide

  1993cites this paper
• Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose.

  1993cites this paper
• Adriamycin and daunomycin induce programmed cell death (apoptosis) in tumour cells.

  1993cites this paper