Pursuing the middleman

By the mid-1970s, the idea of a transmembrane molecule linking the cytoskeleton to the extracellular matrix (ECM) had some supporting evidence. Adhesion molecules were hot in areas ranging from developmental biology to tumor biology, and the mounting suggestive evidence that a “fibronectin receptor” existed made it a “Holy Grail” for the next decade, recalls Richard Hynes, discoverer of fibronectin, in a memoir (Hynes, 2004).

• Publication year

  2005

• Venue

  Journal of Cell Biology

• Publication date

  2005-11-21

• Fields of study

  Biology

• Identifiers
  DOI 10.1083/JCB1714FTA1PMCID 2258052
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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