The anxiety‐like phenotype of 5‐HT1A receptor null mice is associated with genetic background‐specific perturbations in the prefrontal cortex GABA–glutamate system

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Neurochemistry

• Publication date

  2006-11-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1111/j.1471-4159.2006.04129.xPMID 16925594
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Strain background effects and genetic modifiers of hearing in mice.

  2006cited by this paper
• Tonic excitation and inhibition of neurons: ambient transmitter sources and computational consequences.

  2005cited by this paper
• 5-HT1A receptor-effector system responsivity in panic disorder

  2005cited by this paper
• Infusions of midazolam into the medial prefrontal cortex produce anxiolytic effects in the elevated plus-maze and shock-probe burying tests.

  2004cited by this paper
• Reduced Serotonin Type 1A Receptor Binding in Panic Disorder

  2004cited by this paper
• Co-expression and in vivo interaction of serotonin1A and serotonin2A receptors in pyramidal neurons of prefrontal cortex.

  2004cited by this paper
• Neurobiological correlates of high (HAB) versus low anxiety-related behavior (LAB): differential Fos expression in HAB and LAB rats.

  2004cited by this paper
• Variability in the Benzodiazepine Response of Serotonin 5-HT1A Receptor Null Mice Displaying Anxiety-Like Phenotype: Evidence for Genetic Modifiers in the 5-HT-Mediated Regulation of GABAA Receptors

  2004influential reference
• Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs.

  2003cited by this paper
• Brain activation to phobia-related pictures in spider phobic humans: an event-related functional magnetic resonance imaging study.

  2003cited by this paper
• In vivo efflux of serotonin in the dorsal raphe nucleus of 5‐HT1A receptor knockout mice

  2003cited by this paper
• Excitotoxic lesions of the medial prefrontal cortex attenuate fear responses in the elevated-plus maze, social interaction and shock probe burying tests.

  2003cited by this paper
• Effects of Isoflurane and Propofol on Glutamate and GABA Transporters in Isolated Cortical Nerve Terminals

  2003influential reference
• The neurobiology and control of anxious states.

  2003cited by this paper
• Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

  2002influential reference
• Glutamate uptake.

  2001cited by this paper
• Modifier genes in mice and humans

  2001cited by this paper
• Functional MRI changes during panic anticipation and imagery exposure

  2001cited by this paper
• Differential effects of 5-HT1A receptor deletion upon basal and fluoxetine-evoked 5-HT concentrations as revealed by in vivo microdialysis.

  2001cited by this paper
• SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder.

  2000cited by this paper
• Genealogies of mouse inbred strains

  2000cited by this paper
• Genetic Inactivation of the Serotonin1A Receptor in Mice Results in Downregulation of Major GABAA Receptor α Subunits, Reduction of GABAA Receptor Binding, and Benzodiazepine-Resistant Anxiety

  2000cited by this paper
• Regulation of the gene encoding tumor necrosis factor alpha (TNF-alpha) in the rat brain and pituitary in response in different models of systemic immune challenge.

  1999cited by this paper
• Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice.

  1998cited by this paper
• Increased anxiety of mice lacking the serotonin1A receptor.

  1998cited by this paper
• Serotonin receptor 1A knockout: an animal model of anxiety-related disorder.

  1998cited by this paper
• Recombinant adenovirus-mediated expression in nervous system of genes coding for ion channels and other molecules involved in synaptic function.

  1998cited by this paper
• Determination of ?-aminobutyric acid in microdialysis samples by microbore column liquid chromatogra

  1998cited by this paper
• Determination of gamma-aminobutyric acid in microdialysis samples by microbore column liquid chromatography and fluorescence detection.

  1998cited by this paper
• What do the mushroom bodies do for the insect brain? an introduction.

  1998cited by this paper
• Decreased brain GABA(A)-benzodiazepine receptor binding in panic disorder: preliminary results from a quantitative PET study.

  1998cited by this paper
• Substrate binding sites of glutamate transporters and structurally related neutral amino acid transporters.

  1997influential reference
• Effects of an electrolytic lesion of the prelimbic area on anxiety-related and cognitive tasks in the rat.

  1996cited by this paper
• Immunocytochemical localization of serotonin1A receptors in the rat central nervous system

  1996cited by this paper
• Ultrastructural localization of 5‐hydroxytryptamine1A receptors in the rat brain

  1996cited by this paper
• An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

  1995influential reference
• Phenotypic diversity, allelic series and modifier genes

  1994cited by this paper
• The neuroanatomical basis of anxiety.

  1992cited by this paper
• 5-Hydroxytryptamine2 and 5-hydroxytryptamine 1A receptors mediate opposing responses on membrane excitability in rat association cortex.

  1991cited by this paper
• Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain--a combined in situ hybridisation/in vitro receptor autoradiographic study.

  1991cited by this paper
• Quantitative autoradiographic mapping of serotonin receptors in the rat brain. I. Serotonin-1 receptors.

  1985cited by this paper
• Behavioural despair in rats: a new model sensitive to antidepressant treatments.

  1978cited by this paper
• INTERNATIONAL SOCIETY FOR NEUROCHEMISTRY

  1976cited by this paper

• Inhibitory dysfunction and social processing difficulties in autism: A comprehensive narrative review.

  2023cites this paper
• Chronic exposure to metam sodium-based pesticide in mice during adulthood elevated anxiety and depression-like behaviors: involvement of serotoninergic depletion and gut microbiota dysbiosis.

  2023cites this paper
• One-year-later spontaneous EEG features predict visual exploratory human phenotypes

  2022cites this paper
• Decreased kynurenine pathway potentiate resilience to social defeat effect on cocaine reward.

  2021cites this paper
• Experimental Anxiety Model for Anxiety Disorders: Relevance to Drug Discovery.

  2020cites this paper
• Turning Strains into Strengths for Understanding Psychiatric Disorders

  2020cites this paper
• Enhanced activity of pyramidal neurons in the infralimbic cortex drives anxiety behavior

  2019cites this paper
• The Serotonin Brainstem Hypothesis for the Sudden Infant Death Syndrome.

  2019cites this paper
• Disturbo da stress post traumatico nei pazienti adulti: revisione integrativa sui fattori biologici

  2017cites this paper
• Metabotropic Glutamate Receptors – Regulation of Acute and Chronic Stress-Related Behavior and Physiology

  2017cites this paper
• Neurobiology of Chronic Stress-Related Psychiatric Disorders: Evidence from Molecular Imaging Studies

  2017cites this paper
• Relief from detrimental consequences of chronic psychosocial stress in mice deficient for the metabotropic glutamate receptor subtype 7

  2017cites this paper
• Dysregulation of the axonal trafficking of nuclear‐encoded mitochondrial mRNA alters neuronal mitochondrial activity and mouse behavior

  2014cites this paper
• The Correlation of the Neuronal Long‐Range Temporal Correlations, Avalanche Dynamics with the Behavioral Scaling Laws and Interindividual Variability

  2014cites this paper
• Neuronal long-range temporal correlations and avalanche dynamics are correlated with behavioral scaling laws

  2013cites this paper
• Serotonin 5-HT1A Receptors as Targets for Agents to Treat Psychiatric Disorders: Rationale and Current Status of Research

  2013cites this paper
• Decreased GABAA Receptor Binding in the Medullary Serotonergic System in the Sudden Infant Death Syndrome

  2011cites this paper
• A and 5 HT 1 B receptors of medial prefrontal cortex modulate anxiogenic-like ehaviors in rats

  2011cites this paper
• 5HT(1A) and 5HT(1B) receptors of medial prefrontal cortex modulate anxiogenic-like behaviors in rats.

  2011cites this paper
• Qui non proficit, deficit: experimental models for 'integrative' research of affective disorders.

  2010cites this paper
• Putative targeting of Dopamine D2 receptor function in Reward Deficiency Syndrome (RDS) by Synaptamine Complex™ Variant (KB220): Clinical trial showing anti-anxiety effects

  2009cites this paper
• Pharmacological Alterations of Anxious Behaviour in Mice Depending on Both Strain and the Behavioural Situation

  2009cites this paper
• Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience.

  2009influential citation
• Anxiety Disorders: Macromolecular Pathways and Interactions

  2008cites this paper
• 5-HT1A gene variants and psychiatric disorders: a review of current literature and selection of SNPs for future studies.

  2008cites this paper
• Pitfalls in the interpretation of genetic and pharmacological effects on anxiety-like behaviour in rodents

  2008cites this paper
• Experiential and genetic contributions to depressive- and anxiety-like disorders: clinical and experimental studies.

  2008cites this paper
• Control of hormonal stress reactivity by the endogenous opioid system.

  2008cites this paper
• Comparisons of mass spectrometry compatible surfactants for global analysis of the mammalian brain proteome.

  2008cites this paper
• Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease.

  2008cites this paper
• Use of Mice with Targeted Genetic Inactivation in the Serotonergic System for the Study of Anxiety

  2007cites this paper
• Candidate genes for panic disorder: insight from human and mouse genetic studies

  2007cites this paper
• Mice deficient in the alpha subunit of Gz show changes in pre-pulse inhibition, anxiety and responses to 5-HT1A receptor stimulation, which are strongly dependent on the genetic background

  2007cites this paper