Manoyl Oxide ( 13 R ) , the Biosynthetic Precursor of Forskolin , Is Synthesized in Specialized Root Cork Cells in Coleus forskohlii 1 [ W ] [ OPEN ]

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• High-throughput testing of terpenoid biosynthesis candidate genes using transient expression in Nicotiana benthamiana.

  2014cited by this paper
• The Oil Bodies of Liverworts: Unique and Important Organelles in Land Plants

  2013cited by this paper
• CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts

  2013cited by this paper
• Plant P450s as versatile drivers for evolution of species-specific chemical diversity

  2013cited by this paper
• Plant Sterol Metabolism. Δ7-Sterol-C5-Desaturase (STE1/DWARF7), Δ5,7-Sterol-Δ7-Reductase (DWARF5) and Δ24-Sterol-Δ24-Reductase (DIMINUTO/DWARF1) Show Multiple Subcellular Localizations in Arabidopsis thaliana (Heynh) L

  2013cited by this paper
• Gene Discovery of Modular Diterpene Metabolism in Nonmodel Systems1[W][OA]

  2013influential reference
• Phospholipids and lipid droplets.

  2013cited by this paper
• Forskolin: upcoming antiglaucoma molecule.

  2012influential reference
• Thematic Review Series: Lipid Droplet Synthesis and Metabolism: from Yeast to Man Biogenesis and functions of lipid droplets in plants

  2012cited by this paper
• Bifunctional cis-Abienol Synthase from Abies balsamea Discovered by Transcriptome Sequencing and Its Implications for Diterpenoid Fragrance Production*

  2012cited by this paper
• Assessing the Biosynthetic Capabilities of Secretory Glands in Citrus Peel1[W][OA]

  2012cited by this paper
• Characterization of two genes for the biosynthesis of the labdane diterpene Z-abienol in tobacco (Nicotiana tabacum) glandular trichomes.

  2012influential reference
• Localization of Oleuropeyl Glucose Esters and a Flavanone to Secretory Cavities of Myrtaceae

  2012cited by this paper
• IeCPS2 is potentially involved in the biosynthesis of pharmacologically active Isodon diterpenoids rather than gibberellin.

  2012influential reference
• Laticifer-Specific cis-Prenyltransferase Silencing Affects the Rubber, Triterpene, and Inulin Content of Taraxacum brevicorniculatum12[C][W]

  2012cited by this paper
• The Synthesis and Storage Sites of Phenolic Compounds in the Root and Rhizome of Echinacea purpurea

  2012influential reference
• Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture

  2012influential reference
• Labdane-type diterpenoids from hairy root cultures of Coleus forskohlii, possible intermediates in the biosynthesis of forskolin.

  2012influential reference
• Not just fat: the structure and function of the lipid droplet.

  2011cited by this paper
• The dynamic roles of intracellular lipid droplets: from archaea to mammals

  2011cited by this paper
• MATE2 Mediates Vacuolar Sequestration of Flavonoid Glycosides and Glycoside Malonates in Medicago truncatula[C][W][OA]

  2011cited by this paper
• The family of terpene synthases in plants: a mid-size family of genes for specialized metabolism that is highly diversified throughout the kingdom.

  2011cited by this paper
• Transcriptome mining, functional characterization, and phylogeny of a large terpene synthase gene family in spruce (Picea spp.)

  2011cited by this paper
• Terpenoids inhibit Candida albicans growth by affecting membrane integrity and arrest of cell cycle.

  2011cited by this paper
• Evolution of Diterpene Metabolism: Sitka Spruce CYP720B4 Catalyzes Multiple Oxidations in Resin Acid Biosynthesis of Conifer Defense against Insects1[C][W][OA]

  2011influential reference
• Identification of phenolic compounds in isolated vacuoles of the medicinal plant Catharanthus roseus and their interaction with vacuolar class III peroxidase: an H₂O₂ affair?

  2011cited by this paper
• Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals.

  2011cited by this paper
• CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice.

  2011cited by this paper
• Lipid droplets: A dynamic organelle moves into focus

  2010cited by this paper
• Terpenoid biosynthesis and specialized vascular cells of conifer defense.

  2010cited by this paper
• Identification and Functional Characterization of Monofunctional ent-Copalyl Diphosphate and ent-Kaurene Synthases in White Spruce Reveal Different Patterns for Diterpene Synthase Evolution for Primary and Secondary Metabolism in Gymnosperms 1 [ W ] [ OA ]

  2010influential reference
• A Copal-8-ol Diphosphate Synthase from the Angiosperm Cistus creticus subsp. creticus Is a Putative Key Enzyme for the Formation of Pharmacologically Active, Oxygen-Containing Labdane-Type Diterpenes1[OA]

  2010influential reference
• EST analysis and annotation of transcripts derived from a trichome-specific cDNA library from Salvia fruticosa

  2010cited by this paper
• A genomics resource for investigating regulation of essential oil production in Lavandula angustifolia

  2010cited by this paper
• Plectranthus barbatus: A Review of Phytochemistry, Ethnobotanical Uses and Pharmacology – Part 2

  2010cited by this paper
• Plectranthus barbatus: A Review of Phytochemistry, Ethnobotanical Uses and Pharmacology – Part 1

  2010cited by this paper
• Coleus forskohlii - a comprehensive review on morphology, phytochemistry and pharmacological aspects.

  2010cited by this paper
• Two rings in them all: the labdane-related diterpenoids.

  2010cited by this paper
• Endogenous Diterpenes Derived from ent-Kaurene, a Common Gibberellin Precursor, Regulate Protonema Differentiation of the Moss Physcomitrella patens1[W][OA]

  2010cited by this paper
• CYP76M7 Is an ent-Cassadiene C11α-Hydroxylase Defining a Second Multifunctional Diterpenoid Biosynthetic Gene Cluster in Rice[W][OA]

  2009cited by this paper
• A Functional Genomics Approach to Tanshinone Biosynthesis Provides Stereochemical Insights

  2009influential reference
• Expedient construction of the Ziegler intermediate useful for the synthesis of forskolin via consecutive rearrangements.

  2009cited by this paper
• Harnessing plant trichome biochemistry for the production of useful compounds.

  2008cited by this paper
• Antibacterial activity of labdane diterpenoids from Stemodia foliosa.

  2008cited by this paper
• Hydrophobic characterization of intracellular lipids in situ by Nile Red red/yellow emission ratio.

  2008cited by this paper
• beta-Glucosidases as detonators of plant chemical defense.

  2008cited by this paper
• A systems biology investigation of the MEP/terpenoid and shikimate/phenylpropanoid pathways points to multiple levels of metabolic control in sweet basil glandular trichomes.

  2008cited by this paper
• Mechanisms of resistance to self-produced toxic secondary metabolites in plants

  2008cited by this paper
• Laticifers: An historical perspective

  2008cited by this paper
• Untargeted large-scale plant metabolomics using liquid chromatography coupled to mass spectrometry

  2007cited by this paper
• Flavonoid Biosynthesis in Barley Primary Leaves Requires the Presence of the Vacuole and Controls the Activity of Vacuolar Flavonoid Transport1

  2007cited by this paper
• The function of terpene natural products in the natural world.

  2007cited by this paper
• Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function[W]

  2007cited by this paper
• A forskolin derivative, FSK88, induces apoptosis in human gastric cancer BGC823 cells through caspase activation involving regulation of Bcl‐2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release

  2006cited by this paper
• Advancing uracil-excision based cloning towards an ideal technique for cloning PCR fragments

  2006cited by this paper
• Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants.

  2006cited by this paper
• Plectranthus: a review of ethnobotanical uses.

  2006cited by this paper
• [Studies on the chemical constituents in root of Coleus forskohlii].

  2005influential reference
• Loblolly pine abietadienol/abietadienal oxidase PtAO (CYP720B1) is a multifunctional, multisubstrate cytochrome P450 monooxygenase

  2005cited by this paper
• PRODUCTION AND CELLULAR LOCALIZATION OF NEUTRAL LONG‐CHAIN LIPIDS IN THE HAPTOPHYTE ALGAE ISOCHRYSIS GALBANA AND EMILIANIA HUXLEYI 1

  2005influential reference
• Pharmacokinetics and a simulation model of colforsin daropate, new forskolin derivative inotropic vasodilator, in patients undergoing coronary artery bypass grafting.

  2004cited by this paper
• The Biochemical and Molecular Basis for the Divergent Patterns in the Biosynthesis of Terpenes and Phenylpropenes in the Peltate Glands of Three Cultivars of Basil1

  2004cited by this paper
• Localization of salvinorin A and related compounds in glandular trichomes of the psychoactive sage, Salvia divinorum.

  2004cited by this paper
• An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus.

  2003cited by this paper
• Methyl Jasmonate Induces Traumatic Resin Ducts, Terpenoid Resin Biosynthesis, and Terpenoid Accumulation in Developing Xylem of Norway Spruce Stems1

  2002cited by this paper
• Elucidation of the Methylerythritol Phosphate Pathway for Isoprenoid Biosynthesis in Bacteria and Plastids. A Metabolic Milestone Achieved through Genomics1

  2002cited by this paper
• A simple and rapid method for the differentiation of C-13 manoyl oxide epimers in biologically important samples using GC-MS analysis supported with NMR spectroscopy and computational chemistry results.

  2002cited by this paper
• Cardiovascular and adenylate cyclase stimulating effects of colforsin daropate, a water-soluble forskolin derivative, compared with those of isoproterenol, dopamine and dobutamine.

  2002cited by this paper
• Essential oils and hexane extracts from leaves and fruits of Cistus monspeliensis. Cytotoxic activity of ent-13-epi-manoyl oxide and its isomers.

  2001cited by this paper
• Regulation of monoterpene accumulation in leaves of peppermint.

  2000cited by this paper
• Structure and antibacterial activity ofp6 new labdane diterpenoid from Salvia leriaefolia.

  2000cited by this paper
• Cytotoxic activity and antiproliferative effects of a new semi-synthetic derivative of Ent-3 beta-hydroxy-13-epi-manoyl oxide on human leukemic cell lines.

  1999cited by this paper
• Novel labdane diterpenes from the insecticidal plant hyptis spicigera1

  1999cited by this paper
• ChloroP, a neural network‐based method for predicting chloroplast transit peptides and their cleavage sites

  1999cited by this paper
• Forskolin derivatives with increased selectivity for cardiac adenylyl cyclase.

  1998cited by this paper
• The adenylyl and guanylyl cyclase superfamily.

  1998cited by this paper
• Identification of essential oil components by gas chromatography/mass spectroscopy.

  1995cited by this paper
• Non-Cytotoxic Inhibition of Macrophage Eicosanoid Biosynthesis and Effects on Leukocyte Functions and Reactive Oxygen Species of Two Novel Anti-Inflammatory Plant Diterpenoids

  1994cited by this paper
• Natural Metabolites of ent-13-epi-Manoyl Oxide and Other Cytotoxic Diterpenes from the Resin "LADANO" of Cistus creticus.

  1994cited by this paper
• Coleus barbatus (C.forskohlii)(Lamiaceae) and the potential new drug forskolin (Coleonol)

  1987cited by this paper
• Forskolin: From an Ayurvedic Remedy to a Modern Agent

  1985cited by this paper
• Effects of beta-pinene on yeast membrane functions

  1985cited by this paper
• Forskolin, adenylate cyclase, and cell physiology: an overview.

  1984cited by this paper
• An abietane diterpene from the labiate Coleus barbatus

  1984cited by this paper
• Isolation, structure determination, and absolute configuration of barbatusol, a new bioactive diterpene with a rearranged abietane skeleton from the labiate coleus barbatus

  1983influential reference
• Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

  1981cited by this paper
• Structures and stereochemistry of new labdane diterpiniods from coleus forskohlii briq.

  1977influential reference

• Uncovering a miltiradiene biosynthetic gene cluster in the Lamiaceae reveals a dynamic evolutionary trajectory

  2023cites this paper
• Construction and optimization of Saccharomyces cerevisiae for synthesizing forskolin

  2022cites this paper
• Biodiscoveries within the Australian plant genus Eremophila based on international and interdisciplinary collaboration: results and perspectives on outstanding ethical dilemmas

  2022cites this paper
• Tripterygium wilfordii cytochrome P450s catalyze the methyl shift and epoxidations in the biosynthesis of triptonide

  2022cites this paper
• Exploring Uncharted Territories of Plant Specialized Metabolism in the Postgenomic Era.

  2020cites this paper
• Functional Diversity of Diterpene Synthases in the Biofuel Crop Switchgrass1[OPEN]

  2018cites this paper
• Biosynthesis of bioactive diterpenoids in the medicinal plant Vitex agnus‐castus

  2018cites this paper
• Functional Characterization of Two Class II Diterpene Synthases Indicates Additional Specialized Diterpenoid Pathways in Maize (Zea mays)

  2018cites this paper
• Functional Diversification of Kaurene Synthase-Like Genes in Isodon rubescens1[OPEN]

  2017influential citation
• Functional Diversi fi cation of Kaurene Synthase-Like Genes in Isodon rubescens 1 [ OPEN ]

  2017influential citation
• Integrative Approaches for the Identification and Localization of Specialized Metabolites in Tripterygium Roots1[OPEN]

  2016cites this paper
• Integrative Approaches for the Identi fi cation and Localization of Specialized Metabolites in Tripterygium Roots 1 [ OPEN ]

  2016cites this paper
• Stable heterologous expression of biologically active terpenoids in green plant cells

  2015cites this paper
• Metabolic Engineering of Synechocystis sp. PCC 6803 for Production of the Plant Diterpenoid Manoyl Oxide

  2015cites this paper
• Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza1[OPEN]

  2015cites this paper
• Comparative Transcriptomics Unravel Biochemical Specialization of Leaf Tissues of Stevia for Diterpenoid Production1

  2015influential citation
• Genus Cistus: a model for exploring labdane-type diterpenes' biosynthesis and a natural source of high value products with biological, aromatic, and pharmacological properties

  2014cites this paper