Preischemic Hyperglycemia Enhances Postischemic Depression of Cerebral Metabolic Rate

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Journal of Cerebral Blood Flow and Metabolism

• Publication date

  1989-08-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1038/jcbfm.1989.71PMID 2738114
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2004cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1986influential reference
• Selective central nervous system calcium channel blockers--a new class of anticonvulsant agents.

  1986cited by this paper
• Role of the substantia nigra in GABA-mediated anticonvulsant actions.

  1986cited by this paper
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  1986cited by this paper
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  1985cited by this paper
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  1985cited by this paper
• Mitochondrial Response to Transient Forebrain Ischemia and Recirculation in the Rat

  1984cited by this paper
• Cerebral circulation and metabolism.

  1984cited by this paper
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  1984cited by this paper
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  1983cited by this paper
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  1982cited by this paper
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  1982cited by this paper
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  1981cited by this paper
• Cell Damage in the Brain: A Speculative Synthesis

  1981cited by this paper
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  1981cited by this paper
• Local cerebral glucose utilization and blood flow during metabolic acidosis.

  1981cited by this paper
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• Local cerebral glucose consumption during insulin-induced hypoglycemia, and in the recovery period following glucose administration.

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  1978cited by this paper
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  1978cited by this paper
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  1978cited by this paper
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  1973cited by this paper
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  year unknowncited by this paper

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• GLUT1 and GLUT3 gene expression in gerbil brain following brief ischemia: an in situ hybridization study.

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