Antitumor activity of total paeony glycoside against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Medical Oncology

• Publication date

  2012-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12032-011-9909-9PMID 21452044
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010cited by this paper
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  2010cited by this paper
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  2010influential reference
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  2010influential reference
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  2010cited by this paper
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  2010cited by this paper
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  2010influential reference
• [Comparative protein analysis of K562 cell apoptosis induced by 6-gingerol].

  2010cited by this paper
• Pillars Article: CD28 Costimulation Can Promote T Cell Survival by Enhancing the Expression of Bcl-xL. Immunity. 1995. 3: 87–98

  2010cited by this paper
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  2010influential reference
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2009cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
• Cleavage of Bax enhances its cell death function.

  2000cited by this paper
• [Study on activating blood and eliminating stasis of total paeony glycoside(TPG)].

  2000cited by this paper
• CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

  1995influential reference

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  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018influential citation
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper