Pygo2 regulates β-catenin–induced activation of hair follicle stem/progenitor cells and skin hyperplasia

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2014-06-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/pnas.1311395111PMID 24982158PMCID PMC4104891
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2014cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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• BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.

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• Pygo2 regulates histone gene expression and H3 K56 acetylation in human mammary epithelial cells

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• Mechanisms regulating epidermal stem cells

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• Jarid2 regulates mouse epidermal stem cell activation and differentiation

  2011cited by this paper
• SnapShot: hair follicle stem cells.

  2011cited by this paper
• Genome-wide maps of histone modifications unwind in vivo chromatin states of the hair follicle lineage.

  2011cited by this paper
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  2010cited by this paper
• Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death

  2010cited by this paper
• The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein.

  2009cited by this paper
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  2009cited by this paper
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  2009cited by this paper
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  2009cited by this paper
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  2009cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
• What's taking so long? S-phase entry from quiescence versus proliferation

  2007influential reference
• The stem cell race

  2007cited by this paper
• p63 Is essential for the proliferative potential of stem cells in stratified epithelia.

  2007cited by this paper
• Lhx2 Maintains Stem Cell Character in Hair Follicles

  2006influential reference
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  2005cited by this paper
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  2005influential reference
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  2004cited by this paper
• Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis

  2003cited by this paper
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  2003cited by this paper
• Label-retaining cells in the bulge region are directed to cell death after plucking, followed by healing from the surviving hair germ.

  2002cited by this paper
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  2001cited by this paper
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  2001influential reference
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
• De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin

  1998cited by this paper
• DNA damage activates p53 through a phosphorylation-acetylation cascade.

  1998cited by this paper

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• The Role of p53 in Regulating Chronic Inflammation and PANoptosis in Diabetic Wounds

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  2024cites this paper
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  2021cites this paper
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  2017cites this paper
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• Pygo2 activates MDR1 expression and mediates chemoresistance in breast cancer via the Wnt/β-catenin pathway

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• WNT Signaling in Cutaneous Squamous Cell Carcinoma: A Future Treatment Strategy?

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  2015influential citation
• Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation*

  2015cites this paper
• The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: Implications in targeted cancer therapies

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• Epigenetic Regulation of Epidermal Stem Cell Biomarkers and Their Role in Wound Healing

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• The E3 ligase Itch knockout mice show hyperproliferation and wound healing alteration

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• Abnormal nuclear expression of Pygopus‐2 in human primary hepatocellular carcinoma correlates with a poor prognosis

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