The Response of a Co-culture Lung Model to Fine and Ultrafine Particles of Incinerator Fly Ash at the Air–liquid Interface

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Alternatives to laboratory animals : ATLA

• Publication date

  2008-07-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1177/026119290803600306PMID 18662093
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In Vitro Testing of Inhalable Fly Ash at the Air Liquid Interface

  2008influential reference
• Dose-controlled exposure of A549 epithelial cells at the air-liquid interface to airborne ultrafine carbonaceous particles.

  2006cited by this paper
• Toxic Potential of Materials at the Nanolevel

  2006cited by this paper
• Heme oxygenase-1 gene expression in human alveolar epithelial cells (A549) following exposure to whole cigarette smoke on a direct in vitro exposure system.

  2006cited by this paper
• The role of reactive oxygen species and oxidative stress in mediating particulate matter injury.

  2006cited by this paper
• Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silica-induced lung injury.

  2006cited by this paper
• Molecular Mechanisms Activating the Nrf2-Keap1 Pathway of Antioxidant Gene Regulation

  2005cited by this paper
• Cardiovascular Effects of Fine and Ultrafine Particles

  2005cited by this paper
• Heme oxygenase-1: from bench to bedside.

  2005cited by this paper
• Glutathione, Stress Responses, and Redox Signaling in Lung Inflammation

  2005cited by this paper
• Direct exposure methods for testing native atmospheres.

  2005cited by this paper
• Exposure of Bronchial Epithelial Cells to Whole Cigarette Smoke: Assessment of Cellular Responses

  2005cited by this paper
• Particle and Fibre Toxicology Combustion-derived Nanoparticles: a Review of Their Toxicology following Inhalation Exposure

  2005cited by this paper
• Modified procedure of a direct in vitro exposure system for mammalian cells to whole cigarette smoke.

  2004cited by this paper
• Comparative Assessment of Toxicities of Mainstream Smoke from Commercial Cigarettes

  2004cited by this paper
• Exposure technique for a lung specific bioassay for the assessment of industrial ultra fine particle-emissions

  2004cited by this paper
• Nrf2 Is a Key Transcription Factor That Regulates Antioxidant Defense in Macrophages and Epithelial Cells: Protecting against the Proinflammatory and Oxidizing Effects of Diesel Exhaust Chemicals1

  2004cited by this paper
• Gas-/Partikelwechselwirkung chlorierter Aromaten bei der Rauchgasreinigung von Müllverbrennungsanlagen

  2003cited by this paper
• Monitoring cellular responses of engine-emitted particles by using a direct air-cell interface deposition technique.

  2003cited by this paper
• A Method for the In Vitro Exposure of Human Cells to Environmental and Complex Gaseous Mixtures: Application to Various Types of Atmosphere

  2002cited by this paper
• Comparison of the Pro-Oxidative and Proinflammatory Effects of Organic Diesel Exhaust Particle Chemicals in Bronchial Epithelial Cells and Macrophages1

  2002cited by this paper
• In vitro effects of incinerator fly ash on pulmonary macrophages and epithelial cells.

  2002cited by this paper
• Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage.

  2002cited by this paper
• Deposition of fine and ultrafine aerosol particles during exposure at the air/cell interface

  2002cited by this paper
• Inflammatory lung injury after bronchial instillation of air pollution particles.

  2001cited by this paper
• Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994.

  2000cited by this paper
• Oxidative stress and regulation of glutathione in lung inflammation.

  2000cited by this paper
• Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress.

  1999cited by this paper
• CULTEX--a new system and technique for the cultivation and exposure of cells at the air/liquid interface.

  1999cited by this paper
• Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine (PM2.5) and coarse particles (PM10-2.5) in outdoor and indoor air.

  1999cited by this paper
• In vitro effects of nitrogen dioxide on the release of nitric oxide by bovine alveolar macrophages

  1998cited by this paper
• In vitro effects of nitrogen dioxide on the release of nitric oxide by bovine alveolar macrophages.

  1998cited by this paper
• Diesel exhaust particles induced release of interleukin 6 and 8 by (primed) human bronchial epithelial cells (BEAS 2B) in vitro.

  1997cited by this paper
• Charakterisierung von Filterstäuben aus Abfallverbrennungsanlagen

  1997cited by this paper
• Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA‐primed THP‐1 cells

  1996cited by this paper
• Pulmonary inflammatory, chemokine, and mutagenic responses in rats after subchronic inhalation of carbon black.

  1996cited by this paper
• Sv40‐induced immortalization and ras‐transformation of human bronchial epithelial cells

  1995cited by this paper
• Microtiter plate assay for the measurement of glutathione and glutathione disulfide in large numbers of biological samples.

  1990cited by this paper
• Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)

  1980cited by this paper
• [La culture cellulaire en phase gazeuse. Un nouveau modèle expérimental d'étude in vitro des activités des macrophages alvéolaires].

  1977cited by this paper
• Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues.

  1969cited by this paper

• Exploring the efficacy and constraints of platinum nanoparticles as adjuvant therapy in silicosis management

  2025cites this paper
• Generation, characterization, and toxicological assessment of reference ultrafine soot particles with different organic content for inhalation toxicological studies.

  2024cites this paper
• Aerosol exposure at air-liquid-interface (AE-ALI) in vitro toxicity system characterisation: Particle deposition and the importance of air control responses.

  2024cites this paper
• Transferability and reproducibility of exposed air-liquid interface co-culture lung models.

  2023cites this paper
• On the Path to Predicting Immune Responses in the Lung: Modeling the Pulmonary Innate Immune system at the Air-Liquid Interface (ALI).

  2023cites this paper
• Development of a standardized in vitro approach to evaluate microphysical, chemical, and toxicological properties of combustion-derived fine and ultrafine particles.

  2022cites this paper
• Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells

  2022cites this paper
• Comparing α-Quartz-Induced Cytotoxicity and Interleukin-8 Release in Pulmonary Mono- and Co-Cultures Exposed under Submerged and Air-Liquid Interface Conditions

  2022cites this paper
• Biofabricated platinum nanoparticles: therapeutic evaluation as a potential nanodrug against breast cancer cells and drug-resistant bacteria

  2021cites this paper
• Breathing in vitro: Designs and applications of engineered lung models

  2021cites this paper
• β-caryophyllene ameliorated obesity-associated airway hyperresponsiveness through some non-conventional targets.

  2021cites this paper
• Air–Liquid Interface Exposure of Lung Epithelial Cells to Low Doses of Nanoparticles to Assess Pulmonary Adverse Effects

  2020cites this paper
• Anisotropic Platinum Nanoparticle-Induced Cytotoxicity, Apoptosis, Inflammatory Response, and Transcriptomic and Molecular Pathways in Human Acute Monocytic Leukemia Cells

  2020cites this paper
• Condensational particle growth device for reliable cell exposure at the air–liquid interface to nanoparticles

  2019cites this paper
• Alternative approaches for acute inhalation toxicity testing to address global regulatory and non-regulatory data requirements: An international workshop report.

  2018cites this paper
• Review: Endogenously Produced Volatiles for In Vitro Toxicity Testing Using Cell Lines

  2018cites this paper
• Regulating temperature and relative humidity in air-liquid interface in vitro systems eliminates cytotoxicity resulting from control air exposures.

  2017cites this paper
• Air Pollution and Other Environmental Modulators of Cardiac Function.

  2017cites this paper
• A Novel Exposure System Termed NAVETTA for In Vitro Laminar Flow Electrodeposition of Nanoaerosol and Evaluation of Immune Effects in Human Lung Reporter Cells.

  2017cites this paper
• Metabolic Profiling as Well as Stable Isotope Assisted Metabolic and Proteomic Analysis of RAW 264.7 Macrophages Exposed to Ship Engine Aerosol Emissions: Different Effects of Heavy Fuel Oil and Refined Diesel Fuel

  2016cites this paper
• NANOPARTICLE DEPOSITION AND DOSIMETRY FOR IN VITRO TOXICOLOGY

  2015cites this paper
• Particulate Matter from Both Heavy Fuel Oil and Diesel Fuel Shipping Emissions Show Strong Biological Effects on Human Lung Cells at Realistic and Comparable In Vitro Exposure Conditions

  2015cites this paper
• In vitro particulate matter exposure causes direct and lung-mediated indirect effects on cardiomyocyte function.

  2015cites this paper
• Polyhexamethylene guanidine phosphate aerosol particles induce pulmonary inflammatory and fibrotic responses

  2015cites this paper
• Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies.

  2015cites this paper
• Altered protein expression profile associated with phenotypic changes in lung fibroblasts co-cultured with gold nanoparticle-treated small airway epithelial cells.

  2015cites this paper
• Simulations of submicron aerosol deposition at an air–liquid interface for in vitro toxicology

  2015cites this paper
• Optimization of the VITROCELL® Exposure System for In Vitro Toxicity Testing of Diesel Emissions at the Air-Liquid Interface

  2015cites this paper
• Toxicity Screening of Wood Combustion Fine Dust Using a Microbial Test Battery

  2014cites this paper
• Characterization of indoor dust from Brazil and evaluation of the cytotoxicity in A549 lung cells

  2014cites this paper
• Silica nanoparticles are less toxic to human lung cells when deposited at the air–liquid interface compared to conventional submerged exposure

  2014cites this paper
• Utilizing Nanosensor-Incorporated Scaffolds in the Development of a 3D Lung Model

  2014cites this paper
• TOXICOLOGICAL CHARACTERIZATION OF PARTICULATE MATTER FROM WOOD COMBUSTION

  2013cites this paper
• Cellular Dose of Partly Soluble Cu Particle Aerosols at the Air–Liquid Interface Using an In Vitro Lung Cell Exposure System

  2013influential citation
• bronchial epithelium from human smokers cigarette smoke at the air-liquid interface resemble Human bronchial epithelial cells exposed in vitro to

  2013cites this paper
• Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.

  2013cites this paper
• Inflammatory and Oxidative Stress Responses of an Alveolar Epithelial Cell Line to Airborne Zinc Oxide Nanoparticles at the Air-Liquid Interface: A Comparison with Conventional, Submerged Cell-Culture Conditions

  2013cites this paper
• The CULTEX RFS: A Comprehensive Technical Approach for the In Vitro Exposure of Airway Epithelial Cells to the Particulate Matter at the Air-Liquid Interface

  2013cites this paper
• Interaction and Localization of Synthetic Nanoparticles in Healthy and Cystic Fibrosis Airway Epithelial Cells: Effect of Ozone Exposure

  2012cites this paper
• New Perspectives for in Vitro Risk Assessment of Multiwalled Carbon Nanotubes: Application of Coculture and Bioinformatics

  2012cites this paper
• Anti-oxidative and inflammatory responses induced by fly ash particles and carbon black in lung epithelial cells

  2011influential citation
• Regulation of the arachidonic acid mobilization in macrophages by combustion-derived particles

  2011influential citation
• The atmosphere as a colloid system

  2011cites this paper
• Nanomaterial cell interactions: are current in vitro tests reliable?

  2011cites this paper
• Alternatives for Lung Research: Stuck between a Rat and a Hard Place

  2011cites this paper
• A new Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) to evaluate pulmonary drug absorption for metered dose dry powder formulations.

  2011cites this paper
• In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung - A dialog between aerosol science and biology

  2011cites this paper
• Internal benchmarking of a human blood-brain barrier cell model for screening of nanoparticle uptake and transcytosis.

  2011cites this paper
• Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures

  2011cites this paper
• Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative

  2010cites this paper
• Exposure of aerosols and nanoparticle dispersions to in vitro cell cultures: A review on the dose relevance of size, mass, surface and concentration

  2010cites this paper
• Pharmaceutical aerosol deposition device on cell cultures (PADDOCC) : development of an in vitro test system based on pulmonary epithelial cells

  2010cites this paper
• ResearchAllergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein

  2010cites this paper
• Toxicological evaluation of diesel emissions on A549 cells.

  2010cites this paper
• The Pharmaceutical Aerosol Deposition Device on Cell Cultures (PADDOCC) In Vitro System: Design and Experimental Protocol

  2010cites this paper
• Allergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein D

  2010cites this paper
• In vitro micronucleus assay for cigarette smoke using a whole smoke exposure system: a comparison of smoking regimens.

  2010cites this paper
• Lung toxicity determination by in vitro exposure at the air liquid interface with an integrated online dose measurement

  2009cites this paper
• Transplacental transport of nanomaterials.

  2009cites this paper
• Direct particle-to-cell deposition of coarse ambient particulate matter increases the production of inflammatory mediators from cultured human airway epithelial cells.

  2009cites this paper
• In Vitro Testing of Inhalable Fly Ash at the Air Liquid Interface

  2008cites this paper
• In Vitro Exposure Systems and Bioassays for the Assessment of Toxicity of Nanoparticles to the Human Lung

  2008cites this paper