Identification of an alternate splice form of tapasin in human melanoma.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Human Immunology

• Publication date

  2010-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.humimm.2010.05.019PMID 20600451PMCID PMC2952442
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential contribution of TAP and tapasin to HLA class I antigen expression

  2008influential reference
• Tapasin Increases Efficiency of MHC I Assembly in the Endoplasmic Reticulum but Does Not Affect MHC I Stability at the Cell Surface1

  2007cited by this paper
• Selective loading of high-affinity peptides onto major histocompatibility complex class I molecules by the tapasin-ERp57 heterodimer

  2007cited by this paper
• A method to generate antigen-specific mAb capable of staining formalin-fixed, paraffin-embedded tissue sections.

  2005cited by this paper
• A Charged Amino Acid Residue in the Transmembrane/Cytoplasmic Region of Tapasin Influences MHC Class I Assembly and Maturation1

  2005cited by this paper
• An epitope common to HLA class I and class II antigens, Ig light chains, and β2-microglobulin

  2004cited by this paper
• Tapasin enhances MHC class I peptide presentation according to peptide half-life.

  2004cited by this paper
• Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA

  2004cited by this paper
• The monoclonal antibody CR11-351 discriminates HLA-A2 variants identified by T cells

  2004cited by this paper
• Bap29/31 Influences the Intracellular Traffic of MHC Class I Molecules1

  2004cited by this paper
• Endoplasmic reticulum chaperone-specific monoclonal antibodies for flow cytometry and immunohistochemical staining.

  2003cited by this paper
• Association of tapasin and HLA class I antigen down-regulation in primary maxillary sinus squamous cell carcinoma lesions with reduced survival of patients.

  2003cited by this paper
• An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope

  2003cited by this paper
• Tapasin Is a Facilitator, Not an Editor, of Class I MHC Peptide Binding 1

  2003cited by this paper
• Regulation of the expression of mouse TAP-associated glycoprotein (tapasin) by cytokines.

  2002cited by this paper
• The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8–9 residues

  2002cited by this paper
• Direct observation of ligand recognition by T cells

  2002cited by this paper
• Disulfide bond isomerization and the assembly of MHC class I-peptide complexes.

  2002cited by this paper
• Recruitment of MHC Class I Molecules by Tapasin into the Transporter Associated with Antigen Processing-Associated Complex Is Essential for Optimal Peptide Loading

  2002cited by this paper
• Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines.

  2001cited by this paper
• Major Histocompatibility Complex Class I-presented Antigenic Peptides Are Degraded in Cytosolic Extracts Primarily by Thimet Oligopeptidase*

  2001cited by this paper
• A Role for Calnexin in the Assembly of the MHC Class I Loading Complex in the Endoplasmic Reticulum1

  2001cited by this paper
• Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

  2000cited by this paper
• Impaired assembly yet normal trafficking of MHC class I molecules in Tapasin mutant mice.

  2000cited by this paper
• Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression.

  1999cited by this paper
• The N‐terminal region of tapasin is required to stabilize the MHC class I loading complex

  1999cited by this paper
• Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an In vitro melanoma model

  1999cited by this paper
• The thiol oxidoreductase ERp57 is a component of the MHC class I peptide-loading complex.

  1998cited by this paper
• HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading.

  1998cited by this paper
• ER‐60, a chaperone with thiol‐dependent reductase activity involved in MHC class I assembly

  1998cited by this paper
• Soluble tapasin restores MHC class I expression and function in the tapasin-negative cell line .220.

  1998cited by this paper
• Elucidation of the genetic basis of the antigen presentation defects in the mutant cell line .220 reveals polymorphism and alternative splicing of the tapasin gene

  1998cited by this paper
• Cloning and functional characterization of a subunit of the transporter associated with antigen processing.

  1997cited by this paper
• Prominence of beta 2-microglobulin, class I heavy chain conformation, and tapasin in the interactions of class I heavy chain with calreticulin and the transporter associated with antigen processing.

  1997cited by this paper
• Structural Analysis of the Human BIN1 Gene

  1997cited by this paper
• A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes.

  1997influential reference
• Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP.

  1996cited by this paper
• Loss of HLA class I antigens by melanoma cells: molecular mechanisms, functional significance and clinical relevance.

  1995cited by this paper
• Dependence of Peptide Binding by MHC Class I Molecules on Their Interaction with TAP

  1995cited by this paper
• MHC class l/β2-microglobulin complexes associate with TAP transporters before peptide binding

  1994cited by this paper
• Interaction of MHC class I molecules with the transporter associated with antigen processing.

  1994cited by this paper
• Loss of HLA haplotype and B locus down-regulation in melanoma cell lines.

  1994cited by this paper
• MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding.

  1994cited by this paper
• TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective.

  1993cited by this paper
• Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner.

  1993cited by this paper
• Natural history of HLA expression during tumour development.

  1993cited by this paper
• Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2- microglobulin and peptide

  1992cited by this paper
• Peptide binding to class I MHC on living cells and quantitation of complexes required for CTL lysis

  1991cited by this paper
• Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility molecules

  1991cited by this paper
• Lysis of human melanoma cells by autologous cytolytic T cell clones. Identification of human histocompatibility leukocyte antigen A2 as a restriction element for three different antigens

  1989cited by this paper
• A monoclonal antibody directed against the HLA-Bw6 epitope.

  1982cited by this paper

• The Antigen-Processing Pathway via Major Histocompatibility Complex I as a New Perspective in the Diagnosis and Treatment of Endometriosis

  2024cites this paper
• Antigen presentation in vertebrates: Structural and functional aspects.

  2023cites this paper
• Cancer Neoantigens: Challenges and Future Directions for Prediction, Prioritization, and Validation

  2022cites this paper
• Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery

  2021cites this paper
• An Introduction to CAR Immunotherapy

  2020cites this paper
• Innate and Adaptive Immune Responses to Cancer

  2019cites this paper
• Tapasin's protein interactions in the rainbow trout peptide‐loading complex

  2018cites this paper
• Structural bases for MHC class I peptide selection and neoepitope formation

  2018cites this paper
• Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen-specific CTL recognition

  2017cites this paper
• Molecular mechanisms of HLA class I‐mediated immune evasion of human tumors and their role in resistance to immunotherapies

  2016cites this paper
• A New Mode of Cytotoxic T Lymphocyte Induction Secondary to Alteration of the Peptide/Major Histocompatibility Complex Class I Repertoire by Antigen Processing Defects

  2015cites this paper
• Wirkung des humanen Cytomegalovirus auf Transkription und Spleißregulation des MHC-kodierten Chaperons Tapasin

  2015cites this paper
• Expression of tapasin in rainbow trout tissues and cell lines and up regulation in a monocyte/macrophage cell line (RTS11) by a viral mimic and viral infection.

  2014cites this paper
• TAPBPR isoforms exhibit altered association with MHC class I

  2014cites this paper
• Innate and Adaptive Immune Responses to Cancer

  2014cites this paper
• A Functional Study of the Major Histocompatibility Class I Antigen Presentation Pathway in Rainbow Trout (Oncorhynchus mykiss)

  2014cites this paper
• A natural tapasin isoform lacking exon 3 modifies peptide loading complex function

  2013cites this paper
• GILT: Shaping the MHC Class II-Restricted Peptidome and CD4+ T Cell-Mediated Immunity

  2013cites this paper
• Productive association between MHC class I and tapasin requires the tapasin transmembrane/cytosolic region and the tapasin C-terminal Ig-like domain.

  2012cites this paper
• Disulfide Reduction in the Endocytic Pathway: Immunological Functions of Gamma-Interferon-Inducible Lysosomal Thiol Reductase

  2011cites this paper