Adenovirus-mediated viral interleukin-10 gene transfer prevents concanavalin A-induced liver injury.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Digestive and Liver Disease

• Publication date

  2012-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.dld.2011.11.013PMID 22209949
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2008cited by this paper
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  2006cited by this paper
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  2006influential reference
• Viral IL-10-mediated immune regulation in pancreatic islet transplantation.

  2005cited by this paper
• Tetracycline-Inducible Viral Interleukin-10 Intraocular Gene Transfer, Using Adeno-Associated Virus in Experimental Autoimmune Uveoretinitis

  2005cited by this paper
• T cell immunity in autoimmune hepatitis.

  2005cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
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  2002cited by this paper
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  2001cited by this paper
• Involvement of IL-10, an anti-inflammatory cytokine in murine liver injury induced by Concanavalin A.

  2001cited by this paper
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  2000cited by this paper
• Essential pathogenetic role for interferon (IFN-)gamma in concanavalin A-induced T cell-dependent hepatitis: exacerbation by exogenous IFN-gamma and prevention by IFN-gamma receptor-immunoglobulin fusion protein.

  2000cited by this paper
• A Single Amino Acid Determines the Immunostimulatory Activity of Interleukin 10

  2000cited by this paper
• Concanavalin A-induced hepatitis in mice is prevented by interleukin (IL)-10 and exacerbated by endogenous IL-10 deficiency.

  1999cited by this paper
• T Cell Enrichment By Nonadherence to Nylon

  1999cited by this paper
• Activation of transgene expression by early region 4 is responsible for a high level of persistent transgene expression from adenovirus vectors in vivo

  1997cited by this paper
• Requirement of IL-4 and liver NK1+ T cells for concanavalin A-induced hepatic injury in mice.

  1997cited by this paper
• Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy

  1996cited by this paper
• Soluble CD23 and interleukin-4 levels in autoimmune chronic active hepatitis and systemic lupus erythematosus.

  1994cited by this paper
• Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

  1991cited by this paper
• Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1.

  1990cited by this paper
• T cell receptor gene rearrangements of T lymphocytes infiltrating the liver in chronic active hepatitis B and primary biliary cirrhosis (PBC): Oligoclonality of PBC‐derived T cell clones

  1990cited by this paper

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  2021cites this paper
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  2019cites this paper
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  2017cites this paper
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  2016influential citation
• IL-38 alleviates concanavalin A-induced liver injury in mice.

  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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