Basic FGF and IGF-I promote differentiation of human SH-SY5Y neuroblastoma cells in culture.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Growth Factors

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3109/08977199409019601PMID 7514011
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human GAP-43 Gene Expression: Multiple Start Sites for Initiation of Transcription in Differentiating Human Neuroblastoma Cells.

  1993cited by this paper
• Neuronal differentiation triggered by blocking cell proliferation.

  1992cited by this paper
• A complex consisting of pp60c-src/pp60c-srcN and a 38 kDa protein is highly enriched in growth cones from differentiated SH-SY5Y neuroblastoma cells.

  1992cited by this paper
• Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C.

  1992cited by this paper
• Growth factor signaling by receptor tyrosine kinases.

  1992cited by this paper
• Platelet-derived growth factor potentiates phorbol ester-induced neuronal differentiation of human neuroblastoma cells.

  1992cited by this paper
• Protein kinase C remains functionally active during TPA induced neuronal differentiation of SH‐SY5Y human neuroblastoma cells

  1992cited by this paper
• Insulin-like growth factor I shifts from promoting cell division to potentiating maturation during neuronal differentiation.

  1991cited by this paper
• The trk proto-oncogene product: a signal transducing receptor for nerve growth factor.

  1991cited by this paper
• Early activation of endogenous pp60src kinase activity during neuronal differentiation of cultured human neuroblastoma cells

  1990cited by this paper
• Signal transduction by receptors with tyrosine kinase activity.

  1990cited by this paper
• Control of cell fate in a vertebrate neurogenic lineage.

  1990cited by this paper
• A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF.

  1990cited by this paper
• Mitogenically uncoupled insulin and IGF-I receptors of differentiated human neuroblastoma cells are functional and mediate ligand-induced signals.

  1990cited by this paper
• Evaluation of different hybridization procedures for the detection of mycoplasma contamination in cell cultures.

  1990cited by this paper
• Divergent changes of chromogranin A/secretogranin II levels in differentiating human neuroblastoma cells

  1990cited by this paper
• Analysis of nerve growth factor receptor expression in human neuroblastoma and neuroepithelioma cell lines.

  1989cited by this paper
• Insulin and insulinlike growth factor receptors regulating neurite formation in cultured human neuroblastoma cells

  1988cited by this paper
• Purification of a phosphoprotein from rat brain closely related to the 80 kDa substrate of protein kinase C identified in Swiss 3T3 fibroblasts

  1988cited by this paper
• Phenotypic differentiation of aphidicolin-selected human neuroblastoma cultures after long-term exposure to nerve growth factor.

  1987cited by this paper
• Different regulation of N- and c-myc expression during phorbol ester-induced maturation of human SH-SY5Y neuroblastoma cells.

  1987cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Development of a neural phenotype in differentiating ganglion cell‐derived human neuroblastoma cells

  1986cited by this paper
• Characterization, sequence, and expression of the cloned human neuropeptide Y gene.

  1986cited by this paper
• c‐myc and c‐fos expression in differentiating mouse primary keratinocytes.

  1986cited by this paper
• Transcriptional and posttranscriptional control of c-myc during myogenesis: its mRNA remains inducible in differentiated cells and does not suppress the differentiated phenotype

  1986cited by this paper
• Mitogenic response of human SH-SY5Y neuroblastoma cells to insulin-like growth factor I and II is dependent on the stage of differentiation

  1986cited by this paper
• Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene.

  1985cited by this paper
• Effects of insulin, insulin-like growth factor-II and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells.

  1984cited by this paper
• Three human transforming genes are related to the viral ras oncogenes.

  1983cited by this paper
• Kinetics and concentration effects of TPA-induced differentiation of cultured human neuroblastoma cells.

  1983cited by this paper
• Phenotypic changes of human neuroblastoma cells in culture induced by 12‐O‐tetradecanoyl‐phorbol‐13‐acetate

  1981cited by this paper
• Multiple neurotransmitter synthesis by human neuroblastoma cell lines and clones.

  1978cited by this paper
• Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

  1973cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Neural growth patterns: how random and aligned fibers guide 3D cell organization and pseudospheroid formation

  2025cites this paper
• Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson’s disease models

  2024cites this paper
• Effect of Differently Polarized Human Macrophages on the SH-SY5Y Cells Damaged by Ischemia and Hypoxia In Vitro

  2023cites this paper
• Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16

  2021cites this paper
• A Neuroprotective Bovine Colostrum Attenuates Apoptosis in Dexamethasone-Treated MC3T3-E1 Osteoblastic Cells

  2021cites this paper
• РАСТВОРИМЫХ ФАКТОРОВ МАКРОФАГОВ М2-ФЕНОТИПА НА ДИФФЕРЕНЦИРОВКУ КЛЕТОК ЛИНИИ

  2021cites this paper
• Transcription factor activating protein 4 is synthetically lethal and a master regulator of MYCN-amplified neuroblastoma

  2018cites this paper
• A small peptide derived from BMP‐9 can increase the effect of bFGF and NGF on SH‐SY5Y cells differentiation

  2018cites this paper
• S-nitrosylation of the IGF-1 receptor disrupts the cell proliferative action of IGF-1.

  2017cites this paper
• FGF1 protects neuroblastoma SH-SY5Y cells from p53-dependent apoptosis through an intracrine pathway regulated by FGF1 phosphorylation

  2017cites this paper
• IGF-2/IGF-1R signaling has distinct effects on Sox1, Irx3, and Six3 expressions during ES cell derived-neuroectoderm development in vitro

  2016cites this paper
• Etude de la voie d’action intracrine et nucléaire du Fibroblast Growth Factor 1 dans des cellules de type neuronal

  2016influential citation
• Ellagic acid induces a dose- and time-dependent depolarization of mitochondria and activation of caspase-9 and -3 in human neuroblastoma cells.

  2014cites this paper
• Stromal heparan sulfate differentiates neuroblasts to suppress neuroblastoma growth.

  2014cites this paper
• Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma.

  2013cites this paper
• Effects of ellagic acid in human neuroblastoma cells

  2013influential citation
• γ-Enolase C-terminal peptide promotes cell survival and neurite outgrowth by activation of the PI3K/Akt and MAPK/ERK signalling pathways.

  2012cites this paper
• Multiple protein kinases determine the phosphorylated state of the small heat shock protein, HSP27, in SH-SY5Y neuroblastoma cells.

  2011influential citation
• SH-SY5Y human neuroblastoma cell line: in vitro cell model of dopaminergic neurons in Parkinson's disease.

  2010cites this paper
• EFEITO DA CURCUMINA, UM INIBIDOR DO FATOR DE TRANSCRIÇÃO NFκB, SOBRE A VIABILIDADE DE NEUROBLASTOMA SH-SY5Y HUMANO DIFERENCIADO E INDIFERENCIADO, QUANDO DESAFIADO POR PERÓXIDO DE HIDROGÊNIO

  2010cites this paper
• Differentiation induced by physiological and pharmacological stimuli leads to increased antigenicity of human neuroblastoma cells

  2008cites this paper
• Expression of the repressor element-1 silencing transcription factor (REST) is regulated by IGF-I and PKC in human neuroblastoma cells

  2008cites this paper
• Disialoganglioside GD3 synthase expression recruits membrane transglutaminase 2 during erythroid differentiation of the human chronic myelogenous leukemia K562 cells

  2008cites this paper
• Insulin, IGF-1, and muscarinic agonists modulate schizophrenia-associated genes in human neuroblastoma cells.

  2008cites this paper
• IGF signaling as a therapeutic target in pediatric solid tumors of the central and peripheral nervous system

  2007cites this paper
• Running exercise- and antidepressant-induced increases in growth and survival-associated signaling molecules are IGF-dependent

  2007cites this paper
• Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation.

  2007cites this paper
• Characterization of novel splice variants of the PAC1 receptor in human neuroblastoma cells: consequences for signaling by VIP and PACAP.

  2006cites this paper
• Effects of thimerosal on NGF signal transduction and cell death in neuroblastoma cells.

  2005cites this paper
• Protein Kinase C-# { 128 } Is Implicated in Neurite Outgrowth in Differentiating Human Neuroblastoma Cells ’

  2005cites this paper
• The insulin-like growth factor system and its pleiotropic functions in brain.

  2005cites this paper
• Fibroblast growth factor‐2 over‐rides insulin‐like growth factor‐I induced proliferation and cell survival in human neuroblastoma cells

  2004cites this paper
• Insulin-like growth factor-I receptor and estrogen receptor crosstalk mediates hormone-induced neurite outgrowth in PC12 cells.

  2004cites this paper
• Antiapoptotic effects of leptin in human neuroblastoma cells.

  2004cites this paper
• Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior.

  2004cites this paper
• The Adenosine Receptor and Serum Deprivation-Induced Neuronal Differentiation

  2004cites this paper
• Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation

  2004cites this paper
• L- and D-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) inhibit neurite outgrowth from SH-SY5Y cells.

  2002cites this paper
• IGFs and IGF-binding proteins as diagnostic markers and biological modulators in brain tumors

  2002cites this paper
• Insulin-like growth factor-I protects neuroblastoma against starvation-induced apoptosis and is associated with increased Bcl-2 expression.

  2002cites this paper
• Activation of the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway by Retinoic Acid Is Required for Neural Differentiation of SH-SY5Y Human Neuroblastoma Cells*

  2002cites this paper
• VEGF is upregulated in a neuroblastoma and hepatocyte coculture model.

  2001cites this paper
• Regulation of chromogranin biosynthesis by neurotrophic growth factors in neuroblastoma cells.

  2001cites this paper
• A functional role for ERK in gene induction, but not in neurite outgrowth in differentiating neuroblastoma cells.

  2001cites this paper
• Regulation and function of the Mad/Max/Myc network during neuronal and hematopoietic differentiation.

  2001cites this paper
• TrkA signal transduction pathways in neuroblastoma.

  2001cites this paper
• Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF.

  2001cites this paper
• Retinoic acid-induced changes in polysialyltransferase mRNA expression and NCAM polysialylation in human neuroblastoma cells.

  2001cites this paper
• Retinoic acid‐induced changes in polysialyltransferase mRNA expression and NCAM polysialylation in human neuroblastoma cells

  2001cites this paper
• Differences in early and late responses between neurotrophin-stimulated trkA- and trkC-transfected SH-SY5Y neuroblastoma cells.

  2001cites this paper
• Prognostic and Biological Role of Neurotrophin- Receptor TrkA and TrkB in Neuroblastoma1

  2000cites this paper
• The effects of serum depletion and dexamethasone on growth and differentiation of human neuroblastoma cell lines.

  2000cites this paper
• Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells

  2000cites this paper
• Insulin‐like growth factor I is the key growth factor in serum that protects neuroblastoma cells from hyperosmotic‐induced apoptosis

  2000cites this paper
• Arsenic trioxide inhibits neuroblastoma growth in vivo and promotes apoptotic cell death in vitro.

  2000cites this paper
• Insulin-like growth factor-I-dependent signal transduction pathways leading to the induction of cell growth and differentiation of human neuroblastoma cell line SH-SY5Y: the roles of MAP kinase pathway and PI 3-kinase pathway.

  2000cites this paper
• Sequential Treatment of SH‐SY5Y Cells with Retinoic Acid and Brain‐Derived Neurotrophic Factor Gives Rise to Fully Differentiated, Neurotrophic Factor‐Dependent, Human Neuron‐Like Cells

  2000cites this paper
• Activation and protein kinase C-dependent nuclear accumulation of ERK in differentiating human neuroblastoma cells.

  2000cites this paper
• Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins

  2000cites this paper
• Ras-MAPK Signaling in Differentiating SH-SY5Y Human Neuroblastoma Cells

  2000cites this paper
• Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells

  1999cites this paper
• Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells.

  1999cites this paper
• BCL-2 is upregulated in human SH-SY5Y neuroblastoma cells differentiated by overexpression of fibroblast growth factor 1.

  1999cites this paper
• Insulin-like-growth-factor-I (IGF-I) antagonizes apoptosis induced by serum deficiency and doxorubicin in neuronal cell culture.

  1999cites this paper
• Extracellular‐Regulated Kinases and Phosphatidylinositol 3‐Kinase Are Involved in Brain‐Derived Neurotrophic Factor‐Mediated Survival and neuritogenesis of the Neuroblastoma Cell Line SH‐SY5Y

  1999cites this paper
• Variation Among Cell Types in the Signaling Pathways by which IGF-I Stimulates Specific Cellular Responses*

  1999cites this paper
• PKCε, Via its Regulatory Domain and Independently of its Catalytic Domain, Induces Neurite-like Processes in Neuroblastoma Cells

  1999cites this paper
• Protein Kinase C-dependent Tyrosine Phosphorylation of p130 cas in Differentiating Neuroblastoma Cells*

  1998cites this paper
• Differential Regulation of Focal Adhesion Kinase and Mitogen‐Activated Protein Kinase Tyrosine Phosphorylation During Insulin‐Like Growth Factor‐I‐Mediated Cytoskeletal Reorganization

  1998cites this paper
• Activated Transcription of the Human Neuropeptide Y Gene in Differentiating SH‐SY5Y Neuroblastoma Cells Is Dependent on Transcription Factors AP‐1, AP‐2α, and NGFI

  1998cites this paper
• Bidirectional Regulation of p38 Kinase and c-Jun N-terminal Protein Kinase by Insulin-like Growth Factor-I*

  1998cites this paper
• An ataxia telangiectasia model: inefficient cell differentiation and possible reversal by serine protease inhibitors, tumor necrosis factor inhibitors, dexamethasone, and glutathione enhancers.

  1998cites this paper
• Gangliosides inhibit growth factor‐stimulated neurite outgrowth in SH‐SY5Y human neuroblastoma cells

  1997cites this paper
• Tyrosine Phosphorylation of Paxillin and Focal Adhesion Kinase during Insulin-like Growth Factor-I-stimulated Lamellipodial Advance*

  1997cites this paper
• Insulin-like Growth Factor-I-mediated Neurite Outgrowth in Vitro Requires Mitogen-activated Protein Kinase Activation*

  1997cites this paper
• The differential effects of 12-O-tetradecanoylphorbol-13-acetate on the gap junctions and connexins of the developing mammalian lens.

  1997cites this paper
• Emploi thérapeutique de l'IGF-I dans le traitement de maladies neurodégénératives.

  1997cites this paper
• Protein kinase C-epsilon is implicated in neurite outgrowth in differentiating human neuroblastoma cells.

  1996cites this paper
• Modulation by retinoic acid of insulin-like growth factor (IGF) and IGF binding protein expression in human SK-N-SH neuroblastoma cells.

  1996cites this paper
• Effects of γ-IFN and NGF on subpopulations in a human neuroblastoma cell line: Flow cytometric and morphological analysis

  1996cites this paper
• Transfection of TRK-A into human neuroblastoma cells restores their ability to differentiate in response to nerve growth factor.

  1995cites this paper
• Differentiation and survival influences of growth factors in human neuroblastoma.

  1995cites this paper
• Protein kinase C‐α and ‐ε are enriched in growth cones of differentiating SH‐SY5Y human neuroblastoma cells

  1995cites this paper