Clinical and biological significance of precursor lesions of intrahepatic cholangiocarcinoma.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  World Journal of Hepatology

• Publication date

  2015-11-08

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4254/wjh.v7.i25.2563PMID 26557948PMCID PMC4635141
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Biliary adenofibroma with malignant transformation and pulmonary metastases: CT findings.

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• Genetic alterations in hepatocellular carcinoma and intrahepatic cholangiocarcinoma.

  2001cited by this paper
• Microsatellite instability and alternative genetic pathway in intrahepatic cholangiocarcinoma.

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  2000cited by this paper
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  1999cited by this paper
• Von Meyenburg complexes of the liver: imaging findings.

  1998cited by this paper
• Monosomy 22 in a case of biliary adenofibroma.

  1997cited by this paper
• The so-called bile duct adenoma is a peribiliary gland hamartoma.

  1996cited by this paper
• The hepatic von Meyenburg complex: prevalence and association with hepatic and renal cysts among 2843 autopsies [corrected].

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• Cholangiocarcinoma arising in bile duct adenoma with focal area of bile duct hamartoma

  1995cited by this paper
• Biliary adenofibroma. A heretofore unrecognized benign biliary tumor of the liver.

  1993cited by this paper
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  1990cited by this paper
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  1988cited by this paper
• Bile duct adenomas as liver nodules.

  1978cited by this paper
• [Benign and malignant tumors of the liver].

  1963cited by this paper
• Benign and Malignant Tumors of the Liver

  1959cited by this paper

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