Circulating osteocrin stimulates bone growth by limiting C-type natriuretic peptide clearance

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Clinical Investigation

• Publication date

  2017-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1172/JCI94912PMID 28990933PMCID PMC5663354
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelium-Derived C-Type Natriuretic Peptide Contributes to Blood Pressure Regulation by Maintaining Endothelial Integrity

  2017cited by this paper
• Mutations in C-natriuretic peptide (NPPC): a novel cause of autosomal dominant short stature

  2017cited by this paper
• C-type natriuretic peptide restores impaired skeletal growth in a murine model of glucocorticoid-induced growth retardation.

  2016cited by this paper
• Heterozygous Mutations in Natriuretic Peptide Receptor‐B (NPR2) Gene as a Cause of Short Stature

  2015cited by this paper
• The Local CNP/GC-B system in growth plate is responsible for physiological endochondral bone growth

  2015cited by this paper
• Nosology and classification of genetic skeletal disorders: 2015 revision

  2015cited by this paper
• Heterozygous NPR2 Mutations Cause Disproportionate Short Stature, Similar to Léri-Weill Dyschondrosteosis.

  2015cited by this paper
• Bone development.

  2015cited by this paper
• Direct chemiluminescent enzyme immunoassay for atrial natriuretic peptide in mammalian plasma using a PEGylated antibody.

  2014cited by this paper
• Identification and functional characterization of two novel NPR2 mutations in Japanese patients with short stature.

  2014cited by this paper
• Overgrowth syndrome associated with a gain‐of‐function mutation of the natriuretic peptide receptor 2 (NPR2) gene

  2014cited by this paper
• Heterozygous mutations in natriuretic peptide receptor-B (NPR2) gene as a cause of short stature in patients initially classified as idiopathic short stature.

  2013cited by this paper
• Importance of Suitable Reference Gene Selection for Quantitative RT-PCR during ATDC5 Cells Chondrocyte Differentiation

  2013cited by this paper
• An Overgrowth Disorder Associated with Excessive Production of cGMP Due to a Gain-of-Function Mutation of the Natriuretic Peptide Receptor 2 Gene

  2012cited by this paper
• Competitive binding of musclin to natriuretic peptide receptor 3 with atrial natriuretic peptide.

  2009cited by this paper
• Chronically elevated plasma C-type natriuretic peptide level stimulates skeletal growth in transgenic mice.

  2009cited by this paper
• Osteocrin Is a Specific Ligand of the Natriuretic Peptide Clearance Receptor That Modulates Bone Growth*

  2007cited by this paper
• Intact kinase homology domain of natriuretic peptide receptor-B is essential for skeletal development.

  2007cited by this paper
• Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature.

  2006cited by this paper
• A Loss-of-Function Mutation in Natriuretic Peptide Receptor 2 (Npr2) Gene Is Responsible for Disproportionate Dwarfism in cn/cn Mouse*

  2005cited by this paper
• Critical roles of the guanylyl cyclase B receptor in endochondral ossification and development of female reproductive organs.

  2004cited by this paper
• Musclin, a Novel Skeletal Muscle-derived Secretory Factor*

  2004cited by this paper
• Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway

  2004cited by this paper
• Mutations in the transmembrane natriuretic peptide receptor NPR-B impair skeletal growth and cause acromesomelic dysplasia, type Maroteaux.

  2004cited by this paper
• Developmental regulation of the growth plate

  2003cited by this paper
• Osteocrin, a Novel Bone-specific Secreted Protein That Modulates the Osteoblast Phenotype*

  2003cited by this paper
• Dwarfism and early death in mice lacking C-type natriuretic peptide

  2001cited by this paper
• The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.

  1999cited by this paper
• Molecular cloning of the complementary DNA and gene that encode mouse brain natriuretic peptide and generation of transgenic mice that overexpress the brain natriuretic peptide gene.

  1994cited by this paper
• Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver.

  1994cited by this paper
• Molecular biology and biochemistry of the natriuretic peptide system. II: Natriuretic peptide receptors.

  1992cited by this paper

• The role of neprilysin in musculoskeletal diseases.

  2026cites this paper
• Roles of myokines in osteoporosis under physiological and diabetic conditions

  2025cites this paper
• Crosstalk between bone and brain in Alzheimer's disease: Mechanisms, applications, and perspectives

  2024cites this paper
• Neprilysin inhibition promotes skeletal growth via the CNP/NPR-B pathway.

  2024cites this paper
• The role of osteocrin in memory formation during early learning, as revealed by visual imprinting in chicks

  2024cites this paper
• Impact of Propolis Administration on Osteocrin Expression and Osteoblast-to-osteoclast Ratio in the Femurs of Rats Fed a High-fat Diet

  2024cites this paper
• Comparison of perioperative serum osteocrin concentrations between surgical techniques in dogs with cranial cruciate ligament rupture.

  2023cites this paper
• Musclin attenuates lipid deposition in hepatocytes through SIRT7/autophagy-mediated suppression of ER stress.

  2023cites this paper
• Different Effects of Cyclical Ketogenic vs. Nutritionally Balanced Reduction Diet on Serum Concentrations of Myokines in Healthy Young Males Undergoing Combined Resistance/Aerobic Training

  2023cites this paper
• Periosteum: Functional Anatomy and Clinical Application

  2023cites this paper
• NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice

  2023cites this paper
• NPRC deletion attenuates cardiac fibrosis in diabetic mice by activating PKA/PKG and inhibiting TGF-β1/Smad pathways

  2023cites this paper
• Partial prevention of glucocorticoid-induced osteocyte deterioration in young male mice with osteocrin gene therapy

  2022cites this paper
• Guanylyl Cyclase-B Dependent Bone Formation in Mice is Associated with Youth, Increased Osteoblasts, and Decreased Osteoclasts

  2022cites this paper
• Metformin combats high glucose-induced damage to the osteogenic differentiation of human periodontal ligament stem cells via inhibition of the NPR3-mediated MAPK pathway

  2022cites this paper
• Skeletal muscle derived Musclin protects the heart during pathological overload

  2022cites this paper
• Low Circulating Musclin is Associated With Adverse Prognosis in Patients Undergoing Transcatheter Aortic Valve Implantation at Low‐Intermediate Risk

  2022cites this paper
• Loss of Parathyroid Hormone Receptor Signaling in Osteoprogenitors Is Associated With Accumulation of Multiple Hematopoietic Lineages in the Bone Marrow

  2022cites this paper
• Physiological and Pathophysiological Effects of C-Type Natriuretic Peptide on the Heart

  2022cites this paper
• Osteocrin alleviates cardiac hypertrophy via attenuating oxidative stress.

  2022cites this paper
• Circulatory C-type natriuretic peptide reduces mucopolysaccharidosis-associated craniofacial hypoplasia in vivo

  2022cites this paper
• Osteocrin, a bone-derived humoral factor, exerts a renoprotective role in ischemia–reperfusion injury in mice

  2021cites this paper
• Renal Natriuretic Peptide Receptor-C Deficiency Attenuates NaCl Cotransporter Activity in Angiotensin II-Induced Hypertension.

  2021cites this paper
• Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin

  2021cites this paper
• Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dwarfism

  2021cites this paper
• Global transcriptomic analysis of a murine osteocytic cell line subjected to spaceflight

  2021cites this paper
• Disorders of Mineral Metabolism: Normal Homeostasis

  2021cites this paper
• Osteocrin, a novel myokine, prevents diabetic cardiomyopathy via restoring proteasomal activity

  2021cites this paper
• Mechanical load regulates bone growth via periosteal Osteocrin.

  2021cites this paper
• Osteocrin ameliorates adriamycin nephropathy via p38 mitogen-activated protein kinase inhibition

  2021cites this paper
• Partial prevention of glucocorticoid-induced osteocyte deterioration with osteocrin gene therapy

  2021cites this paper
• Molecular and cellular regulation of intramembranous and endochondral bone formation during embryogenesis

  2020cites this paper
• Natriuretic peptides as the basis of peptide drug discovery for cardiovascular diseases.

  2020cites this paper
• Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect

  2020cites this paper
• Myokines mediate the cross talk between skeletal muscle and other organs

  2020cites this paper
• Osteocrin attenuates inflammation, oxidative stress, apoptosis, and cardiac dysfunction in doxorubicin‐induced cardiotoxicity

  2020cites this paper
• Effect of statin therapy on plasma C-type Natriuretic Peptides and Endothelin-1 in males with and without symptomatic coronary artery disease

  2020cites this paper
• Male mice with elevated C-type natriuretic peptide-dependent guanylyl cyclase-B activity have increased osteoblasts, bone mass and bone strength.

  2020cites this paper
• New developments in the management of achondroplasia

  2020cites this paper
• Guanylyl Cyclase-cGMP Signaling Pathway in Melanocytes: Differential Effects of Altered Gravity in Non-Metastatic and Metastatic Cells

  2020cites this paper
• C-type natriuretic peptide restores growth impairment under enzyme replacement in mice with mucopolysaccharidosis VII.

  2020cites this paper
• Periosteum-derived Osteocrin regulates bone growth through both endochondral ossification and intramembranous ossification

  2019cites this paper
• Plasma C-Type Natriuretic Peptide: Emerging Applications in Disorders of Skeletal Growth

  2019cites this paper
• Natriuretic Peptides and Normal Body Fluid Regulation.

  2018cites this paper
• Expression of C-type Natriuretic Peptide and its Specific Guanylyl Cyclase-Coupled Receptor in Pig Ovarian Granulosa Cells

  2018cites this paper
• Exogenous C-type natriuretic peptide restores normal growth and prevents early growth plate closure in its deficient rats

  2018cites this paper
• Profiling of Stem/Progenitor Cell Regulatory Genes of the Synovial Joint by Genome-Wide RNA-Seq Analysis

  2018cites this paper
• A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction

  2018cites this paper