Promotion of Medial Collateral Ligament Healing Using a High-Voltage Electrical Field

Purpose. To assess the biomechanical and histological effects of a high-voltage electrical field on ligament healing. Methods. 54 male Wistar rats were used. The medial collateral ligaments (MCLs) of 6 rats were measured for normal biomechanical failure load and stiffness. MCLs of the remaining 48 rats were transected and randomly assigned; half were subjected to a high-voltage electrical field for 8 hours a day (experimental group), and the other half were kept under normal conditions (control group). Eight rats from each group were killed 2, 4, and 6 weeks after the transection and their MCLs were tested biomechanically and histologically. Results. Failure load and stiffness of the MCLs in the experimental group were significantly higher than those in the control group 2 weeks after transection, but not thereafter. At week 2, the granulation tissue completely occupied the space between the cut ends of the MCL in the experimental group, whereas some gaps remained in the control group. Conclusion. A high-voltage electrical field appear to accelerate ligament healing in the initial 2 weeks. Earlier initial healing may allow earlier start of the rehabilitation.

• Publication year

  2007

• Venue

  Journal of Orthopaedic Surgery

• Publication date

  2007-04-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1177/230949900701500106PMID 17429112
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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