Detection of synchronized burst firing in cultured human induced pluripotent stem cell-derived neurons using a 4-step method.

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2018-03-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bbrc.2018.02.117PMID 29454965
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Temporally coordinated spiking activity of human induced pluripotent stem cell-derived neurons co-cultured with astrocytes.

  2018cited by this paper
• Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias

  2017cited by this paper
• Human induced pluripotent stem cell (hiPSC)-derived neurons respond to convulsant drugs when co-cultured with hiPSC-derived astrocytes.

  2017cited by this paper
• Modeling Drug‐Induced Neuropathy Using Human iPSCs for Predictive Toxicology

  2017cited by this paper
• Functional characterization of GABAA receptor-mediated modulation of cortical neuron network activity in microelectrode array recordings

  2017cited by this paper
• Establishment of a Human Neuronal Network Assessment System by Using a Human Neuron/Astrocyte Co-Culture Derived from Fetal Neural Stem/Progenitor Cells

  2016cited by this paper
• Physiological maturation and drug responses of human induced pluripotent stem cell-derived cortical neuronal networks in long-term culture

  2016cited by this paper
• Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative.

  2016cited by this paper
• A comparison of computational methods for detecting bursts in neuronal spike trains and their application to human stem cell-derived neuronal networks

  2016cited by this paper
• Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

  2014cited by this paper
• Quantitative differences in developmental profiles of spontaneous activity in cortical and hippocampal cultures

  2014cited by this paper
• Parameters for burst detection

  2014cited by this paper
• Long-term electrophysiological activity and pharmacological response of a human induced pluripotent stem cell-derived neuron and astrocyte co-culture.

  2014cited by this paper
• Endogenous cholinergic tone modulates spontaneous network level neuronal activity in primary cortical cultures grown on multi-electrode arrays

  2013cited by this paper
• Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics

  2012cited by this paper
• Detection of bursts and pauses in spike trains.

  2012cited by this paper
• Age-dependent Homeostatic Plasticity of GABAergic Signaling in Developing Retinal Networks

  2011cited by this paper
• Opportunities for Use of Human iPS Cells in Predictive Toxicology

  2011cited by this paper
• Spiking Signatures of Spontaneous Activity Bursts in Hippocampal Cultures

  2011cited by this paper
• A self-adapting approach for the detection of bursts and network bursts in neuronal cultures

  2010cited by this paper
• Detection of bursts in extracellular spike trains using hidden semi-Markov point process models

  2010cited by this paper
• Detection of bursts in neuronal spike trains by the mean inter-spike interval method

  2009cited by this paper
• Methods for characterizing interspike intervals and identifying bursts in neuronal activity.

  2007cited by this paper
• A nonparametric approach for detection of bursts in spike trains.

  2007cited by this paper
• An extremely rich repertoire of bursting patterns during the development of cortical cultures

  2006cited by this paper
• Burst detection algorithms for the analysis of spatio-temporal patterns in cortical networks of neurons

  2005cited by this paper
• Burst and oscillation as disparate neuronal properties.

  1996cited by this paper
• Identification of bursts in spike trains.

  1992cited by this paper
• Bursts and recurrences of bursts in the spike trains of spontaneously active striate cortex neurons.

  1985cited by this paper

• Unravelling the Dynamics of Seizure-Like Activity in Neuronal Networks using Machine Learning.

  2025cites this paper
• Human iPSC-Derived MSCs Induce Neurotrophic Effects and Improve Metabolic Activity in Acute Neuronal Injury Models

  2024cites this paper
• Development of an evaluation method for addictive compounds based on electrical activity of human iPS cell‐derived dopaminergic neurons using microelectrode array

  2024cites this paper
• Exploring Kainic Acid-Induced Alterations in Circular Tripartite Networks with Advanced Analysis Tools

  2024cites this paper
• Calcium-Dependent Hyperexcitability in Human Stem Cell–Derived Rett Syndrome Neuronal Networks

  2024cites this paper
• Neuroprotective Potential of L-Glutamate Transporters in Human Induced Pluripotent Stem Cell-Derived Neural Cells against Excitotoxicity

  2023cites this paper
• [In vitro in vivo extrapolation (IVIVE) in safety pharmacology to improve human predictability -new evaluation systems for new drug modalities].

  2023cites this paper
• Large‐Area Field Potential Imaging Having Single Neuron Resolution Using 236 880 Electrodes CMOS‐MEA Technology

  2023cites this paper
• Hyperexcitability in human MECP2 null neuronal networks manifests as calcium-dependent reverberating super bursts

  2023cites this paper
• Verification of the seizure liability of compounds based on their in vitro functional activity in cultured rat cortical neurons and co-cultured human iPSC-derived neurons with astrocytes and in vivo extrapolation to cerebrospinal fluid concentration.

  2023cites this paper
• An integrated approach for early in vitro seizure prediction utilising hiPSC neurons and human ion channel assays.

  2023cites this paper
• Evaluation of neurotoxicity for pesticide-related compounds in human iPS cell-derived neurons using microelectrode array.

  2023cites this paper
• Raster plots machine learning to predict the seizure liability of drugs and to identify drugs

  2022cites this paper
• Responses to antibiotics in human iPSC-derived neurons based on the clinical antibiotic-associated encephalopathy classification.

  2022cites this paper
• Long-term morphological and functional dynamics of human stem cell-derived neuronal networks on high-density micro-electrode arrays

  2022cites this paper
• Large-area electrical imaging having single neuron resolution using 236,880 electrodes CMOS-MEA technology

  2022cites this paper
• A functional neuron maturation device provides convenient application on microelectrode array for neural network measurement

  2022cites this paper
• Electrophysiological responses to seizurogenic compounds dependent on E/I balance in human iPSC-derived cortical neural networks.

  2021cites this paper
• Principal Component Analysis to Distinguish Seizure Liability of Drugs in Human iPS Cell-Derived Neurons.

  2021cites this paper
• Variant-specific changes in persistent or resurgent sodium current in SCN8A-related epilepsy patient-derived neurons.

  2020cites this paper
• [Strong demands for the new preclinical assessment system of the CNS adverse effects].

  2020cites this paper
• [Evaluation methods for drug-induced seizure by microelectrode array recording using human iPS cell-derived neurons].

  2020cites this paper
• [Approach to drug efficacy and safety assessment based on functions of a human iPSC-derived neuronal network].

  2020cites this paper
• Variant-specific changes in persistent or resurgent Na+ current in SCN8A-EIEE13 iPSC-derived neurons

  2020cites this paper
• Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns

  2020cites this paper
• Can We Panelize Seizure?

  2020cites this paper
• Towards animal-free neurotoxicity screening: Applicability of hiPSC-derived neuronal models for in vitro seizure liability assessment.

  2019cites this paper
• Impact of Sleep–Wake-Associated Neuromodulators and Repetitive Low-Frequency Stimulation on Human iPSC-Derived Neurons

  2019cites this paper
• First observations of spontaneous bursting in human hNT neurons with a customised neural chip platform

  2019cites this paper
• Approach to Neurotoxicity using Human iPSC Neurons: Consortium for Safety Assessment using Human iPS Cells.

  2019cites this paper
• In vitro Models for Seizure-Liability Testing Using Induced Pluripotent Stem Cells

  2018influential citation
• L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks

  2018cites this paper
• Toxicological evaluation of convulsant and anticonvulsant drugs in human induced pluripotent stem cell-derived cortical neuronal networks using an MEA system

  2018cites this paper