Normal cellular and transformation-associated abl proteins share common sites for protein kinase C phosphorylation.

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Molecular and Cellular Biology

• Publication date

  1987-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.7.12.4280PMID 3125421PMCID PMC368110
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL.

  1987cited by this paper
• Protein kinase C directly phosphorylates the insulin receptor in vitro and reduces its protein-tyrosine kinase activity.

  1986cited by this paper
• Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene.

  1986influential reference
• Early signals in the mitogenic response.

  1986cited by this paper
• Alternative 5' exons in c-abl mRNA.

  1986influential reference
• Studies and perspectives of protein kinase C.

  1986cited by this paper
• Distinct structural requirements of Ca2+/phospholipid‐dependent protein kinase (protein kinase C) and cAMP‐dependent protein kinase as evidenced by synthetic peptide substrates

  1985cited by this paper
• Myristic acid, a rare fatty acid, is the lipid attached to the transforming protein of Rous sarcoma virus and its cellular homolog

  1985cited by this paper
• Purification and characterization of a protein-tyrosine kinase encoded by the Abelson murine leukemia virus.

  1985influential reference
• Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein.

  1985cited by this paper
• Studies on the phosphorylation of myelin basic protein by protein kinase C and adenosine 3':5'-monophosphate-dependent protein kinase.

  1985cited by this paper
• Protein kinase C phosphorylates pp60src at a novel site.

  1985cited by this paper
• Isolation and analysis of an Abelson murine leukemia virus-encoded tyrosine-specific kinase produced in Escherichia coli.

  1985cited by this paper
• Substrate specificity of phospholipid/Ca2+-dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein.

  1985cited by this paper
• The human cellular abl gene product in the chronic myelogenous leukemia cell line K562 has an associated tyrosine protein kinase activity.

  1985cited by this paper
• Cell lines and clinical isolates derived from Ph1-positive chronic myelogenous leukemia patients express c-abl proteins with a common structural alteration.

  1985cited by this paper
• Tumor-promoting phorbol diesters cause the phosphorylation of epidermal growth factor receptors in normal human fibroblasts at threonine-654.

  1985influential reference
• Activation of the c-abl oncogene by viral transduction or chromosomal translocation generates altered c-abl proteins with similar in vitro kinase properties

  1985cited by this paper
• Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

  1985cited by this paper
• Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane

  1984influential reference
• Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.

  1984cited by this paper
• The mouse c-abl locus: molecular cloning and characterization.

  1984cited by this paper
• Tumor promoters block tyrosine-specific phosphorylation of the epidermal growth factor receptor.

  1984cited by this paper
• Only site-directed antibodies reactive with the highly conserved src-homologous region of the v-abl protein neutralize kinase activity

  1984cited by this paper
• C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.

  1984cited by this paper
• Diverse mitogenic agents induce the phosphorylation of two related 42,000-dalton proteins on tyrosine in quiescent chick cells

  1984cited by this paper
• Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells.

  1984cited by this paper
• Myristylation of gag-onc fusion proteins in mammalian transforming retroviruses.

  1984cited by this paper
• An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

  1984cited by this paper
• Nucleotide sequences of the Drosophila src and abl homologs: conservation and variability in the src family oncogenes.

  1983cited by this paper
• The human v-abl cellular homologue.

  1983cited by this paper
• Site-directed deletions of Abelson murine leukemia virus define 3' sequences essential for transformation and lethality

  1983cited by this paper
• Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence

  1983cited by this paper
• A tumor promoter stimulates phosphorylation on tyrosine.

  1983cited by this paper
• Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

  1983cited by this paper
• Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.

  1983cited by this paper
• Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine

  1983cited by this paper
• In vivo tyrosine phosphorylations of the Abelson virus transforming protein are absent in its normal cellular homolog.

  1982cited by this paper
• Differential expression of cellular oncogenes during pre- and postnatal development of the mouse

  1982cited by this paper
• Expression of an Abelson murine leukemia virus-encoded protein in Escherichia coli causes extensive phosphorylation of tyrosine residues.

  1982cited by this paper
• Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle

  1982cited by this paper
• Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

  1982influential reference
• The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid.

  1982cited by this paper
• Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine.

  1981cited by this paper
• Lethal effect of the Abelson murine leukemia virus transforming gene product.

  1981cited by this paper
• Genome structure of Abelson murine leukemia virus variants: proviruses in fibroblasts and lymphoid cells

  1981cited by this paper
• Abelson murine leukemia virus mutants with alterations in the virus-specific P120 molecule

  1980cited by this paper
• Abelson murine leukemia virus mutants deficient in kinase activity and lymphoid cell transformation

  1980cited by this paper
• A transformation-defective mutant of Abelson murine leukemia virus lacks protein kinase activity.

  1980cited by this paper
• Abelson murine leukemia virus transformation-defective mutants with impaired P120-associated protein kinase activity

  1980cited by this paper
• Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine

  1980cited by this paper
• Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: studies with cloned viral DNA.

  1980cited by this paper
• Transformation of Immature Lymphoid Cells by Abelson Murine Leukemia Virus

  1979cited by this paper
• A normal cell protein cross-reactive to the major Abelson murine leukaemia virus gene product

  1979cited by this paper
• Identification of an Abelson murine leukemia virus-encoded protein present in transformed fibroblast and lymphoid cells.

  1978cited by this paper
• Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

  1977cited by this paper
• Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome.

  1975cited by this paper
• Direct transformation of 3T3 cells by Abelson murine leukaemia virus

  1975cited by this paper
• In vitro transformation of lymphoid cells by Abelson murine leukemia virus.

  1975cited by this paper
• Karyotypic, virologic, and immunologic analyses of two continuous lymphocyte lines established from New Zealand black mice: possible relationship of chromosomal mosaicism to autoimmunity.

  1972cited by this paper
• Lymphosarcoma: virus-induced thymic-independent disease in mice.

  1970cited by this paper

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  2017cites this paper
• Imaging the Complexity, Plasticity, and Dynamics of Caveolae

  2014cites this paper
• Mitotic Phosphorylation Rescues Abl from F-actin-mediated Inhibition*

  2005cites this paper
• Two different pathways link G-protein-coupled receptors with tyrosine kinases for the modulation of growth and survival in human hematopoietic progenitor cells.

  2005cites this paper
• The Extreme Carboxyl Terminus of v-Abl Is Required for Lymphoid Cell Transformation by Abelson Virus

  2003influential citation
• Inhibition of protein kinase C delta has negative effect on anchorage-independent growth of BCR-ABL-transformed Rat1 cells.

  2001cites this paper
• The molecular effects of oncogenesis on cell-extracellular matrix adhesion (review).

  2001cites this paper
• Molecular Biology of Chronic Myeloid Leukemia

  2001cites this paper
• The Carboxyl Terminus of v-Abl Protein Can Augment SH2 Domain Function

  2000cites this paper
• Effects of bryostatin-1 on chronic myeloid leukaemia-derived haematopoietic progenitors

  1999cites this paper
• Association of TGF-beta signaling in angiotensin II-induced PAI-1 mRNA upregulation in mesangial cells: role of PKC.

  1999cites this paper
• Determination of cell fate by c-Abl activation in the response to DNA damage

  1998cites this paper
• Chronic myelogenous leukemia: molecular and cellular aspects

  1998cites this paper
• Direct Interaction of Jak1 and v-Abl Is Required for v-Abl-Induced Activation of STATs and Proliferation

  1998cites this paper
• The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity.

  1997cites this paper
• The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity

  1997cites this paper
• Ras complements the carboxyl terminus of v-Abl protein in lymphoid transformation

  1996cites this paper
• Protein kinase C and its substrates.

  1996cites this paper
• Protein kinase C and its substrates.

  1996cites this paper
• The cytostatic function of c‐Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products.

  1996cites this paper
• - Abl: c-Abl protein-tyrosine kinase (vertebrates)

  1995cites this paper
• The biology of Abl during hemopoietic stem cell differentiation and development.

  1995cites this paper
• Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity.

  1995cites this paper
• BCR-ABL: an anti-apoptosis gene in chronic myelogenous leukemia.

  1995cites this paper
• Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation.

  1995cites this paper
• The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity [published erratum appears in J Cell Biol 1994 Mar;124(5):865]

  1994cites this paper
• Expression and Function of Protein Kinases During Mammalian Gametogenesis

  1994cites this paper
• Inhibition of phosphorylation of p160 BCR within p210 BCR-ABL complexes during early stages of phorbol ester-induced differentiation of K562 cells.

  1993cites this paper
• 5 – Patterns of Expression and Potential Functions of Proto-oncogenes during Mammalian Spermatogenesis

  1993cites this paper
• Comparison of baculovirus-expressed c-Abl and BCR/ABL protein tyrosine kinases.

  1993cites this paper
• Malignant transformation by abl and BCR/ABL.

  1993cites this paper
• En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase.

  1993cites this paper
• c-abl has a sequence-specific enhancer binding activity.

  1992cites this paper
• Expression of Proto-Oncogenes and Protein Kinases in the Testis

  1992cites this paper
• Humanbcr-abl gene has a lethal effect on embryogenesis

  1991cites this paper
• Implicating the bcr/abl gene in the pathogenesis of Philadelphia chromosome-positive human leukemia.

  1991cites this paper
• Carboxyl-terminal determinants of Abelson protein important for lymphoma induction

  1991cites this paper
• Inhibition of P210BCR/ABL Expression in K562 Cells by Electroporation with an Antisense Oligonucleotide.

  1990cites this paper
• The complete coding sequence of arg defines the Abelson subfamily of cytoplasmic tyrosine kinases.

  1990cites this paper
• A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization.

  1990cites this paper
• Nucleotide sequence analysis of human abl and bcr-abl cDNAs.

  1989cites this paper
• Structures and activities of activated abl oncogenes.

  1989cites this paper
• P150c-abl is detected in mouse male germ cells by an in vitro kinase assay and is associated with stage-specific phosphoproteins in haploid cells.

  1989cites this paper
• abl genes.

  1989cites this paper
• The viral and cellular forms of the Abelson (abl) oncogene.

  1988cites this paper
• Selective transformation of primitive lymphoid cells by the BCR/ABL oncogene expressed in long-term lymphoid or myeloid cultures

  1988cites this paper
• Role of the ABL oncogene tyrosine kinase activity in human leukaemia.

  1987cites this paper